7,437 research outputs found
A specification-based IDS for detecting attacks on RPL-based network topology
Routing Protocol for Low power and Lossy network (RPL) topology attacks can downgrade the network performance significantly by disrupting the optimal protocol structure. To detect such threats, we propose a RPL-specification, obtained by a semi-auto profiling technique that constructs a high-level abstract of operations through network simulation traces, to use as reference for verifying the node behaviors. This specification, including all the legitimate protocol states and transitions with corresponding statistics, will be implemented as a set of rules in the intrusion detection agents, in the form of the cluster heads propagated to monitor the whole network. In order to save resources, we set the cluster members to report related information about itself and other neighbors to the cluster head instead of making the head overhearing all the communication. As a result, information about a cluster member will be reported by different neighbors, which allow the cluster head to do cross-check. We propose to record the sequence in RPL Information Object (DIO) and Information Solicitation (DIS) messages to eliminate the synchronized issue created by the delay in transmitting the report, in which the cluster head only does cross-check on information that come from sources with the same sequence. Simulation results show that the proposed Intrusion Detection System (IDS) has a high accuracy rate in detecting RPL topology attacks, while only creating insignificant overhead (about 6.3%) that enable its scalability in large-scale network
Kinetic Monte Carlo Simulations of Crystal Growth in Ferroelectric Alloys
The growth rates and chemical ordering of ferroelectric alloys are studied
with kinetic Monte Carlo (KMC) simulations using an electrostatic model with
long-range Coulomb interactions, as a function of temperature, chemical
composition, and substrate orientation. Crystal growth is characterized by
thermodynamic processes involving adsorption and evaporation, with
solid-on-solid restrictions and excluding diffusion. A KMC algorithm is
formulated to simulate this model efficiently in the presence of long-range
interactions. Simulations were carried out on Ba(Mg_{1/3}Nb_{2/3})O_3 (BMN)
type materials. Compared to the simple rocksalt ordered structures, ordered BMN
grows only at very low temperatures and only under finely tuned conditions. For
materials with tetravalent compositions, such as (1-x)Ba(Mg_{1/3}Nb_{2/3})O_3 +
xBaZrO_3 (BMN-BZ), the model does not incorporate tetravalent ions at
low-temperature, exhibiting a phase-separated ground state instead. At higher
temperatures, tetravalent ions can be incorporated, but the resulting crystals
show no chemical ordering in the absence of diffusive mechanisms.Comment: 13 pages, 16 postscript figures, submitted to Physics Review B
Journa
The activation energy for GaAs/AlGaAs interdiffusion
Copyright 1997 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Journal of Applied Physics 82, 4842 (1997) and may be found at
Elucidating the Surface Functionality of Biomimetic RGD Peptides Immobilized on Nano-P(3HB-co-4HB) for H9c2 Myoblast Cell Proliferation
Biomaterial scaffolds play crucial role to promote cell proliferation and foster the regeneration of new tissues. The progress in material science has paved the way for the generation of ingenious biomaterials. However, these biomaterials require further optimization to be effectively used in existing clinical treatments. It is crucial to develop biomaterials which mimics structure that can be actively involved in delivering signals to cells for the formation of the regenerated tissue. In this research we nanoengineered a functional scaffold to support the proliferation of myoblast cells. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] copolymer is chosen as scaffold material owing to its desirable mechanical and physical properties combined with good biocompatibility, thus eliciting appropriate host tissue responses. In this study P(3HB-co-4HB) copolymer was biosynthesized using Cupriavidus malaysiensis USMAA1020 transformant harboring additional PHA synthase gene, and the viability of a novel P(3HB-co-4HB) electrospun nanofiber scaffold, surface functionalized with RGD peptides, was explored. In order to immobilize RGD peptides molecules onto the P(3HB-co-4HB) nanofibers surface, an aminolysis reaction was performed. The nanoengineered scaffolds were characterized using SEM, organic elemental analysis (CHN analysis), FTIR, surface wettability and their in vitro degradation behavior was evaluated. The cell culture study using H9c2 myoblast cells was conducted to assess the in vitro cellular response of the engineered scaffold. Our results demonstrated that nano-P(3HB-co-4HB)-RGD scaffold possessed an average fiber diameter distribution between 200 and 300 nm, closely biomimicking, from a morphological point of view, the structural ECM components, thus acting as potential ECM analogs. This study indicates that the surface conjugation of biomimetic RGD peptide to the nano-P(3HB-co-4HB) fibers increased the surface wettability (15 ± 2°) and enhanced H9c2 myoblast cells attachment and proliferation. In summary, the study reveals that nano-P(3HB-co-4HB)-RGD scaffold can be considered a promising candidate to be further explored as cardiac construct for building cardiac construct
s-ordered phase-sum and phase-difference distribuitons of entangled coherent states
The -ordered phase-sum and phase-difference distributions are considered
for Bell-like superpositions of two-mode coherent states. The distributions are
sensitive, respectively, to the sum and difference of the phases of the
entangled coherent states. They show loss of information about the entangled
state and may take on negative values for some orderings .Comment: 8 pages, 2 figures, iopart. accepted for publication in J. Opt. B:
Quantum Semiclass Op
Charge transfer electrostatic model of compositional order in perovskite alloys
We introduce an electrostatic model including charge transfer, which is shown
to account for the observed B-site ordering in Pb-based perovskite alloys. The
model allows charge transfer between A-sites and is a generalization of
