Maximising the RFID benefits at the tyre distribution centre

In recent years the applications of radio frequency identification technology (RFID) in warehousing have gained a great amount of attention as it is a challenging and dynamic environment. Analysing a receiving operation of third party logistic (3PL) operator running a tyre distribution centre, this paper presents a case study of RFID application in the warehouse. The receiving process is enhanced with the RFID technology, which provides contactless identification, less manual data entry errors, instant stock management. Moreover, these benefits could be maximised by the proposed use of the RFID generated data in accounting of costs and services, which is a novel application of the RFID technology

Gerstmann-Sträussler-Scheinker disease revisited: accumulation of covalently-linked multimers of internal prion protein fragments

Despite their phenotypic heterogeneity, most human prion diseases belong to two broadly defined groups: Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). While the structural characteristics of the disease-related proteinase K-resistant prion protein (resPrPD) associated with the CJD group are fairly well established, many features of GSS-associated resPrPD are unclear. Electrophoretic profiles of resPrPD associated with GSS variants typically show 6-8 kDa bands corresponding to the internal PrP fragments as well as a variable number of higher molecular weight bands, the molecular nature of which has not been investigated. Here we have performed systematic studies of purified resPrPD species extracted from GSS cases with the A117V (GSSA117V) and F198S (GSSF198S) PrP gene mutations. The combined analysis based on epitope mapping, deglycosylation treatment and direct amino acid sequencing by mass spectrometry provided a conclusive evidence that high molecular weight resPrPD species seen in electrophoretic profiles represent covalently-linked multimers of the internal ~ 7 and ~ 8 kDa fragments. This finding reveals a mechanism of resPrPD aggregate formation that has not been previously established in prion diseases

Carotenoid-membrane interactions in liposomes : effect of dipolar, monopolar, and nonpolar carotenoids

Electron paramagnetic resonance (EPR) spin-labeling methods were used to study the effects of carotenoids on the physical properties of saturated phosphatidylcholine (PC) membranes to evaluate the contribution of the terminal hydroxyl groups of xanthophyll molecules to the carotenoid-membrane interaction. Effects of the dipolar, terminally dihydroxylated carotenoid lutein on membrane phase transition, fluidity, order, and polarity were compared with those of monopolar (β-cryptoxanthin) and nonpolar (β-carotene) carotenoids. These effects were monitored at the membrane center as a function of the amount of the carotenoid added to the sample and as a function of temperature for fluid-phase membranes. PC membranes with different thickness (from 12 to 22 carbons in alkyl chains) were used. Carotenoids shifted to lower temperatures and broadened the main phase transition of PC membranes. They decreased the membrane fluidity and increased the order of alkyl chains. Carotenoids also increased the hydrophobicity of the membrane interior. These effects were the strongest for lutein, significantly weaker for β-cryptoxanthin, and negligible for β-carotene. They decreased with the increase of the membrane thickness. Presented results suggest that anchoring of carotenoid molecules at the opposite membrane surfaces by polar hydroxyl groups is significant in enhancing their effects on membrane properties. This manuscript also shows the ability of EPR spin-labeling methods to monitor different membrane properties that can be applied in biotechnological studies with the use of liposomes

A Systematic Approach to Confinement in N=1 Supersymmetric Gauge Theories

We give necessary criteria for N=1 supersymmetric theories to be in a smoothly confining phase without chiral symmetry breaking and with a dynamically generated superpotential. Using our general arguments we find all such confining SU and Sp theories with a single gauge group and no tree level superpotential.Comment: 8 pages, LaTe

Uncertainty In Radar-rainfall Composite And Its Impact On Hydrologic Prediction For The Eastern Iowa Flood Of 2008

