ヤマガタ ダイガク イガクブ フゾク ビョウイン ニオケル デングネツ ノ ソウキ ハッケン

Dengue fever (DF) is an acute febrile disease caused by dengue virus, which was re-emerged in tropical regions in the past 20 years. The numbers of imported DF were 6 to 44 per year in the recent Japan. We report a Japanese member of non-governmental organization (NGO) with dengue fever (DF). The patient developed sudden onset of high fever after returning to Japan, followed by rash and thrombocytopenia. DF was confirmed by isolation of dengue virus from serum, a positive reverse-transcriptase polymerase chain reaction (RT-PCR) test, and a high titer of IgM antibody to dengue virus. Dengue virus infection should be included in the differential diagnosis of the patients, developing high fever, skin rash, and thrombocytopenia after returning from endemic area.　Key words: dengue, fever, thrombocytopenia, lymphocyt