100 research outputs found
Potent Inhibition of Cicatricial Contraction in Proliferative Vitreoretinal Diseases by Statins
OBJECTIVE—Despite tremendous progress in vitreoretinal surgery, certain postsurgical complications limit the success in the treatment of proliferative vitreoretinal diseases (PVDs), such as proliferative diabetic retinopathy (PDR) and proliferative vitreoretinopathy (PVR). One of the most significant complications is the cicatricial contraction of proliferative membranes, resulting in tractional retinal detachment and severe vision loss. Novel pharmaceutical approaches are thus urgently needed for the management of these vision-threatening diseases. In the current study, we investigated the inhibitory effects of statins on the progression of PVDs
Comparative effect of glucagon and isoproterenol on hepatic glycogenolysis and glycolysis in isolated perfused liver
Bifurcation of the East India Coastal Current east of Sri Lanka
The East India Coastal Current (EICC) flows equatorward during October–December carrying low salinity water from the Bay of Bengal en route. Using results from a high resolution ocean general circulation model, satellite altimeter data, Argo float profiles and ocean color images we show that the EICC bifurcates east of Sri Lanka. One part continues along the coast of Sri Lanka but the major part of the EICC, called here as the East Sri Lanka Jet (ESLJ) flows eastward into the Bay of Bengal. As a result of this bifurcation, there is offshore transport of chlorophyll a rich low salinity water from the coast of Sri Lanka. Altimeter data from 1993–2004 show that the bifurcation occurred every year except during the Indian Ocean Dipole (IOD) years of 1994 and 1997. The bifurcation occurs when an anticyclonic eddy that propagates westward ahead of a downwelling Rossby wave front impinges on the Sri Lanka coast. This new finding suggests that the main route of the low salinity water from the Bay of Bengal into the southeastern Arabian Sea may not be along the coast around Sri Lanka but through the Winter Monsoon Current
Combined 17α-hydroxylase/17,20-lyase deficiency caused by heterozygous stop codons in the cytochrome P450 17α-hydroxylase gene
A deficiency in CDw52 (CAMPATH-1 antigen) of paroxysmal nocturnal hemoglobinuria lymphocytes [letter]
A deficiency in CDw52 (CAMPATH-1 antigen) of paroxysmal nocturnal hemoglobinuria lymphocytes [letter]
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