77 research outputs found

    Quasimonoenergetic electron acceleration in the self-modulated laser wakefield regime

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    Details on the generation of (multiple) quasimonoenergetic electron bunches in the self-modulated laser wakefield acceleration (SMLWFA) regime are presented. This type of laser-plasma interaction can result in pronounced longitudinal laser pulse fragmentation, dependent on plasma density and laser intensity. It is shown by experiments and particle-in-cell simulations that these laser pulse fragments can be powerful enough to trigger nonlinear plasma wave breaking, injection, and acceleration of electrons to quasimonoenergetic energies. With high plasma densities, self-modulation is promoted, and the advantages of SMLWFA such as especially high accelerating fields and short electron bunches (<5 fs) can be harvested. In addition, more than one quasimonoenergetic electron bunch can be created, with a temporal spacing between each bunch of only few tens of femtoseconds, again governed by plasma density

    Study of photo-proton reactions driven by bremsstrahlung radiation of high-intensity laser generated electrons

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    Photo-nuclear reactions were investigated using a high power table-top laser. The laser system at the University of Jena ( I similar to 3-5 x 10(19) W cm(-2)) produced hard bremsstrahlung photons ( kT similar to 2(9 MeV) via a laser-gas interaction which served to induce ( gamma, p) and ( gamma, n) reactions in Mg, Ti, Zn and Mo isotopes. Several ( gamma, p) decay channels were identified using nuclear activation analysis to determine their integral reaction yields

    Serum levels of cytokines and C-reactive protein in acute ischemic stroke patients, and their relationship to stroke lateralization, type, and infarct volume

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    There is increasing evidence that inflammation plays an important role in the progression of acute ischemic stroke (AIS). The primary aims of this study were to examine the serum levels of 13 cytokines, C-reactive protein (CRP), glucose, and hemoglobin in AIS patients, and their relationship to stroke lateralization, type, and infarct volume. Forty-five patients with AIS were evaluated. Blood samples were taken within 72 h, and volumetric analyses performed within 1–7 days after AIS onset. Cytokines were measured in serum from all patients and from 40 control subjects using Luminex Bio-Plex XMap technology. The levels of interleukin (IL)-1ra (p < 0.001), IL-6 (p < 0.001), IL-8 (p < 0.001), IL-9 (p = 0.038), IL-10 (p = 0.001), IL-12 (p = 0.001), IL-18 (p < 0.001), and GRO-α (CXCL1) (p = 0.017) were significantly higher in the AIS patients than in the controls. The IL-8 level was significantly correlated with age in the patient group (r = 0.52, p < 0.001). None of the variables were found to be associated with stroke lateralization. Infarct volume was significantly positively correlated with CRP level (r = 0.47, p = 0.005). Patients with radiologically confirmed infarctions had significantly elevated serum levels of GRO-α (p = 0.023). The cytokine profile of the AIS patients supports not only earlier findings of a proinflammatory response but also early activation of endogenous immunosuppressive mechanisms. Novel findings of this study are elevated serum levels of IL-9 and GRO-α. Elevated GRO-α in AIS patients with radiologically confirmed infarctions suggests that GRO-α is specific for stroke of known etiology. Our results indicate that CRP plays an important role in the progression of cerebral tissue injury

    Nuclear astrophysics: the unfinished quest for the origin of the elements

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    Half a century has passed since the foundation of nuclear astrophysics. Since then, this discipline has reached its maturity. Today, nuclear astrophysics constitutes a multidisciplinary crucible of knowledge that combines the achievements in theoretical astrophysics, observational astronomy, cosmochemistry and nuclear physics. New tools and developments have revolutionized our understanding of the origin of the elements: supercomputers have provided astrophysicists with the required computational capabilities to study the evolution of stars in a multidimensional framework; the emergence of high-energy astrophysics with space-borne observatories has opened new windows to observe the Universe, from a novel panchromatic perspective; cosmochemists have isolated tiny pieces of stardust embedded in primitive meteorites, giving clues on the processes operating in stars as well as on the way matter condenses to form solids; and nuclear physicists have measured reactions near stellar energies, through the combined efforts using stable and radioactive ion beam facilities. This review provides comprehensive insight into the nuclear history of the Universe and related topics: starting from the Big Bang, when the ashes from the primordial explosion were transformed to hydrogen, helium, and few trace elements, to the rich variety of nucleosynthesis mechanisms and sites in the Universe. Particular attention is paid to the hydrostatic processes governing the evolution of low-mass stars, red giants and asymptotic giant-branch stars, as well as to the explosive nucleosynthesis occurring in core-collapse and thermonuclear supernovae, gamma-ray bursts, classical novae, X-ray bursts, superbursts, and stellar mergers.Comment: Invited Review. Accepted for publication in "Reports on Progress in Physics" (version with low-resolution figures

    Simulated changes in vegetation distribution, land carbon storage, and atmospheric CO2 in response to a collapse of the North Atlantic thermohaline circulation

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    Measurements on glacial ice show that atmospheric CO2 varied by 20ppmv with large iceberg discharges into the North Atlantic (NA) and themost prominent Dansgaard/ Oeschger (D/O) climate fluctuations. CO2variations during less pronounced D/O events were smaller than a fewppm. The D/O fluctuations have been linked to changes in the NAThermohaline Circulation (THC). Here, we analyse how abrupt changes inthe NA THC affect the terrestrial carbon cycle by forcing theLund-Potsdam-Jena Dynamic Global Vegetation Model with climateperturbations from freshwater experiments with the ECBILT-CLIOgeneral circulation model. Changes in the marine carbon cycle are notaddressed. Modelled NA THC collapsed and recovered after about amillennium in response to prescribed freshwater forcing. The initialcooling of several Kelvin over Eurasia causes a reduction ofextant boreal and temperate forests and a decrease in carbon storage inhigh northern latitudes, whereas improved growing conditions andslower soil decomposition rates lead to enhanced storage inmid-latitudes. The magnitude and evolution of global terrestrialcarbon storage in response to abrupt THC changes depends sensitivelyon the initial climate conditions. Terrestrial storage varies between-67 and +50 PgC for arange of experiments that start at different times during the last21,000 years. Simulated peak-to-peak differences in atmospheric CO2and d13C are between {6 and 18 ppmv} and 0.180.18 and 0.300.30~\mypermil and compatible with the ice core CO2 record

    Generation of quasimonoenergetic electron bunches with 80-fs laser pulses

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    Highly collimated, quasimonoenergetic multi-MeV electron bunches were generated by the interaction of tightly focused, 80-fs laser pulses in a high-pressure gas jet. These monoenergetic bunches are characteristic of wakefield acceleration in the highly nonlinear wave breaking regime, which was previously thought to be accessible only by much shorter laser pulses in thinner plasmas. In our experiment, the initially long laser pulse was modified in underdense plasma to match the necessary conditions. This picture is confirmed by semianalytical scaling laws and 3D particle-in-cell simulations. Our results show that laser-plasma interaction can drive itself towards this type of laser wakefield acceleration even if the initial laser and plasma parameters are outside the required regime

    Direct evidence of strongly inhomogeneous energy deposition in target heating with laser-produced ion beams

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    We report on strong nonuniformities in target heating with intense, laser-produced proton beams. The observed inhomogeneity in energy deposition can strongly perturb equation of state EOS measurements with laser-accelerated ions which are planned in several laboratories. Interferometric measurements of the target expansion show different expansion velocities on the front and rear surfaces, indicating a strong difference in local temperature. The nonuniformity indicates at an additional heating mechanism, which seems to originate from electrons in the keV range
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