Baryon chiral perturbation theory transferred to hole-doped antiferromagnets on the honeycomb lattice

A systematic low-energy effective field theory for hole-doped antiferromagnets on the honeycomb lattice is constructed. The formalism is then used to investigate spiral phases in the staggered magnetization as well as the formation of two-hole bound states.Comment: Talk delivered by C.P. Hofmann at the XIII Mexican Workshop on Particles and Fields, October 19-26, 2011, Leon, Guanajuato, Mexico; 15 pages, 7 figure

Staphylococcal enterotoxin B (SEB) activates TCR- and CD28-mediated inflammatory signals in the absence of MHC class II molecules

The inflammatory activity of staphylococcal enterotoxin B (SEB) relies on its capacity to trigger polyclonal T‐cell activation by binding both T‐cell receptor (TCR) and costimulatory receptor CD28 on T cells and MHC class II and B7 molecules on antigen presenting cells (APC). Previous studies highlighted that SEB may bind TCR and CD28 molecules independently of MHC class II, yet the relative contribution of these interactions to the pro‐inflammatory function of SEB remained unclear. Here, we show that binding to MHC class II is dispensable for the inflammatory activity of SEB, whereas binding to TCR, CD28 and B7 molecules is pivotal, in both human primary T cells and Jurkat T cell lines. In particular, our finding is that binding of SEB to B7 molecules suffices to trigger both TCR‐ and CD28‐mediated inflammatory signalling. We also provide evidence that, by strengthening the interaction between CD28 and B7, SEB favours the recruitment of the TCR into the immunological synapse, thus inducing lethal inflammatory signallin

Schroedingers equation with gauge coupling derived from a continuity equation

We consider a statistical ensemble of particles of mass m, which can be described by a probability density \rho and a probability current \vec{j} of the form \rho \nabla S/m. The continuity equation for \rho and \vec{j} implies a first differential equation for the basic variables \rho and S. We further assume that this system may be described by a linear differential equation for a complex state variable \chi. Using this assumptions and the simplest possible Ansatz \chi(\rho,S) Schroedingers equation for a particle of mass m in an external potential V(q,t) is deduced. All calculations are performed for a single spatial dimension (variable q) Using a second Ansatz \chi(\rho,S,q,t) which allows for an explict q,t-dependence of \chi, one obtains a generalized Schroedinger equation with an unusual external influence described by a time-dependent Planck constant. All other modifications of Schroeodingers equation obtained within this Ansatz may be eliminated by means of a gauge transformation. Thus, this second Ansatz may be considered as a generalized gauging procedure. Finally, making a third Ansatz, which allows for an non-unique external q,t-dependence of \chi, one obtains Schroedingers equation with electromagnetic potentials \vec{A}, \phi in the familiar gauge coupling form. A possible source of the non-uniqueness is pointed out.Comment: 25 pages, no figure

Limitations on the superposition principle: superselection rules in non-relativistic quantum mechanics

The superposition principle is a very basic ingredient of quantum theory. What may come as a surprise to many students, and even to many practitioners of the quantum craft, is tha superposition has limitations imposed by certain requirements of the theory. The discussion of such limitations arising from the so-called superselection rules is the main purpose of this paper. Some of their principal consequences are also discussed. The univalence, mass and particle number superselection rules of non-relativistic quantum mechanics are also derived using rather simple methods.Comment: 22 pages, no figure

Inclusive pion and eta production in p+Nb collisions at 3.5 GeV beam energy

Data on inclusive pion and eta production measured with the dielectron spectrometer HADES in the reaction p+93Nb at a kinetic beam energy of 3.5 GeV are presented. Our results, obtained with the photon conversion method, supplement the rather sparse information on neutral meson production in proton-nucleus reactions existing for this bombarding energy regime. The reconstructed e+e-e+e- transverse-momentum and rapidity distributions are confronted with transport model calculations, which account fairly well for both pi0 and eta production.Comment: 12 pages, 9 figures, submitted to Physical Review

Searching a Dark Photon with HADES

We present a search for the e+e- decay of a hypothetical dark photon, also names U vector boson, in inclusive dielectron spectra measured by HADES in the p (3.5 GeV) + p, Nb reactions, as well as the Ar (1.756 GeV/u) + KCl reaction. An upper limit on the kinetic mixing parameter squared epsilon^{2} at 90% CL has been obtained for the mass range M(U) = 0.02 - 0.55 GeV/c2 and is compared with the present world data set. For masses 0.03 - 0.1 GeV/c^2, the limit has been lowered with respect to previous results, allowing now to exclude a large part of the parameter region favoured by the muon g-2 anomaly. Furthermore, an improved upper limit on the branching ratio of 2.3 * 10^{-6} has been set on the helicity-suppressed direct decay of the eta meson, eta-> e+e-, at 90% CL

Binding of Superantigen Toxins into the CD28 Homodimer Interface Is Essential for Induction of Cytokine Genes That Mediate Lethal Shock

Bacterial superantigen toxins bind directly to the dimer interface of CD28, the principal co-stimulatory receptor, to induce a lethal cytokine storm, and peptides that prevent this binding can suppress superantigen lethality

A genome-wide resource for the analysis of protein localisation in Drosophila

The Drosophila genome contains >13000 protein-coding genes, the majority of which remain poorly investigated. Important reasons include the lack of antibodies or reporter constructs to visualise these proteins. Here, we present a genome-wide fosmid library of 10000 GFP-tagged clones, comprising tagged genes and most of their regulatory information. For 880 tagged proteins, we created transgenic lines, and for a total of 207 lines, we assessed protein expression and localisation in ovaries, embryos, pupae or adults by stainings and live imaging approaches. Importantly, we visualised many proteins at endogenous expression levels and found a large fraction of them localising to subcellular compartments. By applying genetic complementation tests, we estimate that about two-thirds of the tagged proteins are functional. Moreover, these tagged proteins enable interaction proteomics from developing pupae and adult flies. Taken together, this resource will boost systematic analysis of protein expression and localisation in various cellular and developmental contexts