Interdependencies related to Attention Restoration for Mental fatigue: A scoping review

This paper investigates and gathers data on the causal constraint rehabilitation of mental fatigue linked with attention restoration (ART) components that correlate with the scale of perceived setting interdependencies (PSI) to identify the relationship between the component of ART and the scale of PSI that affect mental fatigue recovery by using scoping review, searching keywords from international literature from 1979 to 2022 in a relevant database and snowballing method in the references list to get a recent paper that is related. Relationships were conceptualized using perceived setting interdependencies (PSI) indicators that identified the relationship between attention restoration and mental fatigue. Keywords: Behavior setting; Interdependence; Mental fatigue;  Attention Restoration eISSN: 2398-4287 © 2023. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under the responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians), and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v8i23.4389

Response to Dengue virus infections altered by cytokine-like substances from mosquito cell cultures

<p>Abstract</p> <p>Background</p> <p>With both shrimp and commercial insects such as honey bees, it is known that stable, persistent viral infections characterized by absence of disease can sometimes shift to overt disease states as a result of various stress triggers and that this can result in serious economic losses. The main research interest of our group is to understand the dynamics of stable viral infections in shrimp and how they can be destabilized by stress. Since there are no continuous cell lines for crustaceans, we have used a C6/36 mosquito cell line infected with Dengue virus to test hypotheses regarding these interactions. As a result, we accidentally discovered two new cytokine-like substances in 5 kDa extracts from supernatant solutions of acutely and persistently infected mosquito cells.</p> <p>Results</p> <p>Naïve C6/36 cells were exposed for 48 h to 5 kDa membrane filtrates prepared from the supernatant medium of stable C6/36 mosquito cell cultures persistently-infected with Dengue virus. Subsequent challenge of naïve cells with a virulent stock of Dengue virus 2 (DEN-2) and analysis by confocal immunofluorescence microscopy using anti-DEN-2 antibody revealed a dramatic reduction in the percentage of DEN-2 infected cells when compared to control cells. Similar filtrates prepared from C6/36 cells with acute DEN-2 infections were used to treat stable C6/36 mosquito cell cultures persistently-infected with Dengue virus. Confocal immunofluorescence microscopy revealed destabilization in the form of an apoptosis-like response. Proteinase K treatment removed the cell-altering activities indicating that they were caused by small polypeptides similar to those previously reported from insects.</p> <p>Conclusions</p> <p>This is the first report of cytokine-like substances that can alter the responses of mosquito cells to Dengue virus. This simple model system allows detailed molecular studies on insect cytokine production and on cytokine activity in a standard insect cell line.</p

Persistent, triple-virus co-infections in mosquito cells

<p>Abstract</p> <p>Background</p> <p>It is known that insects and crustaceans can carry simultaneous, active infections of two or more viruses without showing signs of disease, but it was not clear whether co-infecting viruses occupied the same cells or different cells in common target tissues. Our previous work showed that successive challenge of mosquito cell cultures followed by serial, split-passage resulted in stabilized cultures with 100% of the cells co-infected with Dengue virus (DEN) and an insect parvovirus (densovirus) (DNV). By addition of Japanese encephalitis virus (JE), we tested our hypothesis that stable, persistent, triple-virus co-infections could be obtained by the same process.</p> <p>Results</p> <p>Using immunocytochemistry by confocal microscopy, we found that JE super-challenge of cells dually infected with DEN and DNV resulted in stable cultures without signs of cytopathology, and with 99% of the cells producing antigens of the 3 viruses. Location of antigens for all 3 viruses in the triple co-infections was dominant in the cell nuclei. Except for DNV, this differed from the distribution in cells persistently infected with the individual viruses or co-infected with DNV and DEN. The dependence of viral antigen distribution on single infection or co-infection status suggested that host cells underwent an adaptive process to accommodate 2 or more viruses.</p> <p>Conclusions</p> <p>Individual mosquito cells can accommodate at least 3 viruses simultaneously in an adaptive manner. The phenomenon provides an opportunity for genetic exchange between diverse viruses and it may have important medical and veterinary implications for arboviruses.</p

Effect of Kao-Ta (9-Square Step Exercise) and Kao-Ten (9-Square Dance Exercise) on Balance Rehabilitation in Patients with Balance Disorders

