369 research outputs found

    Cyclical Unemployment: Sectoral Shifts or Aggregate Disturbances?

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    Recent work by David Lilien has argued that the existence of a strong positive correlation between the dispersion of employment growth rates across sectors (G) and the unemployment rate implies that shifts in demand from some sectors to others are responsible for a substantial fraction of cyclical variation in unemployment. This paper demonstrates that, under certain empirically satisfied conditions, aggregate demand movements alone can produce a positive correlation between G and the unemployment rate. Two tests are developed which permit one to distinquish between a pure sectoral shift interpretation and a pure aggregate demand interpretation of this positive correlation. The finding that G and the volume of help wanted advertising are negatively related and the finding that G is directly associated with the change in unemployment rather than with the level of unemployment both support an aggregate demand interpretation. A proxy for sectoral shifts that is purged of the influence of aggregate demand is then developed. Models which allow sectoral shifts in the composition of demand and fluctuations in the aggregate level of demand to affect the unemployment rate independently are estimated using this proxy. The results support the view that pure sectoral shifts have not been an important source of cyclical fluctuations in unemployment.

    Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer.

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    Breast cancer is a common cancer that occurs due to different epigenetic alterations and genetic mutations. Various epidemiological studies have demonstrated an inverse correlation between breast cancer incidence and flavonoid intake. The anti-cancer action of flavonoids, a class of polyphenolic compounds that are present in plants, as secondary metabolites has been a major topic of research for many years. Our review analysis demonstrates that flavonoids exhibit anti-cancer activity against breast cancer occurring in different ethnic populations. Breast cancer subtype and menopausal status are the key factors in inducing the flavonoid\u27s anti-cancer action in breast cancer. The dose is another key factor, with research showing that approximately 10 mg/day of isoflavones is required to inhibit breast cancer occurrence. In addition, flavonoids also influence the epigenetic machinery in breast cancer, with research demonstrating that epigallocatechin, genistein, and resveratrol all inhibited DNA methyltransferase and altered chromatin modification in breast cancer. These flavonoids can induce the expression of different tumor suppressor genes that may contribute to decreasing breast cancer progression and metastasis. Additional studies are required to confirm the contribution of epigenetic modifications by flavonoids to breast cancer prevention

    Conjuring the Close from Afar A Border-Crossing Tale of Vieques’ Activism and Obama-Empire

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    After more than 60 years of military occupation, 30 of these under violent military practices, a social movement forced the U.S. Navy from the island of Vieques. This victory would not have been possible without the highly effective organization of civil disobedience carried out on the island. But the sum total of the actions that eventually forced out the U.S. Navy, neither happened exclusively within the boundaries of Vieques, nor was carried out by Viequense residents alone. In this article we want to suggest that this amazing victory—a testament of people’s will in the face of globalization—is also a border- crossing tale. Drawing from interviews with key activists currently based in Puerto Rico and New York, this article will explore the myriad routes of connections enacted, maintained and negotiated within and beyond territorial and ethnic boundaries. It will particularly look at how various activists conjured networks of solidarity, kinship, political affiliation, and friendship, among others, in their quest to liberate the island from the U.S. military occupation. Under the backdrop of Obama’s post-racial discourse, this paper illustrates how the Vieques movement circumvented the politics of Empire through creative maneuvers and negotiations

    Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic

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    Preparing for a Northwest Passage: A Workshop on the Role of New England in Navigating the New Arctic (March 25 - 27, 2018 -- The University of New Hampshire) paired two of NSF\u27s 10 Big Ideas: Navigating the New Arctic and Growing Convergence Research at NSF. During this event, participants assessed economic, environmental, and social impacts of Arctic change on New England and established convergence research initiatives to prepare for, adapt to, and respond to these effects. Shipping routes through an ice-free Northwest Passage in combination with modifications to ocean circulation and regional climate patterns linked to Arctic ice melt will affect trade, fisheries, tourism, coastal ecology, air and water quality, animal migration, and demographics not only in the Arctic but also in lower latitude coastal regions such as New England. With profound changes on the horizon, this is a critical opportunity for New England to prepare for uncertain yet inevitable economic and environmental impacts of Arctic change

    Attitudes towards microbicide use for bacterial vaginosis in pregnancy

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    Background Bacterial vaginosis (BV) is the most common reproductive tract infection (RTI) and is a significant risk factor for preterm birth. Microbicides could be an option for the prevention and treatment of BV in pregnancy, and understanding use of the product will be crucial. The present study explored attitudes of women in the third trimester of pregnancy regarding topical microbicide use for the prevention and treatment of BV. METHODS: Twenty-six women in their third trimester were interviewed regarding their knowledge and beliefs about RTIs during pregnancy and attitudes concerning the use of topical microbicides for prevention and treatment of BV. RESULTS: Participants had a mean age of 24.9 years, were largely under-represented minorities and the majority had had past pregnancies. Participants had knowledge and experience with RTIs but not BV. They were open to the use of microbicides for prevention or treatment of BV, but believed that women requiring treatment would be more motivated. Rationales for acceptability were most commonly related to the baby's health. Practical issues that may interfere with use were often, but not always, related to pregnancy. There was a range of attitudes about partner involvement in decision-making and the practicalities of product use. CONCLUSION: Pregnant women are knowledgeable about RTIs but not necessarily BV. The women in this study found microbicide use acceptable, particularly for treatment. To improve acceptability and use, education would be needed about BV and possible complications, how to overcome practical problems and the value of involving partners in the decision

    The Southampton Initiative for Health:A Complex Intervention to Improve the Diets and Increase the Physical Activity Levels of Women from Disadvantaged Communities

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    The Southampton Initiative for Health is a training intervention with Sure Start Children’s Centre staff designed to improve the diets and physical activity levels of women of childbearing age. Training aims to help staff to support women in making changes to their lifestyles by improving three skills: reflection on current practice; asking ‘open discovery’ questions; and goal-setting. The impact of the training on staff practice is being assessed. A before and after non-randomized controlled trial is being used to evaluate the effectiveness and cost-effectiveness of the intervention in improving women’s diets and increasing their physical activity levels

    Extending the Dynamic Model of Situated Cognition to Submarine Command and Control

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    ABSTRACT A necessary step in the process of enhancing Sea Warrior performance is the ability to analyze performance via a comprehensive HumanSystem approach. Such an approach to Human -System performance has been espoused by researchers (Miller & Shattuck, 2004) in the study of military command and control. Citing the gap between the focus of analysis of human factors practitioners and systems analysts, Miller and Shattuck describe a dynamic model of situated cognition (DMSC) in which cognitive activities are based on the data which flow from the environment through the machine portions of a complex system. This approach overcomes the limitations of measures used to assess cognitive performance, such as some situational awareness (SA) metrics, that implicitly depict the activity as a state rather than a dynamic process. Moreover, by utilizing the DMSC, military accidents can be analyzed retrospectively to pinpoint root causes and identify ways to improve future performance. As an example, this paper applies the DMSC to two Naval submarine mishaps
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