Idiopathic Fascicular Ventricular Tachycardia

Idiopathic fascicular ventricular tachycardia is an important cardiac arrhythmia with specific electrocardiographic features and therapeutic options. It is characterized by relatively narrow QRS complex and right bundle branch block pattern. The QRS axis depends on which fascicle is involved in the re-entry. Left axis deviation is noted with left posterior fascicular tachycardia and right axis deviation with left anterior fascicular tachycardia. A left septal fascicular tachycardia with normal axis has also been described. Fascicular tachycardia is usually seen in individuals without structural heart disease. Response to verapamil is an important feature of fascicular tachycardia. Rare instances of termination with intravenous adenosine have also been noted. A presystolic or diastolic potential preceding the QRS, presumed to originate from the Purkinje fibers can be recorded during sinus rhythm and ventricular tachycardia in many patients with fascicular tachycardia. This potential (P potential) has been used as a guide to catheter ablation. Prompt recognition of fascicular tachycardia especially in the emergency department is very important. It is one of the eminently ablatable ventricular tachycardias. Primary ablation has been reported to have a higher success, lesser procedure time and fluoroscopy time

Semi-supervised and Active-learning Scenarios: Efficient Acoustic Model Refinement for a Low Resource Indian Language

We address the problem of efficient acoustic-model refinement (continuous retraining) using semi-supervised and active learning for a low resource Indian language, wherein the low resource constraints are having i) a small labeled corpus from which to train a baseline `seed' acoustic model and ii) a large training corpus without orthographic labeling or from which to perform a data selection for manual labeling at low costs. The proposed semi-supervised learning decodes the unlabeled large training corpus using the seed model and through various protocols, selects the decoded utterances with high reliability using confidence levels (that correlate to the WER of the decoded utterances) and iterative bootstrapping. The proposed active learning protocol uses confidence level based metric to select the decoded utterances from the large unlabeled corpus for further labeling. The semi-supervised learning protocols can offer a WER reduction, from a poorly trained seed model, by as much as 50% of the best WER-reduction realizable from the seed model's WER, if the large corpus were labeled and used for acoustic-model training. The active learning protocols allow that only 60% of the entire training corpus be manually labeled, to reach the same performance as the entire data

Dynamic Analysis and Design of Motorcycle Mounting System Subjected to Road Loads

This paper presents a comprehensive model of a motorcycle mounting system. The model presented herein consists of two main assemblies. The powertrain assembly and the swing-arm assembly are modeled as a six degree of freedom rigid bodies. The two assemblies are connected to each other using a shaft that is usually referred to as the coupler. The connection points on both assemblies are known.Unlike automobiles, motorcycle performance and handling is highly affected by the external disturbance. In addition to minimizing the shaking loads, the mounting system must be set up such that it also minimizes the external disturbance from the environment such as irregularities in the road profile and road bumps. This disturbance can be transmitted through the tire patch to the engine causing it to hit nearby components. The engine movement needs to be minimized due to space limitations surrounding the engine. In order to do so, these transmitted external loads must be minimized by the use of the mounting system. The load minimization process is achieved by selecting the optimum stiffness parameters, location and orientation of the mounting system that are supporting the engine. This goal is achieved by an optimization scheme that guarantees that the transmitted loads are minimized. An investigation will be done to explore the effect of different road profiles on the mount final geometrical shape

A note on observations on cetaceans in the western Indian sector of the Southern Ocean (20-56°S and 45-57°30’E), January to March 2004

A multi-disciplinary and multi-institutional pilot expedition was organised by the National Centre for Antarctic and Ocean Research (NCAOR) to the ice-free areas of the Western Indian Ocean sector of the Southern Ocean onboard ORV Sagar Kanya during the austral summer of 2004 (January-March). This survey, conducted by the Central Marine Fisheries Research Institute (CMFRI), is the first Indian attempt to survey for cetacean diversity in the Southern Ocean. The ultimate objective is to determine distribution, relative abundance, migration patterns and critical habitat parameters. 68% of a total of 13 sightings (22 individuals) were positively identified and species observed included Antarctic minke whales (Balaenoptera bonaerensis), fin whales (B. physalus), sei whales (B. borealis) and blue whales (B. musculus). The blue whales were not identified to the sub-species level. The highest concentration of cetaceans was between 35° and 37°S (along 45°E) and between 48° and 53°S (along 45°E). Relatively small numbers of cetaceans were observed during the present cruise, possibly because most of the cetacean sighting effort was made during inclement sea conditions. Results on the sighting characteristics and occurrence patterns of the cetaceans in relation to the region and hydrographical parameters are discussed briefly vis a vis published information from the Southern Ocean

Partial purification and characterisation of some low molecular weight á - amylases from Dolichos biflorus

