A case report on incidental finding of thymoma as anterior mediastinal mass

Thymomas are rare tumors in the anterior mediastinum, representing 50% of anterior mediastinal masses and about 20-30% of all mediastinal tumors. They are of unknown etiology; about 50% of patients with thymomas are diagnosed incidentally with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management, the standard primary treatment for these tumors is Thymectomy. We present a case of 55-year female presented with shortness of breath, cough with expectoration and fever for past ten days. Chest x-ray revealed mediastinal widening. CECT chest showed a well-circumscribed heterogeneous solid enhancing mass lesion. FNAC was planned that showed features in favour of thymoma. Biopsy was done that confirmed lymphocyte rich type B thymoma

EVALUATION OF ANTIDEPRESSANT ACTIVITY OF ETHANOLIC EXTRACT OF DIPTERCANTHUS PROSTRATUS NEES

Objective: The major objective of the study is to evaluate the antidepressant activity of ethanolic extract of Dipteracanthus prostratus Nees using rats. The study also aims to assess the effect of the extract on behavioural pattern of treated rats. Methods: The antidepressant activity of the ethanolic extract of Dipteracanthus prostratus was evaluated using Forced swim test (FST). The effect of the extract on the behavioral pattern was assesssed by an Open field test. The oral doses of 500 mg/kg and 250 mg/kg of the extract were fixed after conducting acute toxicity studies. Imipramine (30 mg/kg) was used as the standard. Results: It was observed from the study that the ethanolic extract of Dipteracanthus prostratus at higher concentration showed significantly (p<0.01) reduction in immobility in forced swim test model of depression after repeated administration for 14 d. The results were comparable to the standard drug Imipramine. However, the extract did not any significant activity after acute administration. Neither the ethanolic extract of Dipteracanthus prostratus nor the standard drug imipramine produced any overt behavioural change or motor dysfunction in the open field test. Conclusion: The present study demands a further detailed investigation on the antidepressant and other possible CNS activities of Dipteracanthus prostrates

Green synthesis of magnesium oxide nanoparticles and their antibacterial activity

1210-1215Nanotechnology has prospects of opening new avenues to fight and prevent diseases using atomic-scale tailoring of materials. As the nano revolution emerges, it is imperative to develop “nano‑naturo” links between nanotechnology and green domains of the nature. The present investigation describes the mangrove Rhizophora lamarckii’s property of synthesizing magnesium oxide nanoparticles . The newly synthesized magnesium oxide nanoparticle morphology is nanohexagonal and spherical. The particles range in dimensions between 20 and 50 nm and are crystalline in nature. The functional groups of the mangrove, amine, and alkane are found to act as reductants and stabilizers. The newly synthesized MgO nanoparticles are found to have potent antibacterial activity

A Novel Semi-Active Suspension System for Automobiles Using Jerk-Driven Damper (JDD)

With the new advancements in the vibration control, the control strategies for the controllable semi-active dampers are finding their way as an essential part of vibration isolators, particularly in vehicle suspension systems. An analysis of frequency response for single degree of freedom (1DOF) system gives an attribute to the fact that in a semi-active suspension system, the damping coefficients can be adjusted to improve ride comfort and road handling performances. The systems study includes various type of semi-active suspension systems, employing nonlinear magnetorheological(MR) dampers that are controlled to provide improved vibration isolation. The currently available control strategies for semi-active dampers can be divided into two main groups. The first one is `On-Off' control and second one is `continuous' control of variable dampers. Available control strategies are either proportional to the relative velocity of sprung mass or the acceleration of sprung mass. A new control strategy which is proportional to the jerk produced in sprung mass called Jerk Driven Damper (JDD) is proposed and analyzed by the use of two state 'On-Off' damper. The control strategy for 'JDD' system is extremely simple and it involves very common logic. `JDD' system requires a two state controllable damper and jerk sensor. A brief study on controllable damper and jerk sensors are presented in this thesis

