5,859 research outputs found
Spatial effects of Fano resonance in local tunneling conductivity in vicinity of impurity on semiconductor surface
We present the results of local tunneling conductivity spatial distribution
detailed theoretical investigations in vicinity of impurity atom for a wide
range of applied bias voltage. We observed Fano resonance in tunneling
conductivity resulting from interference between resonant tunneling channel
through impurity energy level and direct tunneling channel between the
tunneling contact leads. We have found that interference between tunneling
channels strongly modifies form of tunneling conductivity measured by the
scanning tunneling microscopy/spectroscopy (STM/STS) depending on the distance
value from the impurity.Comment: 4 pages, 3 figure
Reaction of Boron Chloride with Methoxyamine Hydrochloride
Boron chloride and methoxyamine hydrochloride were reacted in refluxing chlorobenzene. The reaction product was then identified as possibly being N-trimethoxy-B-trichloroborazine. The identification was made by comparing the Infra-re spectrum of the reaction product with the spectra of N-trimethyl-B-trichloroborzaine, methoxyamine hydrocholoride and, the addition compond MeNH2-BC13
Dielectric Function of Diluted Magnetic Semiconductors in the Infrared Regime
We present a study of the dielectric function of metallic (III,Mn)V diluted
magnetic semiconductors in the infrared regime. Our theoretical approach is
based on the kinetic exchange model for carrier induced (III,Mn)V
ferromagnetism. The dielectric function is calculated within the random phase
approximation and, within this metallic regime, we treat disorder effects
perturbatively and thermal effects within the mean field approximation. We also
discuss the implications of this calculations on carrier concentration
measurements from the optical f-sum rule and the analysis of plasmon-phonon
coupled modes in Raman spectra.Comment: 6 pages, 6 figures include
Program on stimulating operational private sector use of Earth observation satellite information
Ideas for new businesses specializing in using remote sensing and computerized spatial data systems were developd. Each such business serves as an 'information middleman', buying raw satellite or aircraft imagery, processing these data, combining them in a computer system with customer-specific information, and marketing the resulting information products. Examples of the businesses the project designed are: (1) an agricultural facility site evaluation firm; (2) a mass media grocery price and supply analyst and forecaster; (3) a management service for privately held woodlots; (4) a brokerage for insulation and roofing contractors, based on infrared imagery; (5) an expanded real estate information service. In addition, more than twenty-five other commercially attractive ideas in agribusiness, forestry, mining, real estate, urban planning and redevelopment, and consumer information were created. The commercial feasibility of the five business was assessed. This assessment included market surveys, revenue projections, cost analyses, and profitability studies. The results show that there are large and enthusiastic markets willing to pay for the services these businesses offer, and that the businesses could operate profitably
Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism
Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response. The present study aimed at the correlation of the G308A TNF-alpha polymorphism with the response to antiviral combination therapy in chronic hepatitis C. Patients and Methods: 62 patients with HCV and 119 healthy unrelated controls were genotyped for the G308A TNF-alpha promoter polymorphism. The patients received 3 x 3 million units of interferon alfa-2a and 1,0001,200 mg ribavirin daily according to their body weight. A response was defined as absence of HCV-RNA and normalization of S-ALT after 6 months of combination therapy. Results:With respect to the allele and genotype frequency, a significant difference was not observed between controls and patients with chronic hepatitis C. Furthermore, such a difference was also not observed if responders and non-responders to antiviral therapy were compared. Conclusions: The promoter polymorphism of the TNF-alpha gene investigated herein is equally distributed in healthy individuals and patients with hepatitis C and does not seem to predict the response to therapy with interferon alfa-2a and ribavirin. Copyright (C) 2003 S. Karger AG, Basel
Estimating novel potential drug targets of Plasmodium falciparum by analysing the metabolic network of knock-out strains in silico
Malaria is one of the worldâs most common and serious diseases causing death of about 3 million people
each year. Its most severe occurrence is caused by the protozoan Plasmodium falciparum. Biomedical
research could enable treating the disease by effectively and specifically targeting essential enzymes of
this parasite. However, the parasite has developed resistance to existing drugsmaking it indispensable to
discover new drugs. We have established a simple computational tool which analyses the topology of the
metabolic network of P. falciparum to identify essential enzymes as possible drug targets.Weinvestigated
the essentiality of a reaction in the metabolic network by deleting (knocking-out) such a reaction in silico.
