Neurofeedback intervention in fibromyalgia syndrome; A randomized, controlled, rater blind clinical trial

We designed a randomized, rater blind study to assess the efficacy of EEG Biofeedback (Neurofeedback-NFB) in patients with fibromyalgia syndrome (FMS). Eighteen patients received twenty sessions of NFB-sensory motor rhythm (SMR) treatment (NFB group) during 4 weeks, and eighteen patients were given 10 mg per day escitalopram treatment (control group) for 8 weeks. Visual Analog Scales for pain and fatigue, Hamilton and Beck Depression and Anxiety Inventory Scales, Fibromyalgia Impact Questionnaire and Short Form 36 were used as outcome measures which were applied at baseline and 2nd, 4th, 8th, 16th, 24th weeks. Mean amplitudes of EEG rhythms (delta, theta, alpha, SMR, beta1 and beta2) and theta/SMR ratio were also measured in NFB group. All post-treatment measurements showed significant improvements in both of the groups (for all parameters p0.05 for all). However, theta/SMR ratio showed a significant decrease at 4th week compared to baseline in the NFB group (p<0.05). These data support the efficacy of NFB as a treatment for pain, psychological symptoms and impaired quality of life associated with fibromyalgia

Apple production and apple value chains in Europe

This paper presents an overview of the apple sector in nine major apple producing countries in Europe, in order to assess factors for the competitiveness of the national apple value chains and identify challenges for the future development of the sector. Based on international and national statistical data and expert assessment, key characteristics of apple production and value chains are analyzed. For each country, a brief description of the development of apple production and acreage over the past ten years, farm size distribution, level of production technology and main market channels is presented, followed by a discussion of differences and similarities. Results show a diverse picture of the apple sectors in Europe. Similarities are observed in the existence of regional production clusters and a generally small farm size. Differences are found in the technology level, with a broad range of very traditional extensive production systems up to highly intensified orchards with high tree density. All countries experienced high fluctuation in apple production quantities over the past years, mainly due to weather events, particularly spring frost and drought, and climate risks are expected to increase in the future, leading to increasing costs for mitigation measure