Assessment of knowledge, attitude and practice of reporting of adverse drug reaction among family physicians in Surat city

Background: Majority of the patients first contact the family physicians (FP) for treatment. If adverse drug reaction (ADR) occurs necessary measures are taken and ADR managed but usually not reported. The present study was conducted to assess knowledge, attitude and practice of reporting of ADR among family physicians.Methods: The study was a prospective cross-sectional questionnaire based study. The correctly filled forms from 90 family physicians were analysed based on 20 questions (knowledge 10, attitude 5, and practice 5).Results: Majority of family physicians were aware regarding the occurrence of ADR and 59% of them were aware that all ADR should be reported. Most of (71%) the physicians do not know there is ADR reporting form. Majority of them (93%) are aware that reporting of ADR is necessary that will increase patient safety (92%). About 78% of physician were aware that ADR can be reported by any of health care professional. However, about 71% do not know how to report and where to report ADR. Only few of them (19%) have reported ADR.Conclusions: The family physicians of Surat have adequate knowledge about pharmacovigilance and aware that ADR should be reported. However, most of them have not reported any ADR due to various reasons

Three-dimensional linear instability in pressure-driven two-layer channel flow of a Newtonian and a Herschel-Bulkley fluid

The three-dimensional linear stability characteristics of pressure-driven two-layer channel flow are considered, wherein a Newtonian fluid layer overlies a layer of a Herschel-Bulkley fluid. We focus on the parameter ranges for which Squire's theorem for the two-layer Newtonian problem does not exist. The modified Orr-Sommerfeld and Squire equations in each layer are derived and solved using an efficient spectral collocation method. Our results demonstrate the presence of three-dimensional instabilities for situations where the square root of the viscosity ratio is larger than the thickness ratio of the two layers; these "interfacial" mode instabilities are also present when density stratification is destabilizing. These results may be of particular interest to researchers studying the transient growth and nonlinear stability of two-fluid non-Newtonian flows. We also show that the "shear" modes, which are present at sufficiently large Reynolds numbers, are most unstable to two-dimensional disturbances

Evaporating Falling Drop

There-dimensional numerical simulations are carried out to investigate the dynamics of a drop undergoing evaporation and falling due to gravity. In order to accurately capture the interfacial phenomena dynamic adaptive grid refinement has been incorporated. The results are presented in terms of spatio-temporal evolution of the shape of the drop, along with the contours of the vapour concentration generated due to evaporation. This study has implications in natural phenomena, such as rainfall, dew formation and several industrial applications undergoing phase change. A parametric study of this phenomenon will be presented at the conference

Pseudo Random Generator Based Public Key Cryptography

Advances in communication technology have seen strong interest in digital data transmission. However, illegal data access has become more easy and prevalent in wireless and general communication networks. In order to protect the valuable data from illegal access, different kinds of cryptographic systems have been proposed. In this paper, a new integrating channel coding and cryptography design communication systems is proposed. So we use cryptography as an error detection tool. In order to preserve the advantages of encryption and to improve its disadvantages, we place the encryptor before the encoder. The hamming encoder is used to select the generator matrix to be used as a block code to form the new system .In this the security of common cryptographic primitive i.e a key stream generator based on LFSR can be strengthened by using the properties of a physical layer.So, a passive eaves dropping will experience great difficulty in cracking the LFSR based cryptography system as the computational complexity of discovering the secret key increases to large extent. The analysis indicates that the proposed design possesses the following feature. Its security is higher than the conventional one with the channel encoder only. Privacy is more due to unknown random codes. As the applied codes are unknown to a hostile user, this means that it is hardly possible to detect the message of another user. Anti-jam performance is good. It overcomes the disadvantage of Chaos based cryptography system as input data is not extended and hence bandwidth is not wasted. Moreover, the computer simulation shows that the proposed system has a good ability in error detection especially when the SNR per bit is moderate high, and the detection ability is enhanced when the increased length of Hamming code is employed

