Twisted Masses and Enhanced Symmetries: the A&D Series

We study new symmetries between A and D type quiver gauge theories with different numbers of colors. We realize these gauge theories with twisted masses via a brane construction that reproduces all the parameters of the Gauge/Bethe correspondence.Comment: 14 pages, 5 figure

Seiberg-Witten prepotential for E-string theory and global symmetries

We obtain Nekrasov-type expressions for the Seiberg-Witten prepotential for the six-dimensional (1,0) supersymmetric E-string theory compactified on T^2 with nontrivial Wilson lines. We consider compactification with four general Wilson line parameters, which partially break the E_8 global symmetry. In particular, we investigate in detail the cases where the Lie algebra of the unbroken global symmetry is E_n + A_{8-n} with n=8,7,6,5 or D_8. All our Nekrasov-type expressions can be viewed as special cases of the elliptic analogue of the Nekrasov partition function for the SU(N) gauge theory with N_f=2N flavors. We also present a new expression for the Seiberg-Witten curve for the E-string theory with four Wilson line parameters, clarifying the connection between the E-string theory and the SU(2) Seiberg-Witten theory with N_f=4 flavors.Comment: 22 pages. v2: comments and a reference added, version to appear in JHE

Nodular Fasciitis with Cortical Erosion of the Hand

Nodular fasciitis is a benign, reactive myofibroblastic tumor that is often mistaken for a sarcoma because of its histological appearance and rapid growth. Involvement of a finger is extremely rare. We report a case of nodular fasciitis of the thumb, accompanied by bone erosion. Magnetic resonance findings suggested the possibility of a malignancy, which could have led to misdiagnosis as a malignant soft tissue sarcoma. Instead, the lesion was treated by excisional biopsy, which confirmed nodular fasciitis. There has been no evidence of local recurrence at recent follow-up, 1 year after surgery. This case illustrates that, to avoid unnecessarily aggressive surgery, nodular fasciitis must be included in the differential diagnosis for any finger lesion that resembles a sarcoma, even if bone erosion is present

Suture Materials, 1980s: Properties, Uses, and Abuses

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66057/1/j.1365-4362.1982.tb03154.x.pd

Refined Cigar and Omega-deformed Conifold

Antoniadis et al proposed a relation between the Omega-deformation and refined correlation functions of the topological string theory. We investigate the proposal for the deformed conifold geometry from a non-compact Gepner model approach. The topological string theory on the deformed conifold has a dual description in terms of the c=1 non-critical string theory at the self-dual radius, and the Omega-deformation yields the radius deformation. We show that the refined correlation functions computed from the twisted SL(2,R)/U(1) Kazama-Suzuki coset model at level k=1 have direct c=1 non-critical string theory interpretations. After subtracting the leading singularity to procure the 1PI effective action, we obtain the agreement with the proposal.Comment: 15 pages, v2: reference added, v3: published versio

Non-perturbative effects and the refined topological string

The partition function of ABJM theory on the three-sphere has non-perturbative corrections due to membrane instantons in the M-theory dual. We show that the full series of membrane instanton corrections is completely determined by the refined topological string on the Calabi-Yau manifold known as local P1xP1, in the Nekrasov-Shatashvili limit. Our result can be interpreted as a first-principles derivation of the full series of non-perturbative effects for the closed topological string on this Calabi-Yau background. Based on this, we make a proposal for the non-perturbative free energy of topological strings on general, local Calabi-Yau manifolds.Comment: 38 pages, 5 figure

Direct Integration and Non-Perturbative Effects in Matrix Models

We show how direct integration can be used to solve the closed amplitudes of multi-cut matrix models with polynomial potentials. In the case of the cubic matrix model, we give explicit expressions for the ring of non-holomorphic modular objects that are needed to express all closed matrix model amplitudes. This allows us to integrate the holomorphic anomaly equation up to holomorphic modular terms that we fix by the gap condition up to genus four. There is an one-dimensional submanifold of the moduli space in which the spectral curve becomes the Seiberg--Witten curve and the ring reduces to the non-holomorphic modular ring of the group $\Gamma(2)$. On that submanifold, the gap conditions completely fix the holomorphic ambiguity and the model can be solved explicitly to very high genus. We use these results to make precision tests of the connection between the large order behavior of the 1/N expansion and non-perturbative effects due to instantons. Finally, we argue that a full understanding of the large genus asymptotics in the multi-cut case requires a new class of non-perturbative sectors in the matrix model.Comment: 51 pages, 8 figure

Multi-parallel qPCR provides increased sensitivity and diagnostic breadth for gastrointestinal parasites of humans: field-based inferences on the impact of mass deworming

BACKGROUND: Although chronic morbidity in humans from soil transmitted helminth (STH) infections can be reduced by anthelmintic treatment, inconsistent diagnostic tools make it difficult to reliably measure the impact of deworming programs and often miss light helminth infections. METHODS: Cryopreserved stool samples from 796 people (aged 2-81 years) in four villages in Bungoma County, western Kenya, were assessed using multi-parallel qPCR for 8 parasites and compared to point-of-contact assessments of the same stools by the 2-stool 2-slide Kato-Katz (KK) method. All subjects were treated with albendazole and all Ascaris lumbricoides expelled post-treatment were collected. Three months later, samples from 633 of these people were re-assessed by both qPCR and KK, re-treated with albendazole and the expelled worms collected. RESULTS: Baseline prevalence by qPCR (n = 796) was 17 % for A. lumbricoides, 18 % for Necator americanus, 41 % for Giardia lamblia and 15% for Entamoeba histolytica. The prevalence was <1% for Trichuris trichiura, Ancylostoma duodenale, Strongyloides stercoralis and Cryptosporidium parvum. The sensitivity of qPCR was 98% for A. lumbricoides and N. americanus, whereas KK sensitivity was 70% and 32%, respectively. Furthermore, qPCR detected infections with T. trichiura and S. stercoralis that were missed by KK, and infections with G. lamblia and E. histolytica that cannot be detected by KK. Infection intensities measured by qPCR and by KK were correlated for A. lumbricoides (r = 0.83, p < 0.0001) and N. americanus (r = 0.55, p < 0.0001). The number of A. lumbricoides worms expelled was correlated (p < 0.0001) with both the KK (r = 0.63) and qPCR intensity measurements (r = 0.60). CONCLUSIONS: KK may be an inadequate tool for stool-based surveillance in areas where hookworm or Strongyloides are common or where intensity of helminth infection is low after repeated rounds of chemotherapy. Because deworming programs need to distinguish between populations where parasitic infection is controlled and those where further treatment is required, multi-parallel qPCR (or similar high throughput molecular diagnostics) may provide new and important diagnostic information