Key Points A significant potential source of error exists in mosaicked radar-rainfall maps. Different radar calibration offsets lead to misestimation of rainfall amounts. Systematic error in rainfall significantly affects hydrologic predictions. This study addresses a significant potential source of error that exists in radar-rainfall maps that are combined using data from multiple WSR-88D radars of the Next Generation Radar (NEXRAD) national network in the United States. This error stems from different radar calibration offsets that create a border within discontinuous rainfall fields at the equidistance zone among radars. The discontinuity in rainfall fields could lead to misestimation of rainfall over basins and subsequently, to significant errors in streamflow predictions through a hydrologic model. In this study, we produce enhanced radar-rainfall estimates (HN3) based on a novel approach that allows us to reduce the effects of the relative radar calibration bias. We use the relative bias information previously presented in a radar reflectivity comparison study. To investigate the effects of the relative bias adjustment, we evaluate the HN3 and Stage IV radar-rainfall by comparing them with rain gauge data and analyzing their ability to simulate streamflow for an extreme flood case. While the HN3 estimates are statistically comparable to the Stage IV estimates in the rain gauge data comparison, the borderline that identifies discontinuous rainfall fields disappears in the HN3 estimates. We performed hydrological simulations using a physically based, data-intensive, calibration-free, hillslope-link hydrologic model called CUENCAS and demonstrated CUENCAS\u27s ability to accurately simulate flows by comparing results with observed and predicted streamflow generated by the Sacramento (SAC) model. SAC is the operational flood forecast model that has been used by the National Weather Service since 1969, and it was extensively calibrated based on historical data. The simulation results show that the adjustment improves streamflow predictions in the regions where the misestimation of rainfall quantity is considerable. We conclude that systematic error arising from different calibration offsets in rainfall fields can significantly affect hydrologic predictions. ©2013. American Geophysical Union. All Rights Reserved

Late Miocene to present day structural development of the Polish segment of the Outer Carpathians

This paper presents a few pieces of evidence on neotectonic structural evolution of the Polish segment of the Outer Carpathians. During the Late Neogene, structural development was largely controlled by normal faulting and block uplift. However, there are also indications of compressional stress setting, at least during the Pliocene and particularly within the medial and eastern parts of the belt. In the Quaternary, in turn, structural development has been mainly controlled by compressional stress arrangement, with \sigma _{1} orientated roughly perpendicular to the belt. The Pliocene-Quaternary tectonic mobility of the Polish Outer Carpathians has been relatively weak and mostly of thin-skinned character. Normal faults were formed on the margins of intramontane basins and in the western part of the belt. Rates of uplift of individual structures were variable and the amount of uplift was the greatest in the Late Pliocene and Early Quaternary times. Geomorphologically-detected zones of uplift are relatively narrow and arranged subparallel or under small angle in respect to the strike of principal thrusts and frontal parts of large slices. Such an arrangement is interpreted as resulting from the steepening of frontal thrusts due to horizontal compression within the overthrust flysch nappes. This hypothesis is confirmed by the results of recent break-out and GPS studies, as well as by focal solutions of some Outer Carpathian earthquakes

Inter-comparison Of Reflectivity Measurements Between GPM DPR And NEXRAD Radars

This study demonstrates the potential use of the NASA\u27s Global Precipitation Measurement (GPM) Dual-frequency Precipitation Radar (DPR) to examine ground radar (GR) miscalibration and other uncertainty sources (e.g., partial beam blockage). We acquired the GPM Ground Validation System Validation Network reflectivity matchups between the DPR and three GRs (two in Iowa and one in South Dakota) for 2014–2017. We then refined the matching parameters (e.g., time separation) to reduce uncertainty in the matchup samples by analyzing the sensitivity of the matchup statistical properties to changes in these parameters. To reconcile the same observables (i.e., reflectivity) with different observational properties among the space- and ground-based radars, we developed a statistically integrated framework using inter-comparisons of them all with a Monte Carlo simulation. This method verifies the absolute calibration bias estimated from the refined DPR–GR matchups using relative calibration biases between GRs. We found that taking samples with a narrow temporal gap, estimated by actual measurement time of the DPR and GRs, can significantly reduce sample variability. Through inter-comparisons among the DPR and GRs, we observed that reflectivity differences among GRs in a similar environment (e.g., climatology and geography) are likely to be affected primarily by the calibration mismatch. In this case, the inter-comparison results demonstrated good agreement, and we inferred that the differences can be mitigated by calibration bias correction against the DPR. On the other hand, when the disagreement level of the inter-comparison results is significant, the authors found that other factors, such as partial beam blockage even in relatively plain regions, are more dominant than the calibration bias. In fact, the partial beam blockage effects can manifest themselves as a seasonal pattern in the GR inter-comparison results