105 research outputs found
From Industrialization to Extraction:Visions and Practices of Development in Soviet Central Asia: Introduction to the Forum
Anticipation and visual search behaviour in expert soccer goalkeepers
A novel methodological approach is presented to examine the visual search behaviours employed by expert goalkeepers during simulated penalty kick situations in soccer. Expert soccer goalkeepers were classified as successful or unsuccessful based on their performance on a film-based test of anticipation skill, thereby allowing an intra-group comparison of visual search behaviour on the task. The anticipation test required participants to move a joystick in response to penalty kick situations presented on a large screen. The proportion of penalties saved was assessed as well as the frequency and time of initiation of joystick corrections. Visual search behaviour was examined using a portable eye movement registration system. The successful experts were more accurate in predicting the height and direction of the penalty kick, waited longer before initiating a response and appeared to spend longer periods of time fixating on the non-kicking leg compared with the nonsuccessful experts. © 2005 Taylor & Francis
Visual search, anticipation and expertise in soccer goalkeepers
Comparaison, lors d'une tâche expérimentale, des stratégies de recherche visuelles de gardiens de but novices et experts et de leur performance d'anticipation (paradigme de perception-action) lors de penaltie
Ices in planet-forming disks: self-consistent ice opacities in disk models
Stars and planetary system
Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus
0.001). CONCLUSIONS: In T2DM patients, pioglitazone was associated with improvement in some measures of left ventricular diastolic function, myocardial glucose uptake, and whole-body insulin sensitivity. The functional changes, however, were not associated with myocardial substrate and high-energy phosphate metabolis
Pre-cachexia in patients with stages I-III non-small cell lung cancer: Systemic inflammation and functional impairment without activation of skeletal muscle ubiquitin proteasome system.
AbstractCachexia is a prevalent phenomenon of non-small cell lung cancer (NSCLC) which is responsible for increased mortality and deterioration of physical performance. Preclinical research indicates that systemic inflammation induces cachexia-related muscle wasting through muscular Nuclear Factor-kappa B (NF-κB) signaling and subsequent ubiquitin proteasome system (UPS)-mediated proteolysis. As these pathways could be a target for early intervention strategies, it needs to be elucidated whether increased activation of these pathways is already present in early stage NSCLC cachexia. The aim of the present study was therefore to assess muscular NF-κB and UPS activation in patients with NSCLC pre-cachexia.Sixteen patients with newly diagnosed stages I–III NSCLC having <10% weight loss and ten healthy controls were studied. Body composition, systemic inflammation and exercise capacity were assessed in all subjects and NF-κB and UPS activity in vastus lateralis muscle biopsies in a subset.Patients showed increased plasma levels of C-reactive protein (CRP) (P<0.001), soluble Tumor Necrosis Factor receptor 1 (sTNF-R1) (P<0.05), fibrinogen (P<0.001) and decreased levels of albumin (P<0.001). No changes in fat free body mass or skeletal muscle NF-κB and UPS activity were observed, while peak oxygen consumption (V˙O2 peak) was significantly decreased in patients compared with healthy controls.In conclusion, this exploratory study demonstrates significantly reduced exercise capacity in NSCLC pre-cachexia despite maintenance of muscle mass and unaltered indices of UPS activation. The absence of muscular NF-κB-dependent inflammatory signaling supports the notion that transition of systemic to local inflammation is required to initiate UPS-dependent muscle wasting characteristic for (experimental) cachexia
Desempenho de Lecanicillium lecanii em meios de cultura contendo vitaminas e concentrações de extrato de levedura
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