Large-eddy simulation of a mildly curved open-channel flow

After validation with experimental data, large-eddy simulation (LES) is used to study in detail the open-channel flow through a curved flume. Based on the LES results, the present paper addresses four issues. Firstly, features of the complex bicellular pattern of the secondary flow, occurring in curved open-channel flows, and its origin are investigated. Secondly, the turbulence characteristics of the flow are studied in detail, incorporating the anisotropy of the turbulence stresses, as well as the distribution of the kinetic energy and the turbulent kinetic energy. Moreover, the implications of the pattern of the production of turbulent kinetic energy is discussed within this context. Thirdly, the distribution of the wall shear stresses at the bottom and sidewalls is computed. Fourthly, the effects of changes in the subgrid-scale model and the boundary conditions are investigated. It turns out that the counter-rotating secondary flow cell near the outer bank is a result of the complex interaction between the spatial distribution of turbulence stresses and centrifugal effects. Moreover, it is found that this outer bank cell forms a region of a local increase of turbulent kinetic energy and of its production. Furthermore, it is shown that the bed shear stresses are amplified in the bend. The distribution of the wall shear stresses is deformed throughout the bend due to curvature. Finally, it is shown that changes in the subgrid-scale model, as well as changes in the boundary conditions, have no strong effect on the result

The effect of migrating dune forms on the flow field of an alluviral river

The bed of an alluvial river is highly susceptible to changes during the course of its existence. Besides variations of the large scale topography and plan form of the river, smaller scale dune forms can be observed. These recurring dune forms migrate on top of the large scale topography and can yield local yet important variations in the flow field. In order to study the effect of migrating dune forms on the flow characteristics and consequently the erosive capacity of an alluvial river, an experiment with mobile bed has been carried out in a laboratory flume representing a sharp meander bend. In this experiment, changes to an initially flat, slightly sloped river bed under a steady flow and sediment discharge were observed until a recurring pattern of migrating dune forms could be seen on top of the characteristic pool-bar topography of meander bends. Once the dune forms were established, an Acoustic Doppler Velocity Profiler (ADVP) was placed in several positions alongside the river bend and used to measure the flow depth and flow characteristics under the influence of the passing dunes. Several times during the experiment, the topography was mapped using laser altimetry on a grid of large spatial resolution in order to isolate the dune forms from the large scale topography and determine the dune characteristics and the dune celerity. In this paper the large scale topography and dune characteristics will be shown and the effect of the migrating dune forms on the flow field and the erosive capacity will be discussed in detail

A Study of Flow Characteristics Near a Channel Confluence Using CCHE 2D/3D Models

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Dominant features in three-dimensional turbulence structure: comparison of non-uniform accelerating and decelerating flows

The results are presented from an experimental study to investigate three-dimensional turbulence structure profiles, including turbulence intensity and Reynolds stress, of different non-uniform open channel flows over smooth bed in subcritical flow regime. In the analysis, the uniform flow profiles have been used to compare with those of the non-uniform flows to investigate their time-averaged spatial flow turbulence structure characteristics. The measured non-uniform velocity profiles are used to verify the von Karman constant κ and to estimate sets of log-law integration constant B r and wake parameter П, where their findings are also compared with values from previous studies. From κ, B r and П findings, it has been found that the log-wake law can sufficiently represent the non-uniform flow in its non-modified form, and all κ, B r and П follow universal rules for different bed roughness conditions. The non-uniform flow experiments also show that both the turbulence intensity and Reynolds stress are governed well by exponential pressure gradient parameter β equations. Their exponential constants are described by quadratic functions in the investigated β range. Through this experimental study, it has been observed that the decelerating flow shows higher empirical constants, in both the turbulence intensity and Reynolds stress compared to the accelerating flow. The decelerating flow also has stronger dominance to determine the flow non-uniformity, because it presents higher Reynolds stress profile than uniform flow, whereas the accelerating flow does not

Expression of basic fibroblast growth factor is associated with poor outcome in non-Hodgkin's lymphoma

It is now clear that angiogenesis and angiogenesis factors are important in the pathogenesis of haematological malignancies. High pretreatment levels of serum basic fibroblast growth factor have been shown to be associated with poor prognosis in patients with non-Hodgkin's lymphoma. The aim of this study was to evaluate whether non-Hodgkin's lymphoma cells express basic fibroblast growth factor and/or its receptor (fibroblast growth factor receptor-1) and whether basic fibroblast growth factor expression correlates with basic fibroblast growth factor serum levels, intratumoral microvessel density, and patient outcome. We measured basic fibroblast growth factor by enzyme-linked immunosorbent assay in sera taken from 58 patients with non-Hodgkin's lymphoma before treatment and in 19 of them also after treatment. Pathological specimens at diagnosis were evaluated by immunohistochemistry staining using polyoclonal antibody against factor-VIII-related antigen, basic fibroblast growth factor and fibroblast growth factor receptor-1 to determine the expression of the microvessel count and basic fibroblast growth factor and fibroblast growth factor receptor-1. The lymphoma specimens demonstrated positive staining for basic fibroblast growth factor (in 23%) and fibroblast growth factor receptor-1 (in 58.5%). The patients who expressed basic fibroblast growth factor had a significantly worse progression-free and overall survival than those who did not (P=0.003 and P=0.03 respectively), while patients expressing fibroblast growth factor receptor-1 were less likely to achieve complete remission than those lacking the receptor (33% vs 65% , P=0.047). There was no correlation of basic fibroblast growth factor staining with either serum basic fibroblast growth factor levels or microvessel count. Basic fibroblast growth factor serum levels did not change significantly after treatment These results suggest that non-Hodgkin's lymphoma specimens express basic fibroblast growth factor and its receptor (fibroblast growth factor receptor-1) and this expression is associated with poor patient outcome