Objective: To study the effect of Kao-ta (9-square step exercise) and Kao-ten (9-square dance exercise) on balance improvement in patients with balance disorders. Methods: This prospective pilot study in patients with balance disorders was conducted at the outpatient clinic, Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand from December 2015 to December 2016. Patients diagnosed by clinical symptoms and at least one abnormal condition on posturography were taught how to perform Kao-ta and Kao-ten exercise. Participants were provided with the equipment necessary to create a nine square grid at home. They were instructed to perform 3 minutes of Kao-ta followed by 2 minutes of Kao-ten twice per day for at least 45 days in an 8-week period. Posturography and visual analogue scale (VAS) of balance symptom severity were compared between before and after exercise program.  Results: Eleven patients with balance disorders were included. The mean age was 57.2±12.9 years (range: 33-70), and all patients were women. The average composite equilibrium score at baseline was 64.4±8.1. After 8 weeks of Kao-ta and Kao-ten, the average composite equilibrium score increased to 73.8±10.2 (p<0.01). The median (P25, P75) of the abnormal equilibrium score condition decreased from 2 (1, 3) at baseline to 1 (0, 2) after 8 weeks (p=0.016). The median VAS of balance symptom severity decreased from 4 (3, 6) at baseline to 2 (0.2, 5.5) after 8 weeks (p=0.028). Conclusion: Kao-ta and Kao-ten exercise can improve symptoms in patients with balance disorders after 8 weeks of exercise

Hearing and Balance Survey in Thai Elders

Objective: To survey hearing and balance problems of a sampling group of Thai elders in the central region of Thailand. Methods: A population study was people aged 60 and over who agreed to join the survey at the 14 elderly social associations. The questionnaires were used as a self-report for hearing and balance problems. After ears examination by ENT specialists, the participants underwent air-conduction audiometry for hearing screening. Results: 828 participants 259 (31.3%) males and 569 (68.7%) females, age ranged from 60 to 97 (median=68, mean ± SD = 69.65 ± 6.89 years), had completed screening program for hearing and balance problems using both questionnaires and examinations. There was a statistically significant correlation between self-report hearing loss and severe or profound hearing loss in both ears (P <0.05). All age groups reported dizziness and vertigo but the elderly over 75 years reported more falls with a statistical significance (P=0.021). The elderly who did not report dizziness or vertigo had a1.1-1.6 times higher fall histories than those who reported (P <0.001). The participants who had hypertension and dyslipidemia reported more falls with statistical significances (P=0.025 and 0.036 respectively). Conclusion: Our hearing and balance questionnaires may be used as a tool for screening at a primary care for the elderly > 70 years old especially in those with underlying diseases. Hearing and balance screening will provide early detection and primary intervention to minimize the negative impact in the elderly’s daily life

Effect of Kao-Ta (9-Square Step Exercise) and Kao-Ten (9-Square Dance Exercise) on Balance Rehabilitation in Patients with Balance Disorders

Objective: To study the effect of Kao-ta (9-square step exercise) and Kao-ten (9-square dance exercise) on balance improvement in patients with balance disorders. Methods: This prospective pilot study in patients with balance disorders was conducted at the outpatient clinic, Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand from December 2015 to December 2016. Patients diagnosed by clinical symptoms and at least one abnormal condition on posturography were taught how to perform Kao-ta and Kao-ten exercise. Participants were provided with the equipment necessary to create a nine square grid at home. They were instructed to perform 3 minutes of Kao-ta followed by 2 minutes of Kao-ten twice per day for at least 45 days in an 8-week period. Posturography and visual analogue scale (VAS) of balance symptom severity were compared between before and after exercise program. Results: Eleven patients with balance disorders were included. The mean age was 57.2±12.9 years (range: 33-70), and all patients were women. The average composite equilibrium score at baseline was 64.4±8.1. After 8 weeks of Kao-ta and Kao-ten, the average composite equilibrium score increased to 73.8±10.2 (p<0.01). The median (P25, P75) of the abnormal equilibrium score condition decreased from 2 (1, 3) at baseline to 1 (0, 2) after 8 weeks (p=0.016). The median VAS of balance symptom severity decreased from 4 (3, 6) at baseline to 2 (0.2, 5.5) after 8 weeks (p=0.028). Conclusion: Kao-ta and Kao-ten exercise can improve symptoms in patients with balance disorders after 8 weeks of exercise

