Gut Microbiota and Its Implications for Cardiovascular Diseases – a Review

Background: The symbiotic relationship between the gut microbiota and cardiovascular health has become a main point in contemporary research, offering valuable insights into the pathogenesis of cardiovascular diseases (CVDs). This review aims to comprehensively examine the bidirectional communication between gut microbial communities and the cardiovascular system, explaining the intricate mechanisms that connect gut dysbiosis to the initiation and progression of CVDs. Material and Methods: A systematic literature review was conducted to compile and analyze relevant studies investigating the impact of the gut microbiota on cardiovascular health. Emphasis was placed on explaining the molecular and physiological mechanisms underlying the interaction between gut microbes and cardiovascular function. Results: Our review confirmed evidence linking gut microbiota-derived metabolites, such as short-chain fatty acids, trimethylamine N-oxide and lipopolysaccharides to vascular function and inflammation. Additionally, we explored the modulation of host metabolism and immune responses by gut microbes, providing insights into their roles in atherosclerosis and hypertension. The review highlight the influence of diet and lifestyle on shaping the gut microbiome and, consequently, cardiovascular outcomes. Conclusions: Gut microbiota plays a crucial role in cardiovascular health and is involved in the start and development of various heart diseases. The identified molecular and physiological mechanisms highlight the need for complete understanding of the gut-cardiovascular axis. Moreover, the review emphasizes the potential of microbiota-targeted interventions, including probiotics and fecal microbiota transplantation, as innovative strategies for preventing and managing CVDs

Sorption of saturated and unsaturated hydrocarbons on selected coal sample from the Pniówek mine

Type, amount and composition of gases which form in rocks and coals during a metamorphism process depend on a number of factors in particular genetic type of original matter, way and conditions of its gathering, temperature, pressure and geological time. Sorption tests were done by the volumetric method, with the use of adsorption micro-burettes. Amajor advantage of the measurement set-up is that the surplus amounts of adsorbate can be used in experiments, which is of particular importance when handling sorbents with heterogeneous structure, such as hard coals. Sorbates used in the test program were the vapours of hexane, hex-1-ene, heptane, hept-1-ene, octane and benzene. Measurement results seem to corroborate the hypothesis that sorption of polar substance vapours is chiefly a surface process. Polarity of hard coals, mostly associated with the presence of reactive oxygen groups (nitrogen and sulphuric groups), largely affects the sorption of polar substances and in a most characteristic manner controls the sorption of apolar ones. In the case of the latter, sorption is induced by the action of the dispersive interaction force between the coal surface and the sorbate’s polar molecules. The pattern of sorption isotherms indicates that the presence of dual bond affects the sorbent-sorbate interactions and hence the sorption capacity of investigated coals

Experimental testing of methanol sorption on selected coal samples from Upper Silesian Basin

This paper summarises the results of methanol sorption on three selected coal samples from Polish collieries. These coals differ in terms of their degree of metamorphism (coal rank), petrography and elemental composition. It was found out that during the sorption of methanol, the sorption capacity is closely related to the structure of the coal surface and the amount of sorbed polar substance tends to decrease with the higher degree of metamorphism. Experimental data were plotted as isotherms. Empirical measurements were supported by thermodynamic analysis of aliphatic hydrocarbons sorption. The procedure is based on the Multisorption Model (MSM) designed for describing small molecules sorption in different types of carbonaceous materials (hard coals, lignites, active carbons)

CFD modeling of the catalyst oil slurry hydrodynamics in a high pressure and temperature as potential for biomass liquefaction

The paper presents the simulation of a catalyst-para n oil slurry hydrodynamics under high pressure and temperature in a convex bottom reactor with a Rushton turbine which was conducted with an application of computational fluid dynamics (CFD) modeling. An analysis to obtain a uniform distribution of solid catalyst particles suspended in para n oil was carried out as a potential for biomass liquefaction. The e ects of the particle diameter, bed density, liquid viscosity, and the initial solid loading on slurry hydrodynamics in high pressure and temperature behavior were investigated using the Eulerian–Eulerian two-fluid model and the standard k-" turbulence model. The main objective was to assess the performance in agitating highly concentrated slurries to obtain slurry velocity, concentration, the degree of homogeneity, and to examine their e ect on the mixing quality. The results of the analysis are applied to predicting the impact of the most e cient conditions on slurry suspension qualities as potential for biomass liquefaction

Rocznik Lubuski (t. 31, cz.1): Muzea i ochrona dziedzictwa kulturowego na Środkowym Nadodrzu

Muzea i Ochrona Dziedzictwa Kulturowego na Środkowym Nadodrzu