The Theology of Self-Surrender in the Writings of E. Stanley Jones

This thesis seeks to grapple with one of the most crucial issues confronting Christian theology today, namely, what to make of the insights and discoveries of the newer disciplines of psychology, psychoanalysis, psychiatry, psychotherapy, etc. For a while psychology proceeded as though theology did not exist or as though it were a remnant of the superstitions of a previous age. However, in recent years psychological practitioners outside the church have shown somewhat greater interest in the religious life of their patients and in the role of religious life of their patients and in the role of religious life and practice in mental health and illness. Both Christianity and psychology describe in considerable detail the distortions of human existence under the pressures of anxiety and estrangement. Both seek the transformation of the personality rather than the mere suppression of symptoms. These two disciplines, therefore, cannot remain aloof from each other. While retaining their respective and distinctive roles, they must become allies. The basic purpose of this investigation has been to make a critical appraisal of E. Stanley Jones\u27 concept of conversion from a theological and psychological frame of reference. Both the field of psychology and theology are extremely sensitive. Yet, in the popular writings of one of the most outstanding writers of our generation, that of E. Stanley Jones\u27, these two disciplines converge

The Founder’s Lecture 2009: advances in imaging of osteoporosis and osteoarthritis

The objective of this review article is to provide an update on new developments in imaging of osteoporosis and osteoarthritis over the past three decades. A literature review is presented that summarizes the highlights in the development of bone mineral density measurements, bone structure imaging, and vertebral fracture assessment in osteoporosis as well as MR-based semiquantitative assessment of osteoarthritis and quantitative cartilage matrix imaging. This review focuses on techniques that have impacted patient management and therapeutic decision making or that potentially will affect patient care in the near future. Results of pertinent studies are presented and used for illustration. In summary, novel developments have significantly impacted imaging of osteoporosis and osteoarthritis over the past three decades

A systematic review showing the lack of diagnostic criteria and tools developed for lower-limb cellulitis

BACKGROUND: Cellulitis can be a difficult diagnosis to make. Furthermore, 31% of patients admitted from the emergency department with suspected lower-limb cellulitis have been misdiagnosed, with incorrect treatment potentially resulting in avoidable hospital admission and the prescription of unnecessary antibiotics. OBJECTIVES: We sought to identify diagnostic criteria or tools that have been developed for lower-limb cellulitis. METHODS: We conducted a systematic review using Ovid MEDLINE and Embase databases in May 2018, with the aim of describing diagnostic criteria and tools developed for lower-limb cellulitis, and we assessed the quality of the studies identified using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. We included all types of study that described diagnostic criteria or tools. RESULTS: Eight observational studies were included. Five studies examined biochemical markers, two studies assessed imaging and one study developed a diagnostic decision model. All eight studies were considered to have a high risk for bias in at least one domain. The quantity and quality of available data was low and results could not be pooled owing to the heterogeneity of the findings. CONCLUSIONS: There is a lack of high-quality publications describing criteria or tools for diagnosing lower-limb cellulitis. Future studies using prospective designs, validated in both primary and secondary care settings, are needed. What's already known about this topic? Diagnosing lower-limb cellulitis on first presentation is challenging. Approximately one in three patients admitted from the emergency department with suspected lower-limb cellulitis do not have cellulitis and are given another diagnosis on discharge. Consequently, this results in potentially avoidable hospital admissions and the prescription of unnecessary antibiotics. There are no diagnostic criteria available for lower-limb cellulitis in the U.K. What does this study add? This systematic review has identified a key research gap in the diagnosis of lower-limb cellulitis. There is a current lack of robustly developed and validated diagnostic criteria or tools for use in clinical practice

The Comparative Effects of Carbohydrates and Lipids on Mitochondrial Function

Non-alcoholic fatty liver disease (NAFLD) and Type 2 Diabetes affect approximately 24% and 8% of the global population respectively. The Western diet, high in both carbohydrates and lipids, is believed to have a role in the development of chronic metabolic disease. Dysfunctional hepatic mitochondrial metabolism is also known to be a central feature of disordered metabolism. The objective of this study was to compare the roles of dietary carbohydrates vs. lipids in inducing dysfunctional hepatic mitochondrial metabolism. Mice, C57BL/6NJ were kept on one of three diets: low-fat control (LF; 10% kcal fat), high-fat (HF; 60% kcal fat), and high-carbohydrate (HC; 25% kcal fat and 34.9% kcal fructose) for 10 weeks. Half of the mice were randomly selected to undergo a 16 hour fast prior to sacrifice, while the other half were not fasted. Within the fasted subset, the HC diet induced significantly elevated basal mitochondrial respiration (pmol Oxygen consumed/min) when compared with HF (HF, 70.1±5.8; HC,108.6±17.4; p<.05). Among fasted mice, the HC diet also appeared to induce significantly higher maximal respiration and ATP production when compared with HF. Expression of hepatic mitochondrial complex proteins were also higher in fasted HC mice than fasted HF mice. Overall, these results suggest that the high-carbohydrate diet enhanced mitochondrial activity when compared with the high-fat diet