Extrapulmonary Tuberculosis: A retrospective Study at a tertiary care hospital in Palpa, Nepal

Background: Extra-pulmonary tuberculosis (EPTB) is a significant global health problem. Related studies to it in different places and diff erent durations are indicated by many previous research findings. Findings of this study could be beneficial for its preventive and control strategies. Methodology: Retrospective analysis of clinical specimens submitted to Central laboratory of Lumbini Medical College and Teaching Hospital (LMCTH) for extrapulmonary tuberculosis was performed. Total 261 samples submitted from April 2011 to February 2013 were included for analysis in this study. Results: Total 20.7% (54/261) prevalence of EPTB was reported. Based on sites involved; lymph node 87.03%, pleural effusion7.40%, peritoneal5.55% were found. Genderwise equal prevalence was seen among male and females. Age-wise prevalence among patients between 21-40 years was reported. Conclusion: Our finding indicates great necessity for further large scale study on prevalence of EPTB in this location for its prevention and control

Assessment of Yield and Yield Attributing Characters of Hybrid Maize using Nutrient Expert® Maize Model in Eastern Terai of Nepal

Indiscriminate use of fertilizer and lack of site specific nutrient management technology is the main cause of low maize productivity in Nepal. Thus, field experiments on farmer\u27s field were conducted on maize to assess the productivity at two sites of Jhapa district viz. Damak and Gauradaha using Nutrient Expert® Maize model from November 2015 to May 2016. The experiment was laid out in Randomized Completely Block Design consisting two treatments viz. NE (Nutrient Expert recommendation) and FFP (Farmer\u27s Fertilizer Practice) with twenty replications. The result revealed significant differences in terms of grain yield, stover yield, biological yield, and yield attributing characters. NE based practices produced higher grain yield (9.22 t ha-1), which was 86.6 percent higher than FFP (4.94 t ha-1). Similarly, higher average cob number m 2 (8.2), average kernel rows cob-1 (14.2), average kernels number row-1 (589.9) and test weight (361.4 g) were recorded in NE based practice. Thus, NE based practice can be adopted for obtaining higher productivity in eastern terai region of Nepal

Perturbation of FRW Spacetime in NP Formalism

Perturbation of FRW spacetime is carried out in NP formalism. The equation governing the scalar, vector and tensor modes take on a very simple and transparent form. All of them can be combined in one master equation for all helicities. The solutions for the closed, flat and open FRW are analytic continuation of the same functions, so only the solutions in the closed model are described. The scalar equation is the same as that of the conformally coupled massless Klein-Gordon field, the vectorial ones are the same as Maxwell equations, and the tensorial ones are for spin-2 fields. The corresponding eigen-functions are all determined, and in particular, the Green's function and the Lienard-Wiechert type potential also solved. These solutions reduce to the familiar form in flat space.Comment: 11 pages including 3 figure

Quasi-normal modes of Schwarzschild-de Sitter black holes

The low-laying frequencies of characteristic quasi-normal modes (QNM) of Schwarzschild-de Sitter (SdS) black holes have been calculated for fields of different spin using the 6th-order WKB approximation and the approximation by the P\"{o}shl-Teller potential. The well-known asymptotic formula for large $l$ is generalized here on a case of the Schwarzchild-de Sitter black hole. In the limit of the near extreme $\Lambda$ term the results given by both methods are in a very good agreement, and in this limit fields of different spin decay with the same rate.Comment: 9 pages, 1 ancillary Mathematica(R) noteboo

Effects of climatic factors on diarrheal diseases among children below 5 years of age at national and subnational levels in Nepal: an ecological study

INTRODUCTION: The incidence of diarrhea, a leading cause of morbidity and mortality in low-income countries such as Nepal, is temperature-sensitive, suggesting it could be associated with climate change. With climate change fueled increases in the mean and variability of temperature and precipitation, the incidence of water and food-borne diseases are increasing, particularly in sub-Saharan Africa and South Asia. This national-level ecological study was undertaken to provide evidence linking weather and climate with diarrhea incidence in Nepal. METHOD: We analyzed monthly diarrheal disease count and meteorological data from all districts, spanning 15 eco-development regions of Nepal. Meteorological data and monthly data on diarrheal disease were sourced, respectively, from the Department of Hydrology and Meteorology and Health Management Information System (HMIS) of the Government of Nepal for the period from 2002 to 2014. Time-series log-linear regression models assessed the relationship between maximum temperature, minimum temperature, rainfall, relative humidity, and diarrhea burden. Predictors with p-values < 0.25 were retained in the fitted models. RESULTS: Overall, diarrheal disease incidence in Nepal significantly increased with 1 degrees C increase in mean temperature (4.4%; 95% CI: 3.95, 4.85) and 1 cm increase in rainfall (0.28%; 95% CI: 0.15, 0.41). Seasonal variation of diarrheal incidence was prominent at the national level (11.63% rise in diarrheal cases in summer (95% CI: 4.17, 19.61) and 14.5% decrease in spring (95% CI: -18.81, -10.02) compared to winter season). Moreover, the effects of temperature and rainfall were highest in the mountain region compared to other ecological regions of Nepal. CONCLUSION: Our study provides empirical evidence linking weather factors and diarrheal disease burden in Nepal. This evidence suggests that additional climate change could increase diarrheal disease incidence across the nation. Mountainous regions are more sensitive to climate variability and consequently the burden of diarrheal diseases. These findings can be utilized to allocate necessary resources and envision a weather-based early warning system for the prevention and control of diarrheal diseases in Nepal