The algorithmselected neighbouring compounds of the investigated reaction that had to be produced by
alternative biochemical pathways. Using breadth first searches, we tested qualitatively if these products
could be generated by reactions that serve as potential deviations of the metabolic flux. With this we
identified 70 essential reactions. Our results were compared with a comprehensive list of 38 targets of
approved malaria drugs. When combining our approach with an in silico analysis performed recently
[Yeh, I., Hanekamp, T., Tsoka, S., Karp, P.D., Altman, R.B., 2004. Computational analysis of Plasmodium
falciparum metabolism: organizing genomic information to facilitate drug discovery. Genome Res. 14,
917â924] we could improve the precision of the prediction results. Finally we present a refined list of 22
new potential candidate targets for P. falciparum, half of which have reasonable evidence to be valid
targets against micro-organisms and cancer
Conductance plateau in quantum spin transport through an interacting quantum dot
Quantum spin transport is studied in an interacting quantum dot. It is found
that a conductance "plateau" emerges in the non-linear charge conductance by a
spin bias in the Kondo regime. The conductance plateau, as a complementary to
the Kondo peak, originates from the strong electron correlation and exchange
processes in the quantum dot, and can be regarded as one of the characteristics
in quantum spin transport.Comment: 5 pages, 5 figure
The role of Cahn and Sivers effects in Deep Inelastic Scattering
The role of intrinsic \bfk_\perp in inclusive and semi-inclusive Deep
Inelastic Scattering processes () is studied with exact
kinematics within QCD parton model at leading order; the dependence of the
unpolarized cross section on the azimuthal angle between the leptonic and the
hadron production planes (Cahn effect) is compared with data and used to
estimate the average values of both in quark distribution and
fragmentation functions. The resulting picture is applied to the description of
the weighted single spin asymmetry recently
measured by the HERMES collaboration at DESY; this allows to extract some
simple models for the quark Sivers functions. These are compared with the
Sivers functions which succeed in describing the data on transverse single spin
asymmetries in \pup p \to \pi X processes; the two sets of functions are not
inconsistent. The extracted Sivers functions give predictions for the COMPASS
measurement of in agreement with recent
preliminary data, while their contribution to HERMES is
computed and found to be small. Predictions for for kaon production at HERMES are also given.Comment: 21 pages, 12 figures, revtex, version published in PRD, one figure,
comments and references adde
Evaluation of aircraft microwave data for locating zones for well stimulation and enhanced gas recovery
Imaging radar was evaluated as an adjunct to conventional petroleum exploration techniques, especially linear mapping. Linear features were mapped from several remote sensor data sources including stereo photography, enhanced LANDSAT imagery, SLAR radar imagery, enhanced SAR radar imagery, and SAR radar/LANDSAT combinations. Linear feature maps were compared with surface joint data, subsurface and geophysical data, and gas production in the Arkansas part of the Arkoma basin. The best LANDSAT enhanced product for linear detection was found to be a winter scene, band 7, uniform distribution stretch. Of the individual SAR data products, the VH (cross polarized) SAR radar mosaic provides for detection of most linears; however, none of the SAR enhancements is significantly better than the others. Radar/LANDSAT merges may provide better linear detection than a single sensor mapping mode, but because of operator variability, the results are inconclusive. Radar/LANDSAT combinations appear promising as an optimum linear mapping technique, if the advantages and disadvantages of each remote sensor are considered
Program on stimulating operational private sector use of Earth observation satellite data
There are no author-identified significant results in this report
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