Bioefficacy of Imidacloprid 350 SC against sucking insect-pests in chilli (Capsicum annum L.)

A field experiment was conducted in a RBD at Horticulture farm, Rajasthan College of Agriculture, Udaipur to evaluate the bioefficacy of Imidacloprid 350 SC at 100, 125 and 150 ml/ha against sucking pests of chilli during Kharif, 2013 and 2014. The highest reduction in the population of aphid, jassids and thrips in chilli was recorded in case of two spray of Imidacloprid 350 SC at 150 ml/ha and also recorded highest marketable yield of 161.25 and 164.88 q/ha during 2013 and 2014, respectively. It was found at par to Imidacloprid 350 SC at 125 ml/ha

Higher Education Growth in India : Is growth appreciable and comparable?

The Indian higher education system is the largest in the world in terms of the number of institutions and second largest in enrollments. About 33.3 million students are currently enrolled in higher education institutions, but the Gross Enrollment Ratio (GER) is still very low at 23.6%. There are about 757 universities and 38,056 colleges in India. This mammoth network of higher education institutions include a large private sector that has emerged and experienced very rapid growth during last two decades. Despite this growth, Indian higher education is facing several challenges with regard to equity, efficiency and quality. It is still not inclusive, globally competitive, and innovative. The present paper examines the Indian higher education growth deception in this context and vindicate the imperative need for effective intervention policies

Reflections on changing landscape of private higher education space in Indian higher education

Higher education is now widely accepted as a foremost instrument for fostering economic growth. The Indian higher education system is the largest in the world in terms of the number of institutions and the second largest in enrollments. About 29.6 million students are currently enrolled in higher education institutions in India. There are around 712 universities and 36,671 colleges in India. This mammoth network of higher education institutions includes a large private sector that has emerged explicitly and outsized during last two decades. The overall share of the unaided private higher education institutions has reached 63.9 percent, and the share of student enrollments in these institutions has reached 58.9 percent. The authors make an attempt to present an overview of Indian higher education and within the same frame tries to delineate and identify the advent and growth of private higher education

Bioefficacy of different Insecticides against aphid (Myzus persicae) in cumin (Cuminum cyminum L.)

A field trail was conducted in randomized block design at KVK Bhilwara, MPUAT, Udaipur to evaluate efficacy of carbosulfan 25% EC at 250, 312.5 and 375 g a.i. ha-1 along with thiamethoxam 25% WG at 25 g a.i. ha-1, imidacloprid 17.8 SL at 25 g a.i. ha-1 and acetamiprid 20% SP at 10 g a.i. ha-1 against aphid (Myzus persicae) in cumin during Rabi, 2013-14 and 2014-15. The result revealed that two sprays of carbosulfan 25% EC at 375 g a.i. ha-1 was found effective against aphid. It caused maximum mean reduction in thrips population after second spray at 10 days after application, which was 87.52% and 88.45% during 2013-14 and 2014-15, respectively. It was followed by carbosulfan 25% EC at 312.5 g a.i. ha-1. The maximum yields were recorded in case of carbosulfan 25% EC at 375 g a.i. ha-1, which were 622.3 and 456.7 kg ha-1 during 2013-14 and 2014-15, respectively and incremental yield of 358.6 kg ha-1 over untreated control

Systems Biology and Birth Defects Prevention: Blockade of the Glucocorticoid Receptor Prevents Arsenic-Induced Birth Defects

Background: The biological mechanisms by which environmental metals are associated with birth defects are largely unknown. Systems biology–based approaches may help to identify key pathways that mediate metal-induced birth defects as well as potential targets for prevention

Kulturelna i metagenomska identifikacija mikrobioma kod supkliničkog mastitisa u krava.

