Regulated progression of B lymphocyte differentiation from cultured fetal liver.

Lymphoid fetal liver cultures (LFLC) are long-term, nontransformed cultures of early B lymphoid lineage cells which appear developmentally blocked at the pre-B stage in vitro. When injected into severe combined immunodeficient (SCID) mice, cells from LFLC could reconstitute splenic B lymphocytes and serum IgM. T lymphocyte reconstitution was not observed and serum IgG levels were very low. IgG3 was the predominant gamma subisotype in the serum of the LFLC-reconstituted mice, indicating impaired class switching in these B lymphocytes. When thymocytes were coinjected with LFLC, the B lymphocytes were able to class switch fully and respond to T-dependent antigens. These serological responses were heterogeneous. This experimental system allows separation of three B lymphocyte developmental stages: early differentiation in vitro, progression to IgM secretion in vivo, and late differentiation dependent upon mature T lymphocytes in vivo. The unique advantage of this system is the ability to regulate the B lymphocyte developmental pathway in a defined, stepwise manner

A versatile telemetric system based on mixed Internet and wireless transmission

A novel telemetric technique for carrying data from distant field stations to a central point, upgrading an existing high cost network, is presented. This new technique can be applied for educational purposes since it enables students to overview the installation, operation and maintenance of a high tech complex network, spread in distances of the order of several hundreds of kilometres. The proposed technique followed by the appropriate visual aids can help students to understand better long distance data transmission

Use of 3G mobile phone links for teleconsultation between a moving ambulance and a hospital base station

The importance of this paper lays in its suggestion: minimise the time for the initial treatment of a patient. As soon as an ambulance receives a patient, a videoconferencing session can be initiated between the moving vehicle and a base station in a hospital where a medical consultant resides. The communication link is implemented using 3G networks. Effectively, the use of such a system can decrease fatality on patients being transferred to A&E, as expert opinion can be obtained straight away. This paper was repeatedly cited in IEEE papers and formed the basis for an EPSRC proposal that was recently submitted

3G networks in emergency telemedicine - An in-depth evaluation & analysis

The evolution of telecommunications technologies in connection with the robustness and the fidelity these new systems provide, have opened up many new horizons as regards the provision of healthcare and the quality of service from the side of the experts to that of the patients. The purpose of this paper is to evaluate the third generation telecommunications systems that are only recently being deployed in Europe, as well as argue on why a transition from 2G and 2.5G to 3G telecommunications systems could prove to be crucial, especially in relation to emergency telemedicine. The experimental results of the use of these systems are analyzed, the implementation of a tele-consultation unit is presented and their exploitation capabilities are explored

Using HSPA to improve the telemedical links on a moving ambulance

As the demand for faster and more effective health care increases, there is a growing need to establish mobile, high-speed communications between a moving ambulance and a consultation point (usually a hospital). The recent addition of HSPA (HSDPA and HSUPA) into the UMTS suite provides higher bandwidth and reduced delays, making this choice ideal for real-time telemedical applications. In this paper, we will describe a set of scenarios that took place in a typical large city area, along with their equivalent results: a moving ambulance was linked with a consultation station using HSPA and several videoconferencing sessions were initiated. Best-case, worst-case and average scenarios were recorded. Furthermore, in areas where the UMTS reception was marginal, a repeater was placed on top of the vehicle to boost up the signal power and thus maintain the higher bandwidth. Finally, treating doctors were asked to evaluate the effectiveness of this system’s outputs, based on a variety of objective and subjective criteria

Role of high-spin hyperon resonances in the reaction of γp→K+K+Ξ−\gamma p \to K^+ K^+ \Xi^-

The recent data taken by the CLAS Collaboration at the Thomas Jefferson National Accelerator Facility for the reaction of $\gamma p \to K^+ K^+ \Xi^-$ are reanalyzed within a relativistic meson-exchange model of hadronic interactions. The present model is an extension of the one developed in an earlier work by Nakayama, Oh, and Haberzettl [Phys. Rev. C 74, 035205 (2006)]. In particular, the role of the spin-5/2 and -7/2 hyperon resonances, which were not included in the previous model, is investigated in the present study. It is shown that the contribution of the $\Sigma(2030)$ hyperon having spin-7/2 and positive parity has a key role to bring the model predictions into a fair agreement with the measured data for the $K^+\Xi^-$ invariant mass distribution.Comment: 8 pages, 3 figures, REVTe