Seagrasses and seagrass habitats in Pacific small island developing states: potential loss of benefits via human disturbance and climate change

Seagrasses provide a wide range of services including food provision, water purification and coastal protection. Pacific small island developing states (PSIDS) have limited natural resources, challenging economies and a need for marine science research. Seagrasses occur in eleven PSIDS and nations are likely to benefit in different ways depending on habitat health, habitat cover and location, and species presence. Globally seagrass habitats are declining as a result of anthropogenic impacts including climate change and in PSIDS pressure on already stressed coastal ecosystems, will likely threaten seagrass survival particularly close to expanding urban settlements. Improved coastal and urban planning at local, national and regional scales is needed to reduce human impacts on vulnerable coastal areas. Research is required to generate knowledge-based solutions to support effective coastal management and protection of the existing seagrass habitats, including strenghened documentation the socio-economic and environmental services they provide. For PSIDS, protection of seagrass service benefits requires six priority actions: seagrass habitat mapping, regulation of coastal and upstream development, identification of specific threats at vulnerable locations, a critique of cost-effective restoration options, research devoted to seagrass studies and more explicit policy development

The geography of wage inequality in British cities

There is widespread concern about the scale and implications of urban inequality in Great Britain, but little evidence on which cities are the most unequal and why. This paper investigates patterns of wage inequality in 60 British cities. It has two principal goals: (1) to describe which cities are most unequal and (2) to assess the important determinants of inequality. The results show a distinct geography of wage inequality, the most unequal cities tend to be affluent and located in parts of the Greater South East of England. A central determinant of these patterns is the geography of highly skilled workers. Because of this, the geography of urban wage inequality reflects the geography of affluence more generally

Enabling planetary science across light-years. Ariel Definition Study Report

Ariel, the Atmospheric Remote-sensing Infrared Exoplanet Large-survey, was adopted as the fourth medium-class mission in ESA's Cosmic Vision programme to be launched in 2029. During its 4-year mission, Ariel will study what exoplanets are made of, how they formed and how they evolve, by surveying a diverse sample of about 1000 extrasolar planets, simultaneously in visible and infrared wavelengths. It is the first mission dedicated to measuring the chemical composition and thermal structures of hundreds of transiting exoplanets, enabling planetary science far beyond the boundaries of the Solar System. The payload consists of an off-axis Cassegrain telescope (primary mirror 1100 mm x 730 mm ellipse) and two separate instruments (FGS and AIRS) covering simultaneously 0.5-7.8 micron spectral range. The satellite is best placed into an L2 orbit to maximise the thermal stability and the field of regard. The payload module is passively cooled via a series of V-Groove radiators; the detectors for the AIRS are the only items that require active cooling via an active Ne JT cooler. The Ariel payload is developed by a consortium of more than 50 institutes from 16 ESA countries, which include the UK, France, Italy, Belgium, Poland, Spain, Austria, Denmark, Ireland, Portugal, Czech Republic, Hungary, the Netherlands, Sweden, Norway, Estonia, and a NASA contribution

Exercise, appetite and weight management: Understanding the compensatory responses in eating behaviour and how they contribute to variability in exercise-induced weight loss

Does exercise promote weight loss? One of the key problems with studies assessing the efficacy of exercise as a method of weight management and obesityis that mean data are presented and the individual variability in response is overlooked. Recent data have highlighted the need to demonstrate and characterise the individual variability in response to exercise. Do people who exercise compensate for the increase in energy expenditure via compensatory increases in hunger and food intake? The authors address the physiological, psychological and behavioural factors potentially involved in the relationship between exercise and appetite, and identify the research questions that remain unanswered. A negative consequence of the phenomena of individual variability and compensatory responses has been the focus on those who lose little weight in response to exercise; this has been used unreasonably as evidence to suggest that exercise is a futile method of controlling weight and managing obesity. Most of the evidence suggests that exercise is useful for improving body composition and health. For example, when exercise-induced mean weight loss is <1.0 kg, significant improvements in aerobic capacity (+6.3 ml/kg/min), systolic (−6.00 mm Hg) and diastolic (−3.9 mm Hg) blood pressure, waist circumference (−3.7 cm) and positive mood still occur. However, people will vary in their responses to exercise; understanding and characterising this variability will help tailor weight loss strategies to suit individuals

EdTech for Ugandan girls: Affordances of different technologies for girls' secondary education during the Covid-19 pandemic.

MOTIVATION: This article discusses the use of educational technology (EdTech) in girls' education at PEAS (Promoting Education in African Schools) schools in rural Uganda during the Covid-19-related school closures. PURPOSE: This article addresses a research gap surrounding the potential use of EdTech to support girls' education, focusing on the barriers to girls' EdTech use and how technology might be used to enhance girls' education in disadvantaged rural areas-specifically their academic learning and their social and emotional learning. METHODS AND APPROACH: A sequential, explanatory mixed-methods case-study approach was used. Quantitative exploration of a dataset of 483 Ugandan students, from 28 PEAS schools, was first conducted, followed by interviews with PEAS staff to elucidate the reasons and context behind the findings. FINDINGS: Findings show that female students are less likely than male students to have access to their caregivers' phones for learning. The form of EdTech that appeared to be most beneficial for girls' academic learning was radio; girls also had significantly more interest in tuning into radio broadcasts than boys did. Also, poorer boys were more likely to be influenced by SMS messages than wealthier boys. Apart from gender-based differences, students with more highly educated parents found SMS messages more helpful, and phone calls from teachers appeared to help boost younger students' self-confidence. POLICY IMPLICATIONS: The findings suggest that policy-makers need to: carefully consider provision of education through multiple modes of EdTech in order to ensure that it reaches all students; ensure that caregivers are involved in the strategies developed for girls' education; make EdTech interventions interactive; and consider language in EdTech interventions. Given the gender differences which emerged, the findings are of relevance both to supporting the continuation of educational provision during periods of school closure, and also in terms of finding additional ways to support girls' education alongside formal schooling

