A biomechanical analysis of the farmers walk, and comparison with the deadlift and unloaded walk

This study compared the biomechanical characteristics of the farmers walk, deadlift and unloaded walk. Six experienced male strongman athletes performed farmers' walks and deadlifts at 70% of their 1RM deadlift. Significant differences (p < 0.05) were apparent at knees passing with the farmers lift demonstrating greater trunk extension, thigh angle, knee flexion and ankle dorsiflexion. Significantly greater mean vertical and anterior forces were observed in the farmers lift than deadlift. The farmers walk demonstrated significantly greater peak forces and stride rates and significantly shorter stride lengths, ground contact times, and swing times than unloaded walk. Significantly greater dorsiflexion, knee flexion, thigh angle, and significantly lesser trunk angle at foot strike were also observed in the farmers walk. The farmers lift may be an effective lifting alternative to the deadlift, to generating more anterior-propulsive and vertical force with less stress to the lumbar spine due to the more vertical trunk position

ON THE LARGE ORDER ASYMPTOTICS OF THE WAVE FUNCTION PERTURBATION THEORY

The problem of finding the large order asymptotics for the eigenfunction perturbation theory in quantum mechanics is studied. The relation between the wave function argument x and the number of perturbation theory order k that allows us to construct the asymptotics by saddle-point technique is found: $x/k^{1/2}=const$, k is large. Classical euclidean solutions starting from the classical vacuum play an important role in constructing such asymptotics. The correspondence between the trajectory end and the parameter $x/k^{1/2}$ is found. The obtained results can be applied to the calculation of the main values of the observables depending on k in the k-th order of perturbation theory at larges k and, probably, to the multiparticle production problem.Comment: 9 pages, LaTeX, 1 figure can be obtained from the autho

A high-throughput screening method for determining the substrate scope of nitrilases

Nitrile compounds are intermediates in the synthesis of pharmaceuticals such as atorvastatin. We have developed a chromogenic reagent to screen for nitrilase activity as an alternative to Nessler's reagent. It produces a semi-quantifiable blue colour and hydrolysis of 38 nitrile substrates by 23 nitrilases as cell-free extracts has been shown

Relaxed Schedulers Can Efficiently Parallelize Iterative Algorithms

There has been significant progress in understanding the parallelism inherent to iterative sequential algorithms: for many classic algorithms, the depth of the dependence structure is now well understood, and scheduling techniques have been developed to exploit this shallow dependence structure for efficient parallel implementations. A related, applied research strand has studied methods by which certain iterative task-based algorithms can be efficiently parallelized via relaxed concurrent priority schedulers. These allow for high concurrency when inserting and removing tasks, at the cost of executing superfluous work due to the relaxed semantics of the scheduler. In this work, we take a step towards unifying these two research directions, by showing that there exists a family of relaxed priority schedulers that can efficiently and deterministically execute classic iterative algorithms such as greedy maximal independent set (MIS) and matching. Our primary result shows that, given a randomized scheduler with an expected relaxation factor of $k$ in terms of the maximum allowed priority inversions on a task, and any graph on $n$ vertices, the scheduler is able to execute greedy MIS with only an additive factor of poly($k$) expected additional iterations compared to an exact (but not scalable) scheduler. This counter-intuitive result demonstrates that the overhead of relaxation when computing MIS is not dependent on the input size or structure of the input graph. Experimental results show that this overhead can be clearly offset by the gain in performance due to the highly scalable scheduler. In sum, we present an efficient method to deterministically parallelize iterative sequential algorithms, with provable runtime guarantees in terms of the number of executed tasks to completion.Comment: PODC 2018, pages 377-386 in proceeding

Whole family-based physical activity promotion intervention: the Families Reporting Every Step to Health pilot randomised controlled trial protocol

Introduction : Family-based physical activity (PA) interventions present a promising avenue to promote children’s activity, however, high-quality experimental research is lacking. This paper describes the protocol for the FRESH (Families Reporting Every Step to Health) pilot trial, a child-led family-based PA intervention delivered online.  Methods and analysis : FRESH is a three-armed, parallel-group, randomised controlled pilot trial using a 1:1:1 allocation ratio with follow-up assessments at 8- and 52-weeks post-baseline. Families will be eligible if a minimum of one child in school Years 3-6 (aged 7-11 years) and at least one adult responsible for that child are willing to participate. Family members can take part in the intervention irrespective of their participation in the accompanying evaluation and vice versa. Following baseline assessment, families will be randomly allocated to one of three arms: (1) FRESH, (2) pedometer-only, or (3) no-intervention control. All family members in the pedometer-only and FRESH arms receive pedometers and generic PA promotion information. FRESH families additionally receive access to the intervention website; allowing participants to select step challenges to ‘travel’ to target cities around the world, log steps, and track progress as they virtually globetrot. Control families will receive no treatment. All family members will be eligible to participate in the evaluation with two follow-ups (8 and 52 weeks). Physical (e.g., fitness, blood pressure), psychosocial (e.g., social support), and behavioural (e.g., objectively-measured family PA) measures will be collected each time point. At 8-week follow-up, a mixed-methods process evaluation will be conducted (questionnaires and family focus groups) assessing acceptability of the intervention and evaluation. FRESH families’ website engagement will also be explored.  Ethics and dissemination : This study received ethical approval from the Ethics Committee for the School of the Humanities and Social Sciences at the University of Cambridge. Findings will be disseminated via peer-reviewed publications, conferences, and to participating families

A biomechanical analysis of the heavy sprint-style sled pull and comparison with the back squat

This study compared the biomechanical characteristics of the heavy sprint-style sled pull and squat. Six experienced male strongman athletes performed sled pulls and squats at 70% of their 1RM squat. Significant kinematic and kinetic differences were observed between the sled pull start and squat at the start of the concentric phase and at maximum knee extension. The first stride of the heavy sled pull demonstrated significantly (