Dolichos biflorus, a commonly used legume in Uttarakhand, produces alpha amylase enzyme for conversion of starch present in its cotyledons to glucose, so that this glucose can be further utilized for the life controlling processes, glycolysis and Kreb’s cycle. Yield of this á - amylase isolated from the germinating legume comes out to be 27.7 IUml-1. Maximal amylase production occurs at pH 6.1 at 45O C. The enzyme was purified two fold, first with ultra-filtration and then with Ion-exchange chromatography. Ultra-filtration revealed size of amylase to be between 10 kDa and 30 kDa, against larger sizes of other bacterial amylases. The pH and temperature optima for purified enzyme were 6.1 and 45OC respectively. The Km for starch came out to be 1.95 mgml-1. This finding of generating one more new and low-price source of á - amylase is a great advancement in biotechnology

A note on cetacean distribution in the Indian EEZ and contiguous seas during 2003-07

Relatively little is known about the distribution of cetaceans in Indian seas due to lack of systematic surveys. For collecting data on species distribution, 35 opportunistic surveys were conducted onboard FORV Sagar Sampada between October 2003 and February 2007 in the Indian EEZ and contiguous seas. In 5,254 hours of sighting effort, a total of 473 cetacean records were made with 5,865 individuals. The occurrence of 10 species from three cetacean families was confirmed. The Indo-Pacific bottlenose dolphin was the most frequently sighted species, whereas the spinner dolphin was dominant in terms of abundance. Long-beaked common dolphins, Indo-Pacific hump-backed dolphin and sperm whales were also recorded at frequent intervals. Cetaceans were found to have a wide geographical distribution in the Indian EEZ and contiguous seas. High abundance and species richness were recorded in the Southeastern Arabian Sea and southern Sri Lankan waters. From the information collected during the present study, the platform of opportunity has proved to be a useful means for cetacean surve

Indian Efforts on the Inventorization of Marine Mammal Species for their Conservation and Management

The present study is the first attempt to use molecular tools for identification of marine mammals in India. The objective was to develop a database of genetic sequences for future marine mammal research in addition to confirming the species identity of cetaceans and dugongs using a molecular approach. Partial sequencing of mitochondrial DNA loci was carried out in accidentally caught/stranded specimens of Spinner dolphin (Stenella longirostris), Pantropical spotted dolphin/bridled dolphin (Stenella attenuata), Bottlenose dolphin (Tursiops aduncus), Long-beaked common dolphin (Delphinus capensis), Indopacific humpbacked dolphin (Sousa chinensis), Risso’s dolphin (Grampus griseus), Finless porpoise (Neophocaena phocaenoides), Sperm whale (Physeter macrocephalus), Blue whale (Balaenoptera musculus), Bryde’s whale (Balaenoptera edeni) and Dugong (Dugong dugon). Molecular identification of species was done by phylogenetic reconstruction of the sequences using portals GenBank and DNA Surveillance. Apart from ratifying their morphological identification, the analysis was able to distinguish specimens that otherwise, could not have been identified using conventional approaches. Phylogenetic analysis of the Sousa-Stenella-Tursiops-Delphinus group indicated more or less robust monophyly for all species in this complex, except Delphinus capensis. A sister-group relationship for Sperm whales and Baleen whales was evident, that would place the former closer to the latter than to any other group of toothed whales

Effect of chelating agents on phytoextraction of Ni from contaminated Soil by Zea mays

The effects of application of CDTA, (CA), DTPA, NTA and FYM on the growth of Zea mays and its Ni uptake and accumulation were investigated using the pot-culture experiments. Application of chelating agents decreased the dry matter yield of roots of Zea mays while, higher values of dry matter yield (11.35 g pot-1) was observedin case of FYM sewage sludge amended soil at 80 days after sowing. FYM addition was found beneficial as compared to control (Ni90). Dry matter yield of shoots of Zea mays increased over control due to application of CDTA and FYM. The highest value of dry matter yield of shoot (86.05 g pot-1) was observed in case of CDTA withsewage sludge amended soil at 80 days after sowing. Whereas reverse trend was observed in NTA, CA and DTPA treated soils. Chelating agents enhanced the Ni uptake by both roots and shoots, higher values of Ni uptake by roots (3415.44 ?g pot-1 ) and shoots (10104.98 ?g pot-1 ) Was observed in NTA and CDTA treated soil after 80 days of sowing in amended as compared to sewage sludge unamended soil. Application of CDTA followed by NTA was found more effective in enhancing the Ni uptake by Zea mays roots and shoots than any other chelating agents at both the growth stages. The chelating agents are found useful in enhancing phytoextractability of Ni by Zea mays. Hence, marginally Ni contaminated soil may be remediated by adding chelating agents