Global CO2 Initiative Complete Mineralization Study 2018

This document contains worked examples of how to apply the accompanying “Guideline for Techno-Economic Assessment of CO2 Utilization” and “Guideline for Life Cycle Assessment of CO2 Utilization”. The Guidelines can be downloaded via http://hdl.handle.net/2027.42/145436. These worked examples are not intended to be a definitive TEA or LCA report on the process described, but are provided as supporting material to show how the TEA and LCA methodologies described in the guidelines can be specifically applied to tackle the issues surrounding CO2 utilization. This document contains worked examples of how to apply the accompanying “Guideline for Techno- Economic Assessment of CO2 Utilization” and “Guideline for Life Cycle Assessment of CO2 Utilization”, hereafter referred to as "the TEA and LCA guidelines". These worked examples are not intended to be a definitive TEA or LCA report on the process described, but are provided as supporting material to show how the TEA and LCA methodologies described in the guidelines can be specifically applied to tackle the issues surrounding CO2 utilization. This example was constructed using data collected from a demonstration plant operated by Carbon8 Systems in Ontario, Canada, together with data obtained from the literature and from the ecoinvent database v3.4. As with the methanol worked example, the aim is not to prove whether the selected process is economically or environmentally viable or to make process alterations to make it so, but to clearly demonstrate how the proposed guidelines can be used to conduct a transparent TEA and LCA which can then be followed by others. The TEA example is provided in Part B, followed by the LCA example in Part C. In Part D, the reader will find a short example of how a TEA and LCA can be integrated. This integration is not an exhaustive example. As many aspects can be analyzed to produce combined indicators and many approaches to multi-criteria decision making applied. However, it is included here to provide a starting point and initial example of how integration can be carried out.CO2 Sciences, Inc.EIT Climate-KIC3MCO2 Value EuropeEmissions Reduction AlbertaThe Grantham FoundationRichard King Mellon FoundationThe Cynthia&George Mitchell FoundationNICE AmericaPraxairNRG Cosia Carbon XPrizePeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147467/3/Global CO2 Initiative Complete Mineralization Study 2018.pdf2

The interaction between exercise, appetite and food intake : implications for weight control

Exercise could indirectly affect body weight by exerting changes on various components of appetite control, including nutrient and taste preferences, meal size and frequency, and the drive to eat. This review summarizes the evidence on how exercise affects appetite and eating behavior and in particular answers the question, “Does exercise induce an increase in food intake to compensate for the increase in energy expenditure?” Evidence will be presented to demonstrate that there is no automatic increase in food intake in response to acute exercise and that the response to repeated exercise is variable. The review will also identify areas of further study required to explain the variability. One limitation with studies that assess the efficacy of exercise as a method of weight control is that only mean data are presented—the individual variability tends to be overlooked. Recent evidence highlights the importance of characterizing the individual variability by demonstrating exercise-induced changes in appetite. Individuals who experience lower than theoretically predicted reductions in body weight can be characterized by hedonic (eg, pleasure) and homeostatic (eg, hunger) features

Prospective Minimal Residual Disease Monitoring to Predict Relapse of Acute Promyelocytic Leukemia and to Direct Pre-Emptive Arsenic Trioxide Therapy

PurposeMolecular diagnostics and early assessment of treatment response that use methodologies capable of detecting submicroscopic disease can distinguish subgroups of patients with leukemia at differing relapse risk. Such information is being incorporated into risk-stratified protocols; however, there are few data concerning prospective use of sequential minimal residual disease (MRD) monitoring to identify more precisely those patients destined to experience relapse, which would allow more tailored therapies.MethodsReal-time quantitative polymerase chain reaction (RQ-PCR) assays to detect leukemia-specific transcripts (ie, PML-RARA, RARA-PML) were used to prospectively analyze 6,727 serial blood and marrow samples from 406 patients with newly diagnosed acute promyelocytic leukemia (APL) who were receiving all-trans-retinoic acid and anthracycline-based chemotherapy.ResultsMRD monitoring according to the recommended schedule successfully identified the majority of patients subject to relapse and provided the most powerful predictor of relapse-free survival (RFS) in multivariable analysis (hazard ratio, 17.87; 95% CI, 6.88 to 46.41; P < .0001); MRD monitoring was far superior to presenting WBC (hazard ratio, 1.02; 95% CI, 1.00 to 1.03; P = .02), which is currently widely used to guide therapy. In patients who were predicted to experience relapse on the basis of MRD monitoring, early treatment intervention with arsenic trioxide prevented progression to overt relapse in the majority, and the RFS rate at 1 year from molecular relapse was 73%. By using this strategy, 3-year cumulative incidence of clinical relapse was only 5% in the Medical Research Council AML15 trial.ConclusionRigorous sequential RQ-PCR monitoring provides the strongest predictor of RFS in APL and, when coupled with pre-emptive therapy, provides a valid strategy to reduce rates of clinical relapse. This provides a model for development of a more individualized approach to management of other molecularly defined subtypes of acute leukemia. J Clin Oncol 27: 3650-3658. (C) 2009 by American Society of Clinical Oncolog