A New Approach of Cryptographic Technique Using Simple ECC ECF

Cryptography is the technique in which usually a file is converted into unreadable format by using public key and private key system called as public key cryptosystem. Then as per the user requirement that file is send to another user for secure data transmission. In this paper we purposed an image based cryptography that Elliptic Curve Function (ECF) techniques and pseudo random encoding technique on images to enhance the security of RFID communication. In the ECF approach, the basic idea is to replace the Elliptic Curve Function (ECF) of the cover image with the Bits of the messages to be hidden without destroying the property of the cover image significantly. The ECF based technique is the most challenging one as it is difficult to differentiate between the cover object and Crypto object if few ECF bits of the cover object are replaced. In Pseudo Random technique, a random key is used as seed for the Pseudo Random Number Generator in needed in the embedding process. Both the techniques used a Crypto key while embedding messages inside the cover image. By using the key, the chance of getting attacked by the attacker is reduced

Numerical prediction and experimental validation of sound transmission loss for different acoustic materials

This paper examines the sound transmission loss (STL) through multilayer panel materials commonly used in the building industry. The acoustic characteristics of different materials and multilayer panels are studied. Experimental data for the noise reduction coefficient in the frequency range 100 to 4000 Hz have been obtained using the two room’s method.  Mass theory is also used to predict the acoustic performance of these systems and to improve their acoustic performance with noise treatment

Impact of weather parameters on cotton productivity at Surat (Gujarat), India

Global warming is casting its shadow in the form of climatic changes that is affecting the local weather conditions which has its bearing on crop production and water availability, the basic necessities for survival of life on the planet. In the present study, an attempt was made to investigate the cause of poor production of cotton in 2011-12 in Surat, Gujarat as compared to 2012-13 and 2013-14. Weather data since 2000 was analyzed and compared with the data of 2011-12 and comparison was made to find the abnormality in cotton crop productivity. It was found that during 2011-12, there was delayed monsoon, as well as during squaring and flowering stage (i.e. in August 2011) there was high rainfall (595.6 mm), maximum and minimum temperatures were above normal, during development (June-August) and flowering stage of crop (October-December) which disturbed the crop physiology indirectly affecting the yield of cotton. The combined effect of rainfall and temperature was on relative humidity that created conducive atmosphere for insect and pest attacks on crops. Due to changes in temperature and relative humidity, evaporative water demands would have further aggravated the watering needs of crop. The study concludes that erratic monsoon or delayed monsoon hampers crop physiology ultimately yield due to erratic weather conditions. Further, such changes in cotton growing areas could form the basis of planning and decisions on pricing, crop insurance, export and import policies of cotton crop

A study of effect of a single dose of second generation antihistaminics on cognitive and psychomotor function in healthy human volunteers

Background: Objective of the study was to assess whether second generation antihistaminic alter psychomotor and cognitive function in comparison with promethazine (marked sedation; altered psychomotor and cognitive impairment).Methods: It was a single blind prospective study. Seventy five healthy human volunteers were registered, divided in five groups. These groups have received placebo, promethazine 25 mg, cetirizine 10 mg, fexofenadine 120 mg and loratadine 10 mg. Cognitive and psychomotor functions were assessed pretreatment and 60 minutes after single dose of drug(post treatment)by using a battery of standard tests (e.g. PST-Perceptual speed test, BVRT-Benton visual retention test,SSS- Stanford Sleepiness Scale, FTT-Finger tapping test etc.). The data were analyzed by student’s t-test and ANOVA test.Results: No significant effect was observed in any test parameter with placebo and fexofenadine. Significant difference with promethazine in PST, BVRT, SSS and cetirizine in DSST, FTT and loratadine in DSST were observed. Significant difference was observed in DSST between the placebo and promethazine, in SSS between promethazine and all other drugs. In FTT and BVRT significant difference between the groups were observed.Conclusions: Significant sedation and altered cognitive and psychomotor function were observed with promethazine. Cetirizine and loratadine do not cause sedation but both affect psychomotor functions. No significant effect was produced by fexofenadine. Thus, fexofenadine can safely be used in persons involved in activity where alertness is required while cetirizine and loratadine should be avoided