DSFNet: Convolutional Encoder-Decoder Architecture Combined Dual-GCN and Stand-alone Self-attention by Fast Normalized Fusion for Polyps Segmentation

In the past few decades, deep learning technology has been widely used in medical image segmentation and has made significant breakthroughs in the fields of liver and liver tumor segmentation, brain and brain tumor segmentation, video disc segmentation, heart image segmentation, and so on. However, the segmentation of polyps is still a challenging task since the surface of the polyps is flat and the color is very similar to that of surrounding tissues. Thus, It leads to the problems of the unclear boundary between polyps and surrounding mucosa, local overexposure, and bright spot reflection. To counter this problem, this paper presents a novel U-shaped network, namely DSFNet, which effectively combines the advantages of Dual-GCN and self-attention mechanisms. First, we introduce a feature enhancement block module based on Dual-GCN module as an attention mechanism to enhance the feature extraction of local spatial and structural information with fine granularity. Second, the stand-alone self-attention module is designed to enhance the integration ability of the decoding stage model to global information. Finally, the Fast Normalized Fusion method with trainable weights is used to efficiently fuse the corresponding three feature graphs in encoding, bottleneck, and decoding blocks, thus promoting information transmission and reducing the semantic gap between encoder and decoder. Our model is tested on two public datasets including Endoscene and Kvasir-SEG and compared with other state-of-the-art models. Experimental results show that the proposed model surpasses other competitors in many indicators, such as Dice, MAE, and IoU. In the meantime, ablation studies are also conducted to verify the efficacy and effectiveness of each module. Qualitative and quantitative analysis indicates that the proposed model has great clinical significance.Comment: 10 pages, 6 figures, 3 table

Polar Solvent-Induced Unprecedented Supergelation of (Un)Weathered Crude Oils at Room Temperature

Use of carrier solvents to assist dissolution of phase-selective organogelators (PSOGs) before application in oil gelation is a common approach for solution-based gelators. Because of the competition in H-bonds by the polar carrier solvent, decreased gelling ability of PSOGs was often observed. That is, while data are available, the previously documented biphasic minimum gelling concentrations (BMGCs) are much larger than the MGCs determined using heating–cooling cycle for the same PSOG against the same oil. In this study, we show that, by minimizing amount of polar carrier solvent used, the gelling ability of PSOGs actually can be enhanced very substantially, rather than being weakened. More specifically, we demonstrate that use of a minute amount of polar carrier solvents of different types (e.g., ethyl acetate, acetone, acetonitrile, and tetrahydrofuran) significantly enhances the gelling ability of seven structurally different organogelators in hydrophobic oil. In particular, with the use of 5 vol % essentially nontoxic ethyl acetate, application of this previously unexplored strategy onto four monopeptide-based PSOGs produces up to 11-fold improvement in biphasic gelling ability toward seven (un)­weathered crude oils of widely ranging viscosities. While collectively overcoming many problematic issues (slow gelling action, low gelling ability, or a need to use hot or toxic solvent for dissolution of gelator) associated with PSOGs, this surprisingly simple yet powerful and reliable method produces unprecedented rapid supergelation of crude oil at room temperature, with BMGCs of as low as 0.38 w/v % (e.g., 3.8 g per liter of crude oil) and an averaged reduction in material cost of gelators by 85–97%

Impact of High Lipoprotein(a) on Long‐Term Survival Following Coronary Artery Bypass Grafting

Background Lipoprotein(a) is a possible causal risk factor for atherosclerosis and related complications. The distribution and prognostic implication of lipoprotein(a) in patients undergoing coronary artery bypass grafting remain unknown. This study aimed to assess the impact of high lipoprotein(a) on the long‐term prognosis of patients undergoing coronary artery bypass grafting. Methods and Results Consecutive patients with stable coronary artery disease who underwent isolated coronary artery bypass grafting from January 2013 to December 2018 from a single‐center cohort were included. The primary outcome was all‐cause death. The secondary outcome was a composite of major adverse cardiovascular and cerebrovascular events. Of the 18 544 patients, 4072 (22.0%) were identified as the high‐lipoprotein(a) group (≥50 mg/dL). During a median follow‐up of 3.2 years, primary outcomes occurred in 587 patients. High lipoprotein(a) was associated with increased risk of all‐cause death (high lipoprotein(a) versus low lipoprotein(a): adjusted hazard ratio [aHR], 1.31 [95% CI, 1.09–1.59]; P=0.005; lipoprotein(a) per 1‐mg/dL increase: aHR, 1.003 [95% CI, 1.001–1.006]; P=0.011) and major adverse cardiovascular and cerebrovascular events (high lipoprotein(a) versus low lipoprotein(a): aHR, 1.18 [95% CI, 1.06–1.33]; P=0.004; lipoprotein(a) per 1‐mg/dL increase: aHR, 1.002 [95% CI, 1.001–1.004]; P=0.002). The lipoprotein(a)‐related risk was greater in patients with European System for Cardiac Operative Risk Evaluation <3, and tended to attenuate in patients receiving arterial grafts. Conclusions More than 1 in 5 patients with stable coronary artery disease who underwent coronary artery bypass grafting were exposed to high lipoprotein(a), which is associated with higher risks of death and major adverse cardiovascular and cerebrovascular events. The adverse effects of lipoprotein(a) were more pronounced in patients with clinically low‐risk profiles or not receiving arterial grafts

CEPC Technical Design Report -- Accelerator

International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

CEPC Technical Design Report -- Accelerator

International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

CEPC Technical Design Report -- Accelerator

The Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

CEPC Technical Design Report -- Accelerator

International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s