Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

The dance goes on forever? Art schools, class and UK higher education

For most of the 20th century, the UK ‘art school’ was widely seen as an accessible alternative to University. In Art into Pop (1987), Simon Frith and Howard Horne revealed how this state-funded art and design training, linked to manufacturing industries and backed by relatively low or informal entry requirements, offered the prospect of social and economic uplift for hitherto marginalised working-class youth. More recently, however, while enrolments have expanded, art schools have become absorbed into conventional universities and the class profile, at least at the more prestigious colleges, has changed significantly. Simultaneously, art schools, together with other forms of higher education (HE) have been yoked to a broader public policy agenda of the ‘creative economy’ - one that often marginalises working-class people. This paper takes the changing nature of the art school as its starting point for discussion of class, higher education and the creative economy workforce