Surface rupture of multiple crustal faults in the 2016 Mw 7.8 Kaikōura, New Zealand, earthquake

Multiple (>20 >20 ) crustal faults ruptured to the ground surface and seafloor in the 14 November 2016 M w Mw 7.8 Kaikōura earthquake, and many have been documented in detail, providing an opportunity to understand the factors controlling multifault ruptures, including the role of the subduction interface. We present a summary of the surface ruptures, as well as previous knowledge including paleoseismic data, and use these data and a 3D geological model to calculate cumulative geological moment magnitudes (M G w MwG ) and seismic moments for comparison with those from geophysical datasets. The earthquake ruptured faults with a wide range of orientations, sense of movement, slip rates, and recurrence intervals, and crossed a tectonic domain boundary, the Hope fault. The maximum net surface displacement was ∼12  m ∼12  m on the Kekerengu and the Papatea faults, and average displacements for the major faults were 0.7–1.5 m south of the Hope fault, and 5.5–6.4 m to the north. M G w MwG using two different methods are M G w MwG 7.7 +0.3 −0.2 7.7−0.2+0.3 and the seismic moment is 33%–67% of geophysical datasets. However, these are minimum values and a best estimate M G w MwG incorporating probable larger slip at depth, a 20 km seismogenic depth, and likely listric geometry is M G w MwG 7.8±0.2 7.8±0.2 , suggests ≤32% ≤32% of the moment may be attributed to slip on the subduction interface and/or a midcrustal detachment. Likely factors contributing to multifault rupture in the Kaikōura earthquake include (1) the presence of the subduction interface, (2) physical linkages between faults, (3) rupture of geologically immature faults in the south, and (4) inherited geological structure. The estimated recurrence interval for the Kaikōura earthquake is ≥5,000–10,000  yrs ≥5,000–10,000  yrs , and so it is a relatively rare event. Nevertheless, these findings support the need for continued advances in seismic hazard modeling to ensure that they incorporate multifault ruptures that cross tectonic domain boundaries

A systematic review of the diagnostic accuracy of the H2S test versus indicator bacteria tests for faecal contamination of water

The H2S test, a simple, low-cost field test, is used in many remote and developing country settings to test for the faecal contamination of drinking-water. However, its diagnostic accuracy remains uncertain. To provide more guidance on its use, we assessed the diagnostic accuracy of the H2S test versus indicator bacterial tests for E. coli or thermotolerant coliforms (TTC). We screened 661 abstracts and identified 51 relevant studies based on 13,853 water samples. The overall test sensitivity and specificity (95% CI) was 0.87 (0.80-0.92) and 0.82 (0.72-0.90) relative to TTC and 0.88 (0.77-0.94) and 0.75 (0.55–0.88) relative to E. coli tests. The test’s diagnostic accuracy varied significantly and substantially between studies. Little of this variation was explained by testing procedures, study quality or the nature of the samples processed. We recommended that users should benchmark its accuracy before using in a new setting

Collaborative, individualised lifestyle interventions are acceptable to people with first episode psychosis; a qualitative study

Abstract Background The adverse impact of unhealthy lifestyle choices and the prescription of antipsychotic medications contribute to weight gain, poor cardiovascular health and reduced life expectancy for people with psychosis. The present study aimed to explore the acceptability and perceived outcomes of a lifestyle intervention designed to prevent or reduce weight gain in people with first-episode psychosis. Methods This was a qualitative study using a data-driven approach. People recovering from first-episode psychosis recruited from UK early intervention services and taking part in the active arm of a randomised controlled trial of a lifestyle intervention (the InterACT trial), were interviewed using a semi-structured interview schedule. Interviews were transcribed verbatim and analysed using Framework Analysis. Results Participants valued the collaborative and individualised approach taken by the intervention deliverers, and formed high quality relationships with them. Aspects of the intervention that were positively appraised included goal setting, social opportunities, and progress monitoring. Benefits of the intervention, including increased levels of exercise; improved diet and physical health; increased psychological wellbeing (e.g. confidence, self-esteem); and improved social relationships, were identified by participants, independent of actual weight loss. Conclusions Future interventions should ensure that workers have the skills to form high quality relationships with users, and to individualise the intervention according to users’ needs and preferences. Future trials that test healthy living interventions should consider supplementing physical outcome measures with wider psychosocial outcome assessments, in particular social relationship quality, psychological wellbeing, self-esteem and self-efficacy. Trial registration Current Controlled Trials: ISRCTN22581937. Date of registration: 27 October 2010 (retrospectively registered)

