8 research outputs found
Diffuse Pan Bronchiolitis Presenting with Bronchiectasis: A Case Report
Diffuse Pan Bronchiolitis (DPB) is a peculiar airway disease with its pathogenesis enrooted in a complex interplay of various genetic and environmental factors. Airway inflammation, chronic airflow limitation and suppuratives in pulmonary infections are the distinctive features of this entity. It poses a close differential to
other frequently encountered pulmonary conditions like chronic bronchitis, emphysema, bronchiectasis and constrictive bronchiolitis. Deferment in diagnosis can culminate in irreversible airway remodeling and progressive respiratory failure. Hence a punctual recognition is vital. Macrolide group of drugs are prime
modality of therapy and the response to therapy is benignant. We herein describe a case of DPB with development of sequelae owing to its delayed detection
First Search for Axion-Like Particles in a Storage Ring Using a Polarized Deuteron Beam
Based on the notion that the local dark-matter field of axions or axion-like
particles (ALPs) in our Galaxy induces oscillating couplings to the spins of
nucleons and nuclei (via the electric dipole moment of the latter and/or the
paramagnetic axion-wind effect), we performed the first experiment to search
for ALPs using a storage ring. For that purpose, we used an in-plane polarized
deuteron beam stored at the Cooler Synchrotron COSY, scanning momenta near 970
MeV/c. This entailed a scan of the spin precession frequency. At resonance
between the spin precession frequency of deuterons and the ALP-induced EDM
oscillation frequency there will be an accumulation of the polarization
component out of the ring plane. Since the axion frequency is unknown, the
momentum of the beam and consequently the spin precession frequency were ramped
to search for a vertical polarization change that would occur when the
resonance is crossed. At COSY, four beam bunches with different polarization
directions were used to make sure that no resonance was missed because of the
unknown relative phase between the polarization precession and the axion/ALP
field. A frequency window of 1.5-kHz width around the spin precession frequency
of 121 kHz was scanned. We describe the experimental procedure and a test of
the methodology with the help of a radiofrequency Wien filter located on the
COSY ring. No ALP resonance was observed. As a consequence an upper limit of
the oscillating EDM component of the deuteron as well as its axion coupling
constants are provided.Comment: 25 pages, 24 figures, 7 tables, 67 reference
A Case Report of Severe Corneal Toxicity following 0.5% Topical Moxifloxacin Use
Moxifloxacin is a widely used topical antibiotic in various bacterial infections of the eye. Its safety and efficacy have been proved by many studies. We report a case of a rare adverse effect following its use. A 10-year-old female who had presented with acute bacterial conjunctivitis in both eyes with no corneal involvement was started on preservative-free 0.5% topical moxifloxacin four times a day. The child developed a severe form of corneal toxicity in both eyes with circumcorneal congestion and corneal edema following its use. The child's visual acuity had dropped from 20/20 to 20/400 in both the eyes. Topical moxifloxacin was discontinued, following which the cornea cleared dramatically and the visual acuity became normal. This case indicates that though rare, topical moxifloxacin can cause severe keratitis and that more studies need to be conducted to evaluate its safety
A Case Report of Vogt's Limbal Girdle and Retinitis Pigmentosa in a Thirteen-Year-Old Boy: A Rare and Unusual Association
Aim: To describe a rare case of Vogt's limbal girdle in a boy with retinitis pigmentosa. Methods: A 13-year-old boy from India presented to us with progressive diminution of vision and nyctalopia for 5 years. On examination, he had the characteristic features of retinitis pigmentosa with the fundus showing disc pallor, bony spicules and arteriolar attenuation. His anterior segment examination showed Vogt's limbal girdle in both eyes. Results: Vogt's limbal girdle is a corneal degeneration usually seen in elderly individuals. This is the first time it is seen in association with retinitis pigmentosa. It has also never been reported at such a young age. Conclusion: We report a rare case where Vogt's limbal girdle was observed in a 13-year-old boy with retinitis pigmentosa. This gives further insight into the pathogenesis of the disease
Transudative Effusion of Malignant Etiology: An Interesting Case Report
Pleural effusion is an entity perpetually encountered by physicians, having a panorama of etiologies. The occurrence of pleural effusion in a patient with malignancy adds multiple perspectives to the overall status of the patient in terms of symptomatology, staging, management and prognosis. Although effusion encountered in association with malignancies are conventionally exudative, transudative effusion can also manifest in certain singular circumstances. This conception is crucial to avoid misjudgments and delay in diagnosis. We hereby report an intriguing case of a transudative hemorrhagic pleural effusion in a patient with malignancy