16 research outputs found
Vison gap in the Rokhsar-Kivelson dimer model on the triangular lattice
With the classical Monte Carlo method, I find the energy gap in the
Rokhsar-Kivelson dimer model on the triangular lattice. I identify the lowest
excitations as visons, and compute their energy as a function of the momentum.Comment: 5 page
MCA: Multiresolution Correlation Analysis, a graphical tool for subpopulation identification in single-cell gene expression data
Background: Biological data often originate from samples containing mixtures
of subpopulations, corresponding e.g. to distinct cellular phenotypes. However,
identification of distinct subpopulations may be difficult if biological
measurements yield distributions that are not easily separable. Results: We
present Multiresolution Correlation Analysis (MCA), a method for visually
identifying subpopulations based on the local pairwise correlation between
covariates, without needing to define an a priori interaction scale. We
demonstrate that MCA facilitates the identification of differentially regulated
subpopulations in simulated data from a small gene regulatory network, followed
by application to previously published single-cell qPCR data from mouse
embryonic stem cells. We show that MCA recovers previously identified
subpopulations, provides additional insight into the underlying correlation
structure, reveals potentially spurious compartmentalizations, and provides
insight into novel subpopulations. Conclusions: MCA is a useful method for the
identification of subpopulations in low-dimensional expression data, as
emerging from qPCR or FACS measurements. With MCA it is possible to investigate
the robustness of covariate correlations with respect subpopulations,
graphically identify outliers, and identify factors contributing to
differential regulation between pairs of covariates. MCA thus provides a
framework for investigation of expression correlations for genes of interests
and biological hypothesis generation.Comment: BioVis 2014 conferenc
A case study on the use of scale separation-based analytic propagators for parameter inference in stochastic gene regulation
Full Counting Statistics and Field Theory
We review the relations between the full counting statistics and the field
theory of electric circuits. We demonstrate that for large conductances the
counting statistics is determined by non-trivial saddle-point of the field.
Coulomb effects in this limit are presented as quantum corrections that can
stongly renormalize the action at low energies.Comment: microreview, 15 pages, accepted to Ann. Phys. (Leipzig
Metastability in zero-temperature dynamics: Statistics of attractors
The zero-temperature dynamics of simple models such as Ising ferromagnets
provides, as an alternative to the mean-field situation, interesting examples
of dynamical systems with many attractors (absorbing configurations, blocked
configurations, zero-temperature metastable states). After a brief review of
metastability in the mean-field ferromagnet and of the droplet picture, we
focus our attention onto zero-temperature single-spin-flip dynamics of
ferromagnetic Ising models. The situations leading to metastability are
characterized. The statistics and the spatial structure of the attractors thus
obtained are investigated, and put in perspective with uniform a priori
ensembles. We review the vast amount of exact results available in one
dimension, and present original results on the square and honeycomb lattices.Comment: 21 pages, 6 figures. To appear in special issue of JPCM on Granular
Matter edited by M. Nicodem
Quasi-long-range order in the random anisotropy Heisenberg model: functional renormalization group in 4-\epsilon dimensions
The large distance behaviors of the random field and random anisotropy O(N)
models are studied with the functional renormalization group in 4-\epsilon
dimensions. The random anisotropy Heisenberg (N=3) model is found to have a
phase with the infinite correlation radius at low temperatures and weak
disorder. The correlation function of the magnetization obeys a power law <
m(x) m(y) >\sim |x-y|^{-0.62\epsilon}. The magnetic susceptibility diverges at
low fields as \chi \sim H^{-1+0.15\epsilon}. In the random field O(N) model the
correlation radius is found to be finite at the arbitrarily weak disorder for
any N>3. The random field case is studied with a new simple method, based on a
rigorous inequality. This approach allows one to avoid the integration of the
functional renormalization group equations.Comment: 12 pages, RevTeX; a minor change in the list of reference
Critical fluctuations and breakdown of Stokes-Einstein relation in the Mode-Coupling Theory of glasses
We argue that the critical dynamical fluctuations predicted by the
mode-coupling theory (MCT) of glasses provide a natural mechanism to explain
the breakdown of the Stokes-Einstein relation. This breakdown, observed
numerically and experimentally in a region where MCT should hold, is one of the
major difficulty of the theory, for which we propose a natural resolution based
on the recent interpretation of the MCT transition as a bona fide critical
point with a diverging length scale. We also show that the upper critical
dimension of MCT is d_c=8.Comment: Proceedings of the workshop on non-equilibrium phenomena in
supercooled fluids, glasses and amorphous materials (17-22 September, 2006,
Pisa
Moving glass theory of driven lattices with disorder
We study periodic structures, such as vortex lattices, moving in a random
potential. As predicted in [T. Giamarchi, P. Le Doussal Phys. Rev. Lett. 76
3408 (1996)] the periodicity in the direction transverse to motion leads to a
new class of driven systems: the Moving Glasses. We analyse using several RG
techniques the properties at T=0 and : (i) decay of translational long
range order (ii) particles flow along static channels (iii) the channel pattern
is highly correlated (iv) barriers to transverse motion. We demonstrate the
existence of the ``transverse critical force'' at T=0. A ``static random
force'' is shown to be generated by motion. Displacements grow logarithmically
in and algebraically in . The persistence of quasi long range
translational order in at weak disorder, or large velocity leads to
predict a topologically ordered ``Moving Bragg Glass''. This state continues
the static Bragg glass and is stable at , with non linear transverse
response and linear asymptotic behavior. In , or in at intermediate
disorder, another moving glass exist (the Moving Transverse Glass) with smectic
quasi order in the transverse direction. A phase diagram in force and
disorder for static and moving structures is proposed. For correlated disorder
we predict a ``moving Bose glass'' state with anisotropic transverse Meissner
effect and transverse pinning. We discuss experimental consequences such as
anomalous Hall effect in Wigner crystal and transverse critical current in
vortex lattice.Comment: 74 pages, 27 figures, RevTe
Additional file 1 of Inference of spatiotemporal effects on cellular state transitions from time-lapse microscopy
Supplementary Text. This document provides a detailed description of the full probabilistic model, Bayesian credibility intervals, the proof of sample independence, and the relation of log-binomial and Poisson regression. (PDF 345 kb