Metagenomic and traditional microbial culture based analyses of milk samples from cows harbouring subclinical mastitis pathogens were carried out to identify the microbial community structure of milk. A total of 77 Triple cross (TP), Kankrej and Gir lactating cows and 301 quarters were screened for subclinical mastitis. A total of 106 isolates belonging to five different microbial genera were recovered from 91 quarters of 41 cows, including 15 quarters having mixed bacterial infections by cultural examination. Pyrosequencing readings obtained from the breed wise pooled DNA of subclinical mastitis milk samples were analyzed using the SEED subsystem database of Meta Genome Rapid Annotation with Subsystem Technology (MG-RAST). Among the five genera, Staphylococcus, Streptococcus, Micrococcus, Bacillus and Escherichia, detected in the subclinical mastitis milk samples by culture based methods, four genera, Staphylococcus, Streptococcus, Bacillus and Escherichia, were identified in the corresponding pyrosequencing data, while Micrococcus was not found. In contrast, the pyrosequencing yielded 28 bacterial species, of which only two species, S. aureus and E. coli, were identified by the cultural method. S. agalactiae, the third species identified by cultural method, was not found in the pyrosequencing data. Metagenomic analysis additionally identified 19 genera and 26 species in comparison with the routine cultural methods. Many of the fastidious / anaerobic bacterial organisms, which are difficult to cultivate by routine methods, were identified by metagenomic analyses.Radi identifikacije mikrobne zajednice u mlijeku provedena je metagenomska i uobičajena kulturelna pretraga uzoraka mlijeka krava sa supkliničkim mastitisom. Ukupno je 77 trostruko križanih Kankrej i Gir mliječnih krava i 301 četvrt vimena bilo pretraženo na supklinički mastitis. Izdvojeno je bilo 106 izolata svrstanih u pet različitih rodova iz 91 četvrti od 41 krave uključujući i 15 četvrti kod kojih je kulturelnom pretragom bila ustanovljena mješovita bakterijska infekcija. Sljedovi mješavine DNA izdvojeni iz uzoraka mlijeka kod supkliničkog mastitisa očitani pirosekvenciranjem bili su analizirani po podsustavu SEED baze podataka „Meta Genome Rapid Annotation with Subsystem Technology (MG-RAST)“. Iz pretraženih uzoraka mlijeka bilo je izdvojeno pet rodova: Staphylococcus, Streptococcus, Micrococcus, Bacillus i Escherichia. Četiri su bila dokazana postupkom pirosekvenciranja: Staphylococcus, Streptococcus, Bacillus i Escherichia, dok Micrococcus nije bio dokazan. S druge strane, pirosekvenciranjem je bilo dokazano 28 bakterijskih vrsta, od kojih su samo dvije, S. aureus i E. coli, bile dokazane klasičnom kulturelnom pretragom. S. agalactiae, treća vrsta identificirana kulturelnom pretragom nije bila dokazana postupkom pirosekvenciranja. Metagenomskom analizom dodatno je bilo dokazano 19 rodova i 26 vrsta u usporedbi s rutinskom kulturelnom pretragom. Mnoge anaerobne bakterije, koje je vrlo teško uzgojiti rutinskim metodama, bile su identificirane metagenomskom analizom

Effect of Conductive Filament Temperature on ZrO2 based Resistive Random Access Memory Devices

In the present work, the effect of reset voltage, filament radius, filament resistivity, and oxide membrane thickness on the nanoscale ZrO2 RRAM devices was reported. The present investigation is based on the thermal reaction model of RRAM. The outcomes show a decline in saturated temperature with a rise in the radius and resistivity of filament. Furthermore, increases in saturated temperature with an increase in oxide membrane thickness were observed for the ZrO2 based RRAM device. The saturated temperature of the device was mainly influenced by reset voltage, oxide layer thickness, filament size, and filament resistivity. The simulation results of the present investigation can be beneficial for the optimization of RRAM devices

Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300

MicroRNAs play an important role in the regulation of mRNA translation and have therapeutic potential in cancer and other diseases. To profile the landscape of microRNAs with significant cytotoxicity in the context of glioblastoma (GBM), we performed a high-throughput screen in adult and pediatric GBM cells using a synthetic oligonucleotide library representing all known human microRNAs. Bioinformatics analysis was used to refine this list and the top seven microRNAs were validated in a larger panel of GBM cells using state-of-the-art in vitro assays. The cytotoxic effect of our most relevant candidate was assessed in a preclinical model. Our screen identified ~100 significantly cytotoxic microRNAs with 70% concordance between cell lines. MicroRNA-1300 (miR-1300) was the most potent and robust candidate. We observed a striking binucleated phenotype in miR-1300 transfected cells due to cytokinesis failure followed by apoptosis. This was also observed in two stem-like patient-derived cultures. We identified the physiological role of miR-1300 as a regulator of endomitosis in megakaryocyte differentiation where blockade of cytokinesis is an essential step. In GBM cells, where miR-1300 is normally not expressed, the oncogene Epithelial Cell Transforming 2 (ECT2) was validated as a direct key target. ECT2 siRNA phenocopied the effects of miR-1300, and ECT2 overexpression led to rescue of miR-1300 induced binucleation. We showed that ectopic expression of miR-1300 led to decreased tumor growth in an orthotopic GBM model. Our screen provides a resource for the neuro-oncology community and identified miR-1300 as a novel regulator of endomitosis with translatable potential for therapeutic application