Collaborative, individualised lifestyle interventions are acceptable to people with first episode psychosis; a qualitative study

Abstract Background The adverse impact of unhealthy lifestyle choices and the prescription of antipsychotic medications contribute to weight gain, poor cardiovascular health and reduced life expectancy for people with psychosis. The present study aimed to explore the acceptability and perceived outcomes of a lifestyle intervention designed to prevent or reduce weight gain in people with first-episode psychosis. Methods This was a qualitative study using a data-driven approach. People recovering from first-episode psychosis recruited from UK early intervention services and taking part in the active arm of a randomised controlled trial of a lifestyle intervention (the InterACT trial), were interviewed using a semi-structured interview schedule. Interviews were transcribed verbatim and analysed using Framework Analysis. Results Participants valued the collaborative and individualised approach taken by the intervention deliverers, and formed high quality relationships with them. Aspects of the intervention that were positively appraised included goal setting, social opportunities, and progress monitoring. Benefits of the intervention, including increased levels of exercise; improved diet and physical health; increased psychological wellbeing (e.g. confidence, self-esteem); and improved social relationships, were identified by participants, independent of actual weight loss. Conclusions Future interventions should ensure that workers have the skills to form high quality relationships with users, and to individualise the intervention according to users’ needs and preferences. Future trials that test healthy living interventions should consider supplementing physical outcome measures with wider psychosocial outcome assessments, in particular social relationship quality, psychological wellbeing, self-esteem and self-efficacy. Trial registration Current Controlled Trials: ISRCTN22581937. Date of registration: 27 October 2010 (retrospectively registered)

Association Between Prolactin and Incidence of Cardiovascular Risk Factors in the Framingham Heart Study

Background: Prolactin is an anterior pituitary hormone that may modulate the adverse effects of obesity. Prolactin has been associated with cardiovascular disease mortality, but less is known about whether prolactin predicts incidence of cardiovascular disease risk factors. Methods and Results: Our sample (n=3232, mean age 40.4 years, 52.1% women) was drawn from Framingham Heart Study participants who attended 2 examinations an average of 6.1 years apart. After excluding those with elevated prolactin (>30 mg/dL for women, >20 mg/dL for men), multivariable‐adjusted regressions modeled the associations between baseline prolactin and changes in cardiovascular disease risk factors. Models were adjusted for age, sex, baseline value of the risk factor, smoking status, hormone replacement therapy, and menopausal status and additionally for body mass index. Mean prolactin levels were 11.9 mg/dL (SD 5.2) in women and 8.0 mg/dL (SD 2.9) in men. No associations were observed for change in weight, body composition, total cholesterol, triglycerides, or fasting glucose. In women, for example, for each 5‐mg/dL increment in prolactin, odds of incident hypercholesterolemia were 1.06, which was not significant (95% CI 0.91–1.23, P=0.46). Some exceptions were of note. In women, for each 5‐mg/dL increment in prolactin, we observed increased odds of low high‐density lipoprotein cholesterol at follow‐up (odds ratio 1.50, 95% CI 1.18–1.91, P=0.001) that persisted after adjustment for body mass index (P=0.001). In men, a 5‐mg/dL increment in prolactin was associated with increased odds of incident hypertension (odds ratio 1.61, 95% CI 1.18–2.20 P=0.002) and incident diabetes (odds ratio 1.70, 95% CI 1.04–2.78, P=0.03). Conclusions: Prolactin is not associated with a comprehensive panel of incident cardiovascular disease risk factors. Measurement of circulating prolactin levels in the community likely does not provide substantial insight into cardiometabolic risk

Evaluating the health-related quality of life effects of cochlear implants: a prospective study of an adult cochlear implant program

