127 research outputs found
Generalised-Lorentzian Thermodynamics
We extend the recently developed non-gaussian thermodynamic formalism
\cite{tre98} of a (presumably strongly turbulent) non-Markovian medium to its
most general form that allows for the formulation of a consistent thermodynamic
theory. All thermodynamic functions, including the definition of the
temperature, are shown to be meaningful. The thermodynamic potential from which
all relevant physical information in equilibrium can be extracted, is defined
consistently. The most important findings are the following two: (1) The
temperature is defined exactly in the same way as in classical statistical
mechanics as the derivative of the energy with respect to the entropy at
constant volume. (2) Observables are defined in the same way as in Boltzmannian
statistics as the linear averages of the new equilibrium distribution function.
This lets us conclude that the new state is a real thermodynamic equilibrium in
systems capable of strong turbulence with the new distribution function
replacing the Boltzmann distribution in such systems. We discuss the ideal gas,
find the equation of state, and derive the specific heat and adiabatic exponent
for such a gas. We also derive the new Gibbsian distribution of states. Finally
we discuss the physical reasons for the development of such states and the
observable properties of the new distribution function.Comment: 13 pages, 1 figur
Collisional damping rates for plasma waves
The distinction between the plasma dynamics dominated by collisional
transport versus collective processes has never been rigorously addressed until
recently. A recent paper [Yoon et al., Phys. Rev. E 93, 033203 (2016)]
formulates for the first time, a unified kinetic theory in which collective
processes and collisional dynamics are systematically incorporated from first
principles. One of the outcomes of such a formalism is the rigorous derivation
of collisional damping rates for Langmuir and ion-acoustic waves, which can be
contrasted to the heuristic customary approach. However, the results are given
only in formal mathematical expressions. The present Brief Communication
numerically evaluates the rigorous collisional damping rates by considering the
case of plasma particles with Maxwellian velocity distribution function so as
to assess the consequence of the rigorous formalism in a quantitative manner.
Comparison with the heuristic ("Spitzer") formula shows that the accurate
damping rates are much lower in magnitude than the conventional expression,
which implies that the traditional approach over-estimates the importance of
attenuation of plasma waves by collisional relaxation process. Such a finding
may have a wide applicability ranging from laboratory to space and
astrophysical plasmas.Comment: 5 pages, 2 figures; Published in Physics of Plasmas, volume/Issue
23/6. Publisher: AIP Publishing LLC. Date: Jun 1, 2016. URL:
http://aip.scitation.org/doi/10.1063/1.4953802 Rights managed by AIP
Publishing LL
Plasmoid-Induced-Reconnection and Fractal Reconnection
As a key to undertanding the basic mechanism for fast reconnection in solar
flares, plasmoid-induced-reconnection and fractal reconnection are proposed and
examined. We first briefly summarize recent solar observations that give us
hints on the role of plasmoid (flux rope) ejections in flare energy release. We
then discuss the plasmoid-induced-reconnection model, which is an extention of
the classical two-ribbon-flare model which we refer to as the CSHKP model. An
essential ingredient of the new model is the formation and ejection of a
plasmoid which play an essential role in the storage of magnetic energy (by
inhibiting reconnection) and the induction of a strong inflow into reconnection
region. Using a simple analytical model, we show that the plasmoid ejection and
acceleration are closely coupled with the reconnection process, leading to a
nonlinear instability for the whole dynamics that determines the macroscopic
reconnection rate uniquely. Next we show that the current sheet tends to have a
fractal structure via the following process path: tearing, sheet thinning,
Sweet- Parker sheet, secondary tearing, further sheet thinning... These
processes occur repeatedly at smaller scales until a microscopic plasma scale
(either the ion Larmor radius or the ion inertial length) is reached where
anomalous resistivity or collisionless reconnection can occur. The current
sheet eventually has a fractal structure with many plasmoids (magnetic islands)
of different sizes. When these plasmoids are ejected out of the current sheets,
fast reconnection occurs at various different scales in a highly time dependent
manner. Finally, a scenario is presented for fast reconnection in the solar
corona on the basis of above plasmoid-induced-reconnection in a fractal current
sheet.Comment: 9 pages, 11 figures, with using eps.sty; Earth, Planets and Space in
press; ps-file is also available at
http://stesun8.stelab.nagoya-u.ac.jp/~tanuma/study/shibata2001
Prognostic value of different CT measurements in early therapy response evaluation in patients with metastatic colorectal cancer
OBJECTIVES: Patients with advanced stage colorectal carcinoma (CRC) display hepatic metastases on initial staging in up to 20% of cases. The effectiveness of chemotherapy is generally evaluated by computed tomography (CT) imaging using standardized criteria (RECIST). However, RECIST is not always optimal, and other criteria have been shown to correlate with pathologic response and overall survival. The aim of this study was to evaluate the prognostic value of different CT measurement for response assessment after initiation of chemotherapy in patients with synchronous colorectal cancer liver metastases.
METHODS: Fifty-five patients with CRC and synchronous hepatic metastases were evaluated retrospectively at 2 academic centers. Different size, volume, ratio and attenuation parameters were determined at baseline and after 3 cycles of chemotherapy. The prognostic value of baseline measurements and of the change between baseline and second measurements was analyzed using Kaplan-Meier estimates.
RESULTS: Median time to progression was 279 days, median overall survival was 704 days. In this selective patient population, neither a significant prognostic value of initial baseline CT parameters nor a prognostic value of the change between the first and the second CT measurements was found.
