Probing non-linear MHD stability of the EDA H-mode in ASDEX Upgrade

Regimes of operation in tokamaks that are devoid of large ELMs have to be better understood to extrapolate their applicability to reactor-relevant devices. This paper describes non-linear extended MHD simulations that use an experimental equilibrium from an EDA H-mode in ASDEX Upgrade. Linear ideal MHD analysis indicates that the operational point lies slightly inside of the stable region. The non-linear simulations with the visco-resistive extended MHD code, JOREK, sustain non-axisymmetric perturbations that are linearly most unstable with toroidal mode numbers of n = \{6 \dots 9\}, but non-linearly higher and lower n become driven and the low-n become dominant. The poloidal mode velocity during the linear phase is found to correspond to the expected velocity for resistive ballooning modes. The perturbations that exist in the simulations have somewhat smaller poloidal wavenumbers (k_{\theta} \sim 0.1 to 0.5 cm^{-1} ) than the experimental expectations for the quasi-coherent mode in EDA, and cause non-negligible transport in both the heat and particle channels. In the transition from linear to non-linear phase, the mode frequency chirps down from approximately 35 kHz to 13 kHz, which corresponds approximately to the lower end of frequencies that are typically observed in EDA H-modes in ASDEX Upgrade

PREDICTORS OF HYPERTENSION

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74570/1/j.1749-6632.1978.tb25565.x.pd

Dwelling, house and home: towards a home-led perspective on dementia care

“Home” is well known from everyday experience, plays a crucial role in all kinds of narratives about human life, but is hardly ever systematically dealt with in the philosophy of medicine and health care. The notion of home is ambiguous, is often used in a metaphorical way, and is closely related to concepts such as house and dwelling. In this paper the phenomenon of home is explored by means of some phenomenological writings of Heidegger, Bollnow, Bachelard and Levinas. Common in their views is that being at home and dwelling mean something more fundamental than an activity we do along with other activities, such as working and travelling. Dwelling, building a house and being at home are fundamental aspects of human existence. Being human is dwelling. While exploring the relevance of this phenomenological perspective for medical theory and practice, the focus is on the care of people suffering from dementia

Designing a Good Life: A Matrix for the Technological Mediation of Morality

Technologies fulfill a social role in the sense that they influence the moral actions of people, often in unintended and unforeseen ways. Scientists and engineers are already accepting much responsibility for the technological, economical and environmental aspects of their work. This article asks them to take an extra step, and now also consider the social role of their products. The aim is to enable engineers to take a prospective responsibility for the future social roles of their technologies by providing them with a matrix that helps to explore in advance how emerging technologies might plausibly affect the reasons behind people’s (moral) actions. On the horizontal axis of the matrix, we distinguished the three basic types of reasons that play a role in practical judgment: what is the case, what can be done and what should be done. On the vertical axis we distinguished the morally relevant classes of issues: stakeholders, consequences and the good life. To illustrate how this matrix may work in practice, the final section applies the matrix to the case of the Google PowerMeter

Personality traits and behavioral patterns associated with systolic blood pressure levels in college males

1. 1. Seventy-four young white male college students (out of an original pool of 800 examined) were selected for having high or low systolic readings taken on a registration line. These students were then classified according to their paired casual, usual, and sustained levels of systolic blood pressure. Of 21 persons with a high paired casual systolic blood pressure (two independent determinations in excess of 140 mm Hg), 16 were also characterized as belonging to a `usual high' group (blood pressure in excess of 131 mm on resting and repeated home readings). A `sustained' high blood pressure group (n = 11) was further obtained by selecting those who were `high' on their paired casual and their `usual' blood pressure levels. These blood pressure patterns were then related with self ratings on the Cattell 16 PF questionnaire.2. 2. A consistent elevation to the upper range of normal in the systolic blood pressure of these college males was associated with `submissiveness' and `sensitivity' as defined by Cattell's 16 PF questionnaire. Subjects with `high paired casual' systolic blood pressures described themselves as motivated to obtain social contacts, but in a `sensitive' and `anxious' manner.3. 3. Subjects who were later selected for having a single high systolic blood pressure reading taken on first entering the physician's office (their second casual reading) tended more frequently to yield in an argument and then afterwards to change their private opinions toward agreement with partners who had an initially low systolic reading.4. 4. Whereas obesity was highly correlated with higher systolic levels, the psychological correlates of obesity were different from those related to elevated `casual' or `sustained' blood pressure. Obese subjects in this population appeared to be physically active, and more confident, though somewhat anxious under the stress of school examinations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32127/1/0000180.pd

Revisiting and modelling the woodland farming system of the early Neolithic Linear Pottery Culture (LBK), 5600–4900 B.C

International audienceThis article presents the conception and the conceptual results of a modelling representation of the farming systems of the Linearbandkeramik Culture (LBK). Assuming that there were permanent fields (PF) then, we suggest four ways that support the sustainability of such a farming system over time: a generalized pollarding and coppicing of trees to increase the productivity of woodland areas for foddering more livestock, which itself can then provide more manure for the fields, a generalized use of pulses grown together with cereals during the same cropping season, thereby reducing the needs for manure. Along with assumptions limiting bias on village and family organizations, the conceptual model which we propose for human environment in the LBK aims to be sustainable for long periods and can thereby overcome doubts about the PFs hypothesis for the LBK farming system. Thanks to a reconstruction of the climate of western Europe and the consequent vegetation pattern and productivity arising from it, we propose a protocol of experiments and validation procedures for both testing the PFs hypothesis and defining its eco-geographical area

Bioavailability in soils

The consumption of locally-produced vegetables by humans may be an important exposure pathway for soil contaminants in many urban settings and for agricultural land use. Hence, prediction of metal and metalloid uptake by vegetables from contaminated soils is an important part of the Human Health Risk Assessment procedure. The behaviour of metals (cadmium, chromium, cobalt, copper, mercury, molybdenum, nickel, lead and zinc) and metalloids (arsenic, boron and selenium) in contaminated soils depends to a large extent on the intrinsic charge, valence and speciation of the contaminant ion, and soil properties such as pH, redox status and contents of clay and/or organic matter. However, chemistry and behaviour of the contaminant in soil alone cannot predict soil-to-plant transfer. Root uptake, root selectivity, ion interactions, rhizosphere processes, leaf uptake from the atmosphere, and plant partitioning are important processes that ultimately govern the accumulation ofmetals and metalloids in edible vegetable tissues. Mechanistic models to accurately describe all these processes have not yet been developed, let alone validated under field conditions. Hence, to estimate risks by vegetable consumption, empirical models have been used to correlate concentrations of metals and metalloids in contaminated soils, soil physico-chemical characteristics, and concentrations of elements in vegetable tissues. These models should only be used within the bounds of their calibration, and often need to be re-calibrated or validated using local soil and environmental conditions on a regional or site-specific basis.Mike J. McLaughlin, Erik Smolders, Fien Degryse, and Rene Rietr

Role of Pleiotropy in the Evolution of a Cryptic Developmental Variation in Caenorhabditis elegans

Using vulval phenotypes in Caenorhabditis elegans, the authors show that cryptic genetic variation can evolve through selection for pleiotropic effects that alter fitness, and identify a cryptic variant that has conferred enhanced fitness on domesticated worms under laboratory conditions