This paper prospectively documents the health-related quality of life (HRQoL) and social participation benefits of adult patients receiving cochlear implants in Australia and New Zealand. Thirty-four consecutively implanted patients completed the Assessment of Quality of Life (AQoL) and Hearing Participation Scale (HPS) instruments before implantation, and at 3- and 6-month follow-ups. Implantation resulted in significant improvements in AQoL and HPS scores. The effect size was 1.09 for both measures. Those in the top socio-economic tertile obtained the greatest gains. The HRQoL and social participation benefits were slightly larger than those reported elsewhere. This may be because participants used more recent technology (Nucleus 24 rather than Nucleus 22) and received auditory and self-efficacy training as part of their rehabilitation. The results suggest that cochlear implants have a large beneficial effect. They show that social and HRQoL outcomes can be parsimoiously measured using the HPS and AQoL instruments.10 page(s

Workshop Report: Developing Pollution Source Tracking for Recreational and Shellfish Waters

The Environment Agency of England and Wales obtained European Community Initiative INTERREG IIIB funding for a project called ICReW—Improving Coastal and Recreational Waters. The project consists of seven pilot actions aiming to contribute to the reduction of pollution, to enhance water quality, and to ensure that land-use practices and recreational activities can exist side by side without impacting public health. One of these actions is to identify and develop a common methodology for source-tracking fecal pollution, for regulatory purposes, over a wide geographical area in Europe. In order to do this the Department for Environment, Food and Rural Affairs, UK, sponsored the first international workshop on the subject. Key researchers from around the world were invited to attend to recommend the most appropriate method(s) for development and field trial in Europe. The meeting concluded that for the specific requirements of the ICReW project two methods should be developed and trialled: bacteroides genotyping and F+RNA coliphage genotyping. This article summarizes the reasons why these methods were chosen as the most appropriate for the circumstances of this particular project. The inherent challenges of establishing a pilot program to test the methods are outlined and recommendations were provided for the trial.INTERREG III

Collaborative, individualised lifestyle interventions are acceptable to people with first episode psychosis; a qualitative study

BackgroundThe adverse impact of unhealthy lifestyle choices and the prescription of antipsychotic medications contribute to weight gain, poor cardiovascular health and reduced life expectancy for people with psychosis. The present study aimed to explore the acceptability and perceived outcomes of a lifestyle intervention designed to prevent or reduce weight gain in people with first-episode psychosis.MethodsThis was a qualitative study using a data-driven approach. People recovering from first-episode psychosis recruited from UK early intervention services and taking part in the active arm of a randomised controlled trial of a lifestyle intervention (the InterACT trial), were interviewed using a semi-structured interview schedule. Interviews were transcribed verbatim and analysed using Framework Analysis.ResultsParticipants valued the collaborative and individualised approach taken by the intervention deliverers, and formed high quality relationships with them. Aspects of the intervention that were positively appraised included goal setting, social opportunities, and progress monitoring. Benefits of the intervention, including increased levels of exercise; improved diet and physical health; increased psychological wellbeing (e.g. confidence, self-esteem); and improved social relationships, were identified by participants, independent of actual weight loss.ConclusionsFuture interventions should ensure that workers have the skills to form high quality relationships with users, and to individualise the intervention according to users’ needs and preferences. Future trials that test healthy living interventions should consider supplementing physical outcome measures with wider psychosocial outcome assessments, in particular social relationship quality, psychological wellbeing, self-esteem and self-efficacy

The Mw7.8 2016 Kaikoura earthquake: surface fault rupture and seismic hazard context

We provide a summary of the surface fault ruptures produced by the Mw7.8 14 November 2016 Kaikōura earthquake, including examples of damage to engineered structures, transportation networks and farming infrastructure produced by direct fault surface rupture displacement. We also provide an overview of the earthquake in the context of the earthquake source model and estimated ground motions from the current (2010) version of the National Seismic Hazard Model (NSHM) for New Zealand. A total of 21 faults ruptured along a c.180 km long zone during the earthquake, including some that were unknown prior to the event. The 2010 version of the NSHM had considered multi-fault ruptures in the Kaikōura area, but not to the degree observed in the earthquake. The number of faults involved a combination of known and unknown faults, a mix of complete and partial ruptures of the known faults, and the non-involvement of a major fault within the rupture zone (i.e. the Hope Fault) makes this rupture an unusually complex event by world standards. However, the strong ground motions of the earthquake are consistent with the high hazard of the Kaikōura area shown in maps produced from the NSHM