Bellaiche and Vanderbilt's purely electrostatic model. The large covalency of
Pb^{2+} compared to Ba^{2+} is modeled by an environment dependent effective
A-site charge. Monte Carlo simulations of this model successfully reproduce the
long range compositional order of both Pb-based and Ba-based complex
A(BB^{'}B^{''})O_3 perovskite alloys. The models are also extended to study
systems with A-site and B-site doping, such as
(Na_{1/2}La_{1/2})(Mg_{1/3}Nb_{2/3})O_3,
(Ba_{1-x}La_{x})(Mg_{(1+x)/3}Nb_{(2-x)/3})O_3 and
(Pb_{1-x}La_{x})(Mg_{(1+x)/3}Ta_{(2-x)/3})O_3. General trends are reproduced by
purely electrostatic interactions, and charge transfer effects indicate that
local structural relaxations can tip the balance between different B-site
orderings in Pb based materials.Comment: 15 pages, 6 figure
Pion-nucleus optical potential valid up to the DELTA-resonance region
We present in this article an optical potential for the -nucleus
interaction that can be used in various studies involving -nucleus
channels. Based on earlier treatments of the low energy -nucleus optical
potential, we have derived a potential expression applicable from threshold up
to the -resonance region. We extracted the impulse approximation form
for this potential from the scattering amplitude and then added to it
kinematical and physical corrections. The kinematic corrections arise from
transforming the impulse approximation expression from the center of
mass frame to the -nucleus center of mass frame, while the physical
corrections arise mostly from the many-body nature of the -nucleus
interaction. By taking advantage of the experimental progress in our knowledge
of the process, we have updated earlier treatments with parameters
calculated from state-of-the-art experimental measurements.Comment: 23 pages, 12 figures. Accepted for publication in Physical Review
Proteomic Analysis of Bacterial Expression Profiles Following Exposure to Organic Solvent Flower Extract of Melastoma candidum D Don (Melastomataceae)
Purpose: To identify potential antibacterial protein targets following exposure to Melastoma candidum extract.Methods: Plant extracts were prepared using sequential extraction method. Denaturing gel electrophoresis and MALDI TOF-TOF MS protein sequencing were used to identify differentialexpressed bacterial proteins. 96-well microplate method was used to determine the minimum inhibitory concentration (MIC) values. Thin layer chromatography (TLC) bio-autobiography and gaschromatography-mass spectrometry (GC-MS) were performed to determine the phytochemicals in the active fraction.Results: Five differentially expressed bacterial proteins (four from Escherichia coli and one from Staphylococcus aureus), were identified via proteomic approach. Among the bacterial proteins identified, glutamate decarboxylase, elongation factor-Tu and α-hemolysin are especially noteworthy, as they are implicated in critical bacterial pathways pertaining to survival in acidic environment, protein translation and virulence, respectively. Additionally, we tested and reported the minimum inhibition concentrations of different M. candidum fractions and gas chromatography-mass spectrometry GC-MS analysis of the active fraction.Conclusion: Glutamate decarboxylase, elongation factor-Tu and α-hemolysin represent potential antibacterial targets.Keywords: Escherichia coli, Staphylococcus aureus, Melastoma candidum, Glutamate decarboxylase, Elongation factor-Tu, α-Hemolysin, Protein expressio
Theory and design of InGaAsBi mid-infrared semiconductor lasers: type-I quantum wells for emission beyond 3 m on InP substrates
We present a theoretical analysis and optimisation of the properties and
performance of mid-infrared semiconductor lasers based on the dilute bismide
alloy InGaAsBi, grown on conventional (001) InP
substrates. The ability to independently vary the epitaxial strain and emission
wavelength in this quaternary alloy provides significant scope for band
structure engineering. Our calculations demonstrate that structures based on
compressively strained InGaAsBi quantum wells (QWs)
can readily achieve emission wavelengths in the 3 -- 5 m range, and that
these QWs have large type-I band offsets. As such, these structures have the
potential to overcome a number of limitations commonly associated with this
application-rich but technologically challenging wavelength range. By
considering structures having (i) fixed QW thickness and variable strain, and
(ii) fixed strain and variable QW thickness, we quantify key trends in the
properties and performance as functions of the alloy composition, structural
properties, and emission wavelength, and on this basis identify routes towards
the realisation of optimised devices for practical applications. Our analysis
suggests that simple laser structures -- incorporating
InGaAsBi QWs and unstrained ternary
InGaAs barriers -- which are compatible with established
epitaxial growth, provide a route to realising InP-based mid-infrared diode
lasers.Comment: Submitted versio
Infrared spectroscopy of phytochrome and model pigments
Fourier-transform infrared difference spectra between the red-absorbing and far-red-absorbing forms of oat phytochrome have been measured in H2O and 2H2O. The difference spectra are compared with infrared spectra of model compounds, i.e. the (5Z,10Z,15Z)- and (5Z,10Z,15E)-isomers of 2,3,7,8,12,13,17,18-octaethyl-bilindion (Et8-bilindion), 2,3-dihydro-2,3,7,8,12,13,17,18-octaethyl-bilindion (H2Et8-bilindion), and protonated H2Et8-bilindion in various solvents. The spectra of the model compounds show that only for the protonated forms can clear differences between the two isomers be detected. Since considerable differences are present between the spectra of Et8-bilindion and H2Et8-bilindion, it is concluded that only the latter compound can serve as a model system of phytochrome. The 2H2O effect on the difference spectrum of phytochrome supports the view that the chromophore in red-absorbing phytochrome is protonated and suggests, in addition, that it is also protonated in far-red-absorbing phytochrome. The spectra show that protonated carboxyl groups are influenced. The small amplitudes in the difference spectra exclude major changes of protein secondary structure
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