5,870 research outputs found

    Transcription and the Pitch Angle of DNA

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    The question of the value of the pitch angle of DNA is visited from the perspective of a geometrical analysis of transcription. It is suggested that for transcription to be possible, the pitch angle of B-DNA must be smaller than the angle of zero-twist. At the zero-twist angle the double helix is maximally rotated and its strain-twist coupling vanishes. A numerical estimate of the pitch angle for B-DNA based on differential geometry is compared with numbers obtained from existing empirical data. The crystallographic studies shows that the pitch angle is approximately 38 deg., less than the corresponding zero-twist angle of 41.8 deg., which is consistent with the suggested principle for transcription.Comment: 7 pages, 3 figures; v2: minor modifications; v3: major modifications compared to v2. Added discussion about transcription, and reference

    Magnetic fluctuation power near proton temperature anisotropy instability thresholds in the solar wind

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    The proton temperature anisotropy in the solar wind is known to be constrained by the theoretical thresholds for pressure anisotropy-driven instabilities. Here we use approximately 1 million independent measurements of gyroscale magnetic fluctuations in the solar wind to show for the first time that these fluctuations are enhanced along the temperature anisotropy thresholds of the mirror, proton oblique firehose, and ion cyclotron instabilities. In addition, the measured magnetic compressibility is enhanced at high plasma beta (β∥≳1\beta_\parallel \gtrsim 1) along the mirror instability threshold but small elsewhere, consistent with expectations of the mirror mode. The power in this frequency (the 'dissipation') range is often considered to be driven by the solar wind turbulent cascade, an interpretation which should be qualified in light of the present results. In particular, we show that the short wavelength magnetic fluctuation power is a strong function of collisionality, which relaxes the temperature anisotropy away from the instability conditions and reduces correspondingly the fluctuation power.Comment: 4 pages, 4 figure

    Predictions for the First Parker Solar Probe Encounter

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    We examine Alfv\'en Wave Solar atmosphere Model (AWSoM) predictions of the first Parker Solar Probe (PSP) encounter. We focus on the 12-day closest approach centered on the 1st perihelion. AWSoM (van der Holst et al., 2014) allows us to interpret the PSP data in the context of coronal heating via Alfv\'en wave turbulence. The coronal heating and acceleration is addressed via outward-propagating low-frequency Alfv\'en waves that are partially reflected by Alfv\'en speed gradients. The nonlinear interaction of these counter-propagating waves results in a turbulent energy cascade. To apportion the wave dissipation to the electron and anisotropic proton temperatures, we employ the results of the theories of linear wave damping and nonlinear stochastic heating as described by Chandran et al. (2011). We find that during the first encounter, PSP was in close proximity to the heliospheric current sheet (HCS) and in the slow wind. PSP crossed the HCS two times, namely at 2018/11/03 UT 01:02 and 2018/11/08 UT 19:09 with perihelion occuring on the south of side of the HCS. We predict the plasma state along the PSP trajectory, which shows a dominant proton parallel temperature causing the plasma to be firehose unstable.Comment: 16 pages, 5 figures; accepted for publication in the Astrophysical Journal Letter

    GCR access to the Moon as measured by the CRaTER instrument on LRO

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    [1] Recent modeling efforts have yielded varying and conflicting results regarding the possibility that Earth\u27s magnetosphere is able to shield energetic particles of \u3e10 MeV at lunar distances. This population of particles consists of galactic cosmic rays as well as energetic particles that are accelerated by solar flares and coronal mass ejections. The Cosmic Ray Telescope for the Effects of Radiation (CRaTER) onboard the Lunar Reconnaissance Orbiter is in orbit about the Moon and is thus able to directly test these modeling results. Over the course of a month, CRaTER samples the upstream solar wind as well as various regions of Earth\u27s magnetotail. CRaTER data from multiple lunations demonstrate that Earth\u27s magnetosphere at lunar distances produces no measurable influence on energetic particle flux, even at the lowest energies (\u3e14 MeV protons) where any effect should be maximized. For particles with energies of 14–30 MeV, we calculate an upper limit (determined by counting statistics) on the amount of shielding caused by the magnetosphere of 1.7%. The high energy channel (\u3e500 MeV) provides an upper limit of 3.2%

    Stringent Phenomenological Investigation into Heterotic String Optical Unification

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    For the weakly coupled heterotic string (WCHS) there is a well-known factor of twenty conflict between the minimum string coupling unification scale, Lambda_H ~5x10^(17) GeV, and the projected MSSM unification scale, Lambda_U ~ 2.5x10^(16) GeV, assuming an intermediate scale desert (ISD). Renormalization effects of intermediate scale MSSM-charged exotics (ISME) (endemic to quasi-realistic string models) can resolve this issue, pushing the MSSM scale up to the string scale. However, for a generic string model, this implies that the projected Lambda_U unification under ISD is accidental. If the true unification scale is 5.0x10^(17) GeV, is it possible that illusionary unification at 2.5x10^(17) GeV in the ISD scenario is not accidental? If it is not, then under what conditions would the assumption of ISME in a WCHS model imply apparent unification at Lambda_U when ISD is falsely assumed? Geidt's "optical unification" suggests that Lambda_U is not accidental, by offering a mechanism whereby a generic MSSM scale Lambda_U < Lambda_H is guaranteed. A WCHS model was constructed that offers the possibility of optical unification, depending on the availability of anomaly-cancelling flat directions meeting certain requirements. This paper reports on the systematic investigation of the optical unification properties of the set of stringent flat directions of this model. Stringent flat directions can be guaranteed to be F-flat to all finite order (or to at least a given finite order consistent with electroweak scale supersymmetry breaking) and can be viewed as the likely roots of more general flat directions. Analysis of the phenomenology of stringent flat directions gives an indication of the remaining optical unification phenomenology that must be garnered by flat directions developed from them.Comment: standard latex, 18 pages of tex

    BIOH 458.01: Neuroscience Research Techniques

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    New measurements of total ionizing dose in the lunar environment

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    [1] We report new measurements of solar minimum ionizing radiation dose at the Moon onboard the Lunar Reconnaissance Orbiter (LRO) from June 2009 through May 2010. The Cosmic Ray Telescope for the Effects of Radiation (CRaTER) instrument on LRO houses a compact and highly precise microdosimeter whose design allows measurements of dose rates below 1 micro-Rad per second in silicon achieved with minimal resources (20 g, ∼250 milliwatts, and ∼3 bits/second). We envision the use of such a small yet accurate dosimeter in many future spaceflight applications where volume, mass, and power are highly constrained. As this was the first operation of the microdosimeter in a space environment, the goal of this study is to verify its response by using simultaneous measurements of the galactic cosmic ray ionizing environment at LRO, at L1, and with other concurrent dosimeter measurements and model predictions. The microdosimeter measured the same short timescale modulations in the galactic cosmic rays as the other independent measurements, thus verifying its response to a known source of minimum-ionizing particles. The total dose for the LRO mission over the first 333 days was only 12.2 Rads behind ∼130 mils of aluminum because of the delayed rise of solar activity in solar cycle 24 and the corresponding lack of intense solar energetic particle events. The dose rate in a 50 km lunar orbit was about 30 percent lower than the interplanetary rate, as one would expect from lunar obstruction of the visible sky
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