169 research outputs found

    IntOpt: in-band network telemetry optimization framework to monitor network slices using P4

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    The emergence of Network Functions Virtualization (NFV) is being heralded as an enabler of the recent technologies such as 5G/6G, IoT and heterogeneous networks. Existing NFV monitoring frameworks either do not have the capabilities to express the range of telemetry items needed to perform management or do not scale to large traffic volumes and rates. We present IntOpt, a scalable and expressive telemetry system designed for flexible NFV monitoring using active probing and P4. IntOpt allows us to specify monitoring requirements for individual service chain, which are mapped to telemetry item collection jobs that fetch the required telemetry items from P4 programmable data-plane elements. We propose mixed integer linear program (MILP) as well as a simulated annealing based random greedy (SARG) meta-heuristic approach to minimize the overhead due to active probing and collection of telemetry items. Using P4-FPGA, we benchmark the overhead for telemetry collection. Our numerical evaluation shows that the proposed approach can reduce monitoring overheads by 39% and monitoring delays by 57%. Such optimization may as well enable existing expressive monitoring frameworks to scale for larger real-time networks

    Stoics against stoics in Cudworth's "A Treatise of Freewill"

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    In his 'A Treatise of Freewill', Ralph Cudworth argues against Stoic determinism by drawing on what he takes to be other concepts found in Stoicism, notably the claim that some things are ‘up to us’ and that these things are the product of our choice. These concepts are central to the late Stoic Epictetus and it appears at first glance as if Cudworth is opposing late Stoic voluntarism against early Stoic determinism. This paper argues that in fact, despite his claim to be drawing on Stoic doctrine, Cudworth uses these terms with a meaning first articulated only later, by the Peripatetic commentator Alexander of Aphrodisias

    Stabilized Kuramoto-Sivashinsky system

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    A model consisting of a mixed Kuramoto - Sivashinsky - KdV equation, linearly coupled to an extra linear dissipative equation, is proposed. The model applies to the description of surface waves on multilayered liquid films. The extra equation makes its possible to stabilize the zero solution in the model, opening way to the existence of stable solitary pulses (SPs). Treating the dissipation and instability-generating gain in the model as small perturbations, we demonstrate that balance between them selects two steady-state solitons from their continuous family existing in the absence of the dissipation and gain. The may be stable, provided that the zero solution is stable. The prediction is completely confirmed by direct simulations. If the integration domain is not very large, some pulses are stable even when the zero background is unstable. Stable bound states of two and three pulses are found too. The work was supported, in a part, by a joint grant from the Israeli Minsitry of Science and Technology and Japan Society for Promotion of Science.Comment: A text file in the latex format and 20 eps files with figures. Physical Review E, in pres

    Self-testing for cancer: a community survey

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    <p>Abstract</p> <p>Background</p> <p>Cancer-related self-tests are currently available to buy in pharmacies or over the internet, including tests for faecal occult blood, PSA and haematuria. Self-tests have potential benefits (e.g. convenience) but there are also potential harms (e.g. delays in seeking treatment). The extent of cancer-related self-test use in the UK is not known. This study aimed to determine the prevalence of cancer-related self-test use.</p> <p>Methods</p> <p>Adults (n = 5,545) in the West Midlands were sent a questionnaire that collected socio-demographic information and data regarding previous and potential future use of 18 different self-tests. Prevalence rates were directly standardised to the England population. The postcode based Index of Multiple Deprivation 2004 was used as a proxy measure of deprivation.</p> <p>Results</p> <p>2,925 (54%) usable questionnaires were returned. 1.2% (95% CI 0.83% to 1.66%) of responders reported having used a cancer related self test kit and a further 36% reported that they would consider using one in the future. Logistic regression analyses suggest that increasing age, deprivation category and employment status were associated with cancer-related self-test kit use.</p> <p>Conclusion</p> <p>We conclude that one in 100 of the adult population have used a cancer-related self-test kit and over a third would consider using one in the future. Self-test kit use could alter perceptions of risk, cause psychological morbidity and impact on the demand for healthcare.</p

    Uptake of Workplace HIV Counselling and Testing: A Cluster-Randomised Trial in Zimbabwe

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    BACKGROUND: HIV counselling and testing is a key component of both HIV care and HIV prevention, but uptake is currently low. We investigated the impact of rapid HIV testing at the workplace on uptake of voluntary counselling and testing (VCT). METHODS AND FINDINGS: The study was a cluster-randomised trial of two VCT strategies, with business occupational health clinics as the unit of randomisation. VCT was directly offered to all employees, followed by 2 y of open access to VCT and basic HIV care. Businesses were randomised to either on-site rapid HIV testing at their occupational clinic (11 businesses) or to vouchers for off-site VCT at a chain of free-standing centres also using rapid tests (11 businesses). Baseline anonymised HIV serology was requested from all employees. HIV prevalence was 19.8% and 18.4%, respectively, at businesses randomised to on-site and off-site VCT. In total, 1,957 of 3,950 employees at clinics randomised to on-site testing had VCT (mean uptake by site 51.1%) compared to 586 of 3,532 employees taking vouchers at clinics randomised to off-site testing (mean uptake by site 19.2%). The risk ratio for on-site VCT compared to voucher uptake was 2.8 (95% confidence interval 1.8 to 3.8) after adjustment for potential confounders. Only 125 employees (mean uptake by site 4.3%) reported using their voucher, so that the true adjusted risk ratio for on-site compared to off-site VCT may have been as high as 12.5 (95% confidence interval 8.2 to 16.8). CONCLUSIONS: High-impact VCT strategies are urgently needed to maximise HIV prevention and access to care in Africa. VCT at the workplace offers the potential for high uptake when offered on-site and linked to basic HIV care. Convenience and accessibility appear to have critical roles in the acceptability of community-based VCT

    Prevalence of the use of cancer related self-tests by members of the public: a community survey

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    BACKGROUND: Self-tests are those where an individual can obtain a result without recourse to a health professional, by getting a result immediately or by sending a sample to a laboratory that returns the result directly. Self-tests can be diagnostic, for disease monitoring, or both. There are currently tests for more than 20 different conditions available to the UK public, and self-testing is marketed as a way of alerting people to serious health problems so they can seek medical help. Almost nothing is known about the extent to which people self-test for cancer or why they do this. Self-tests for cancer could alter perceptions of risk and health behaviour, cause psychological morbidity and have a significant impact on the demand for healthcare. This study aims to gain an understanding of the frequency of self-testing for cancer and characteristics of users. METHODS: Cross-sectional survey. Adults registered in participating general practices in the West Midlands Region, will be asked to complete a questionnaire that will collect socio-demographic information and basic data regarding previous and potential future use of self-test kits. The only exclusions will be people who the GP feels it would be inappropriate to send a questionnaire, for example because they are unable to give informed consent. Freepost envelopes will be included and non-responders will receive one reminder. Standardised prevalence rates will be estimated. DISCUSSION: Cancer related self-tests, currently available from pharmacies or over the Internet, include faecal occult blood tests (related to bowel cancer), prostate specific antigen tests (related to prostate cancer), breast cancer kits (self examination guide) and haematuria tests (related to urinary tract cancers). The effect of an increase in self-testing for cancer is unknown but may be considerable: it may affect the delivery of population based screening programmes; empower patients or cause unnecessary anxiety; reduce costs on existing healthcare services or increase demand to investigate patients with positive test results. It is important that more is known about the characteristics of those who are using self-tests if we are to determine the potential impact on health services and the public
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