A New Semi-Active Suspension System Based on Jerk Driven Damper (JDD) Control

A new control strategy for semi-active suspension system in a road vehicle called Jerk Driven Damper (JDD) is proposed and analyzed in this paper. The control strategy for JDD system is extremely simple and it involves very common logic. JDD system requires a two state controllable damper and jerk sensor. A semi-active damper is incorporated into a single degree of freedom (1DOF) quarter car model subjected to base excitation. Here, two types of positive amplitude half sinusoidal type speed breakers (severe and smooth) with same height are considered as input to the vehicle. These proposed road inputs are used for study and simulation of passive, sky-hook (SH) control and acceleration driven damper (ADD) suspension systems. The optimality of JDD is examined over SH and ADD control which is observed with both ‘severe’ and ‘smooth’ speed breakers. It is shown that the JDD control shows better reduction in vertical acceleration when the vehicle comes across severe breaker. Later the vertical body acceleration response (comfort objective) of JDD control strategy is compared with various types of well-studied control strategies and shown to have better isolatio

Effect of Temperature on Free Vibration of Functionally Graded Plate With Cutout

Present article performs the parametric study on vibration characteristics of functionally graded (FG) plate with central hole in thermal environment. ANSYS Parametric Design language is used in developing Finite element model and discretization of the material is done using an eight-node serendipity shell element. Displacement field of the present model is developed using first-order shear deformation theory (FOSDT) with six degrees of freedom. Frequency responses are extracted using Block Lanczos eigenvalue extraction method. To show the accurateness of the  model developed convergence study is done for various mesh sizes to obtain the suitable mesh density. Present results which are computed are compared and validated with the previously reported results. Finally, the effect of temperature on various parameters like cut-out size to thickness ratio, cut-out size to side ratio, power law index, side to thickness ratio, boundary conditions are shown through various numerical illustrations

DYNAMIC RESOURCE ALLOCATION USING VIRTUAL MACHINES FOR CLOUD COMPUTING ENVIRONMENT

ABSTRACT Cloud computing allows business customers to scale up and down their resource usage based on needs. Many of the touted gains in the cloud model come from resource multiplexing through virtualization technology. In this paper, we present a system that uses virtualization technology to allocate data center resources dynamically based on application demands and support green computing by optimizing the number of servers in use. We introduce the concept of "skewness" to measure the unevenness in the multi-dimensional resource utilization of a server. By minimizing skewness, we can combine different types of workloads nicely and improve the overall utilization of server resources. We develop a set of heuristics that prevent overload in the system effectively while saving energy used. Trace driven simulation and experiment results demonstrate that our algorithm achieves good performance

Validity of transcutaneous bilirubin in the first few days of life

Objective: To study the validity of transcutaneous bilirubin (TCB) at different time points between 24 and 96 h of life. Materials and Methods: The study was conducted in a tertiary newborn center from November 2014 to June 2016. We have included all babies above 34 weeks of gestation while babies with established direct hyperbilirubinemia, neonatal septicemia, major congenital/gastrointestinal malformations and those on phototherapy were excluded from the study. After taking into consideration the inclusion and exclusion criteria, 396 babies were recruited. The correlation was analyzed using the ROC curves, and r values and plots of agreement were done using Bland Altman charts. Results: A total of 662 paired TCB and serum bilirubin readings were performed in 396 healthy neonates, at designated time points between 24 and 96 h of life. Mean TCB was found to be uniformly higher than total serum bilirubin (TSB) for all variables such as sex, birth weight, gestational age, and growth of the baby with an excellent correlation (r=0.698-0.932). The correlation between TCB and serum bilirubin improved as age increased with maximum correlation at 96 h (r=0.981). Test of agreement showed that at 24 h the TCB overestimated serum bilirubin by 1.5±0.7 mg/dl which decreased to 0.8±0.6 mg/dl by 96 h. Conclusion: TCB and TSB correlated significantly between 24 and 96 h of age. However, there is overestimation by TCB initially which decreases at 96 h

Real-Time Tracking of Wildlife with IoT Solutions in Movement Ecology

Movement ecology has grown increasingly significant in the backdrop of global environmental changes, emphasizing the importance of understanding animal mobility patterns. The integration of Internet of Things (IoT) technology offers transformative potential for real-time wildlife tracking, addressing limitations of traditional methods like radio telemetry. Through IoT devices, researchers can acquire immediate, high-resolution datasets spanning vast distances, capturing multiple data points such as environmental conditions and physiological parameters. Existing implementations range from monitoring elephant movements in Africa to observing bird migrations. However, while promising, challenges like battery longevity, device weight, data management, and animal safety persist. As technological advances emerge, future prospects include more efficient, integrated solutions combining IoT with other technologies, poised to reshape and enrich our understanding of wildlife movement