Inducible viral receptor, A possible concept to induce viral protection in primitive immune animals

A pseudolysogen (PL) is derived from the lysogenic Vibrio harveyi (VH) which is infected with the VHS1 (Vibrio harveyi Siphoviridae-like 1) bacteriophage. The lysogenic Vibrio harveyi undergoes an unequivalent division of the extra-chromosomal VHS1 phage genome and its VH host chromosome and produces a true lysogen (TL) and pseudolysogen (PL). The PL is tolerant to super-infection of VHS1, as is of the true lysogen (TL), but the PL does not contain the VHS1 phage genome while the TL does. However, the PL can become susceptible to VHS1 phage infection if the physiological state of the PL is changed. It is postulated that this is due to a phage receptor molecule which can be inducible to an on-and-off regulation influence by an alternating condition of the bacterial host cell. This characteristic of the PL leads to speculate that this phenomenon can also occur in high organisms with low immunity such as shrimp. This article proposes a hypothesis that the viral receptor molecule on the target cell can play a crucial role in which the invertebrate aquaculture animals can become tolerant to viral infection. A possible mechanism may be that the target cell disrupts the viral receptor molecule to prevent super infection. This concept can explain a mechanism for the prevention of viral infection in invertebrate animals which do not have acquired immunity in response to pathogens. It can guide us to develop a mechanism of immunity to viral infection in low-evolved-immune animals. Also, it can be an additional mechanism that exists in high immune organism, as in human for the prevention of viral infectio

The scope of the crustacean immune system for disease control

The culture or wild capture of marine and freshwater shellfish, including crustaceans, is without doubt a key source of protein for a burgeoning world population. Historically the expansion of aquaculture has, however, been accompanied by the increased incidence of economically significant diseases, most notably of viral and bacterial origin. Since the late 1970s great progress has been made in our understanding of the generalized protostome innate immune system. Distinct pathways, pathogen receptor proteins and effector molecules have since been identified that are not ancestral or homologous to those of the deuterostomes, including vertebrates. Within the past decade progress has accelerated with the rapid characterisation of new classes of recognition proteins, immune effectors and regulatory pathways. This paper provides a broad overview of our current understanding of invertebrate immunology, taking the crustacean decapod immune system as its focus. Recent developments in the field are described briefly and their implications and potential considered. These advances offer fundamental new insights in our efforts to understand disease in cultured populations and also to develop knowledge of environmental effects on host/pathogen interactions within a fishery context. Of course, challenges do remain, including the lack of an immortal cell line and the limited publically-available genomic resources. These are considered in this review as priorities for future research effort. With the continued application of more insightful technologies, coupled with associated investment, it is expected that the speed at which some of these issues are resolved will accelerate

Hearing and Balance Survey in Thai Elders

Objective: To survey hearing and balance problems of a sampling group of Thai elders in the central region of Thailand. Methods: A population study was people aged 60 and over who agreed to join the survey at the 14 elderly social associations. The questionnaires were used as a self-report for hearing and balance problems. After ears examination by ENT specialists, the participants underwent air-conduction audiometry for hearing screening. Results:828 participants (259 (31.3%) males and 569 (68.7%) females, age ranged from 60 to 97 (median=68, mean ± SD = 69.65 ± 6.89 years), had completed screening program for hearing and balance problems using both questionnaires and examinations. There was a statistically significant correlation between self-report hearing loss and severe or profound hearing loss in both ears (P <0.05). All age groups reported dizziness and vertigo but the elderly over 75 years reported more falls with a statistical significance (P=0.021). The elderly who did not report dizziness or vertigo had a1.1-1.6 times higher fall histories than those who reported (P <0.001). The participants who had hypertension and dyslipidemia reported more falls with statistical significances (P=0.025 and 0.036 respectively). Conclusion: Our hearing and balance questionnaires may be used as a tool for screening at a primary care for the elderly > 70 years old especially in those with underlying diseases. Hearing and balance screening will provide early detection and primary intervention to minimize the negative impact in the elderly’s daily life