CONCLUSION: Initial morphological response assessment using different CT measurements has no prognostic value concerning time to progression or overall survival in patients with synchronous colorectal liver metastases
The First Magnetic Fields
We review current ideas on the origin of galactic and extragalactic magnetic
fields. We begin by summarizing observations of magnetic fields at cosmological
redshifts and on cosmological scales. These observations translate into
constraints on the strength and scale magnetic fields must have during the
early stages of galaxy formation in order to seed the galactic dynamo. We
examine mechanisms for the generation of magnetic fields that operate prior
during inflation and during subsequent phase transitions such as electroweak
symmetry breaking and the quark-hadron phase transition. The implications of
strong primordial magnetic fields for the reionization epoch as well as the
first generation of stars is discussed in detail. The exotic, early-Universe
mechanisms are contrasted with astrophysical processes that generate fields
after recombination. For example, a Biermann-type battery can operate in a
proto-galaxy during the early stages of structure formation. Moreover, magnetic
fields in either an early generation of stars or active galactic nuclei can be
dispersed into the intergalactic medium.Comment: Accepted for publication in Space Science Reviews. Pdf can be also
downloaded from http://canopus.cnu.ac.kr/ryu/cosmic-mag1.pd
Corrigendum: Physiological and Proteomic Analysis of the Rice Mutant cpm2 Suggests a Negative Regulatory Role of Jasmonic Acid in Drought Tolerance
Physiological and Proteomic Analysis of the Rice Mutant cpm2 Suggests a Negative Regulatory Role of Jasmonic Acid in Drought Tolerance
It is widely known that numerous adaptive responses of drought-stressed plants are stimulated by chemical messengers known as phytohormones. Jasmonic acid (JA) is one such phytohormone. But there are very few reports revealing its direct implication in drought related responses or its cross-talk with other phytohormones. In this study, we compared the morpho-physiological traits and the root proteome of a wild type (WT) rice plant with its JA biosynthesis mutant coleoptile photomorphogenesis 2 (cpm2), disrupted in the allene oxide cyclase (AOC) gene, for insights into the role of JA under drought. The mutant had higher stomatal conductance, higher water use efficiency and higher shoot ABA levels under severe drought as compared to the WT. Notably, roots of cpm2 were better developed compared to the WT under both, control and drought stress conditions. Root proteome was analyzed using the Tandem Mass Tag strategy to better understand this difference at the molecular level. Expectedly, AOC was unique but notably highly abundant under drought in the WT. Identification of other differentially abundant proteins (DAPs) suggested increased energy metabolism (i.e., increased mobilization of resources) and reactive oxygen species scavenging in cpm2 under drought. Additionally, various proteins involved in secondary metabolism, cell growth and cell wall synthesis were also more abundant in cpm2 roots. Proteome-guided transcript, metabolite, and histological analyses provided further insights into the favorable adaptations and responses, most likely orchestrated by the lack of JA, in the cpm2 roots. Our results in cpm2 are discussed in the light of JA crosstalk to other phytohormones. These results together pave the path for understanding the precise role of JA during drought stress in rice
Solar and heliospheric sources of suprathermal and energetic particle populations
Objectives and some preliminary findings of an ongoing international team project carried out at ISSI, Bern will be presented. Suprathermal and energetic particle
s in interplanetary space have a multitude of origins,
i.e. acceleration and propagation hi stories. Solar flares, coronal mass ejections (CMEs), co-rotating interaction regions (CIRs), the heliospheric termination shock, planetary bow shocks and magnetospheres have all been recognized as energetic particle sources. Less energetic (suprathermal) particles of solar origin and pick-up ions have also a vital role both in their own right and as seeds of energetic particles accelerated in interplanetary disturbances. The relative contributions of various particle populations vary with energy and with the phase of the solar cycle. Particular attention will be given in our project to quiet periods and to large events. While quiet-time fluxes are expected to shed light on some
base-line features of coronal and interplanetary acceleration processes, relatively large events dominate bot
h the long-term fluence levels and the statistical properties of cumulative fluence plots. The importance of energetic and suprathermal particles that mostly cannot escape into interplanetary space, but contribute to co
ronal heating and possibly also to solar wind composition, will also be discussed.
B. Sripathi Acharya, Sunil Gupta, P. Jagadeesan, Atul Jain, S. Karthikeyan, Samuel Morris, and Suresh Tonwa
The Glycosylphosphatidylinositol-PLC in Trypanosoma brucei Forms a Linear Array on the Exterior of the Flagellar Membrane Before and After Activation
Bloodstream forms of Trypanosoma brucei contain a glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC) that cleaves the GPI-anchor of the variable surface glycoprotein (VSG). Its location in trypanosomes has been controversial. Here, using confocal microscopy and surface labelling techniques, we show that the GPI-PLC is located exclusively in a linear array on the outside of the flagellar membrane, close to the flagellar attachment zone, but does not co-localize with the flagellar attachment zone protein, FAZ1. Consequently, the GPI-PLC and the VSG occupy the same plasma membrane leaflet, which resolves the topological problem associated with the cleavage reaction if the VSG and the GPI-PLC were on opposite sides of the membrane. The exterior location requires the enzyme to be tightly regulated to prevent VSG release under basal conditions. During stimulated VSG release in intact cells, the GPI-PLC did not change location, suggesting that the release mechanism involves lateral diffusion of the VSG in the plane of the membrane to the fixed position of the GPI-PLC
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