Translation and cultural adaptation of the questionnaire on the reason for food choices (Food Choice Questionnaire - FCQ) into Portuguese

The Food Choice Questionnaire (FCQ) assesses the importance that subjects attribute to nine factors related to food choices: health, mood, convenience, sensory appeal, natural content, price, weight control, familiarity and ethical concern. This study sought to assess the applicability of the FCQ in Brazil; it describes the translation and cultural adaptation from English into Portuguese of the FCQ via the following steps: independent translations, consensus, back-translation, evaluation by a committee of experts, semantic validation and pre-test. The pre-test was run with a randomly sampled group of 86 male and female college students from different courses with a median age of 19. Slight differences between the versions were observed and adjustments were made. After minor changes in the translation process, the committee of experts considered that the Brazilian Portuguese version was semantically and conceptually equivalent to the English original. Semantic validation showed that the questionnaire is easily understood. The instrument presented a high degree of internal consistency. The study is the first stage in the process of validating an instrument, which consists of face and content validity. Further stages, already underway, are needed before other researchers can use it.O Food Choice Questionnaire (FCQ) avalia a importância atribuída pelos indivíduos a nove fatores relacionados às escolhas alimentares: saúde, humor, conveniência, apelo sensorial, conteúdo natural, preço, controle de peso, familiaridade e preocupação ética. O estudo objetivou descrever o processo de tradução e adaptação cultural do FCQ para a língua portuguesa e avaliar sua aplicabilidade com as seguintes etapas: traduções independentes, obtenção do consenso em português, retrotradução, avaliação por um comitê de especialistas, validação semântica e pré-teste. Este foi aplicado em uma amostra aleatória de 86 estudantes universitários, de ambos os sexos, mediana de 19 anos de idade. Pequenas diferenças entre as versões foram observadas e poucas adaptações realizadas. Após discretas modificações nos processos de tradução, o comitê de especialistas considerou que a versão para o português apresentou equivalências semântica e conceitual. A validação semântica demonstrou fácil compreensão. O instrumento apresentou alto grau de consistência interna. O estudo foi a primeira etapa do processo de validação de um instrumento, que é a validade de face e de conteúdo. Novas etapas, que já se encontram em andamento, são necessárias antes de sua utilização por outros pesquisadores

Efeitos das emissões de cana de açúcar sobre as vias respiratórias

A utilização da cana-de-açúcar e , consequentemente, do etanol como meio combustível é visto por muitos críticos como “ecologicamente correto”. No entanto, a queima dessa biomassa traz diversas consequências tanto para o meio ambiente quanto para os seres vivos, incluindo a poluição da água e da vegetação, o arrefecimento da diversidade biológica, a contaminação de ecossistemas vizinhos, as condições de trabalho degradantes dos camponeses, sendo eles expostos a riscos físicos, químicos e biológicos principalmente que acometem também a população próxima. Nesse sentido, são vistos vários efeitos prejudiciais ao sistema respiratório, os quais esse artigo busca abordar, como os quadros de inflamação e fibrose pulmonar com o objetivo de apontar o mito da energia limpa do agrocombustível e de estimular a pesquisa de formas realmente sustentáveis de energia

Implicações Cardiovasculares na Covid-19: Uma Revisão Sistemática / Cardiovascular Implications in Covid-19: A Systematic Review

INTRODUÇÃO: A infecção pelo SARS-CoV-2 tem sido associada à múltiplas repercussões clínicas, descritas em diversos órgãos e sistemas. A associação entre a COVID-19 e o acometimento do sistema cardiovascular ainda é pouco documentada, bem como as suas possíveis consequências. METODOLOGIA: Foi conduzida uma revisão sistemática da literatura. As buscas foram realizadas no mês de agosto de 2020, na base de dados National Library of Medicine (MEDLINE). Os descritores utilizados foram: "COVID-19" [Supplementary Concept] e "Cardiovascular Diseases"[Mesh]. Inicialmente foram encontrados 70 artigos e, após a análise dos resumos e da aplicação dos critérios de inclusão e exclusão, 25 artigos foram selecionados. Foi realizada a busca continuada nas referências dos artigos encontrados, resultando em um escopo final de 27 artigos. Por fim, os estudos foram submetidos à análise quantitativa e qualitativa, resultando em 20 artigos que estão incluídos nesta revisão sistemática. A escala de sistematização PRISMA foi utilizada a fim de aprimorar os resultados desta revisão. RESULTADOS: Os estudos demonstraram que a ocorrência de manifestações cardiovasculares inclui complicações tromboembólicas, elevação dos marcadores cardíacos e afecção miocárdica. Entretanto, diversos estudos apresentam limitações como dificuldade na obtenção de dados, escassez de recursos e curto tempo de acompanhamento. CONCLUSÃO: Apesar dos resultados encontrados e das evidências disponíveis, a condução de novos estudos ainda é necessária para esclarecer o envolvimento cardiovascular na COVID-19

USE OF ATHEROGENIC INDICES AS ASSESSMENT METHODS FOR CLINICAL ATHEROSCLEROTIC DISEASES

Accurate assessment of clinical atherosclerotic diseases is essential to guide effective therapeutic interventions, and atherogenic indices have emerged as valuable methods in this setting. The complexity of these pathologies demands approaches that go beyond the simple measurement of total cholesterol, requiring tools that consider the interaction between different lipoproteins and other risk factors. In this context, the use of atherogenic indices appears as a promising approach, providing a more comprehensive and refined assessment of atherosclerotic conditions. Objective: To comprehensively analyze scientific studies published in the last 10 years that investigated the use of atherogenic indices as methods of evaluating clinical atherosclerotic diseases. The review seeks to consolidate the available evidence by examining the effectiveness of these indices in early identification, risk stratification and monitoring the progress of atherosclerotic diseases. Methodology: The systematic review was conducted following the PRISMA guidelines. The PubMed, Scielo and Web of Science databases were consulted to identify relevant studies published in the last 10 years. The descriptors used were "atherogenic indices", "atherosclerotic diseases", "clinical assessment", "lipoproteins" and "cardiovascular risk factors". Inclusion criteria considered original studies that investigated the use of atherogenic indices in clinical populations, while exclusion criteria involved studies with unrepresentative samples and inadequate atherosclerotic assessment methods. Results: The results of the review highlight the diversity of available atherogenic indices and their usefulness in evaluating different aspects of atherosclerotic diseases, including prediction of cardiovascular events, risk stratification and treatment monitoring. The analysis identified indices that proved to be particularly sensitive and specific in different clinical contexts. Conclusion: In summary, the systematic review highlights the relevance of atherogenic indices as valuable tools in the assessment of clinical atherosclerotic diseases. The diversity of these indices and their ability to provide comprehensive information highlights their importance in clinical practice, contributing to a more refined and personalized approach to the management of these conditions.Accurate assessment of clinical atherosclerotic diseases is essential to guide effective therapeutic interventions, and atherogenic indices have emerged as valuable methods in this setting. The complexity of these pathologies demands approaches that go beyond the simple measurement of total cholesterol, requiring tools that consider the interaction between different lipoproteins and other risk factors. In this context, the use of atherogenic indices appears as a promising approach, providing a more comprehensive and refined assessment of atherosclerotic conditions. Objective: To comprehensively analyze scientific studies published in the last 10 years that investigated the use of atherogenic indices as methods of evaluating clinical atherosclerotic diseases. The review seeks to consolidate the available evidence by examining the effectiveness of these indices in early identification, risk stratification and monitoring the progress of atherosclerotic diseases. Methodology: The systematic review was conducted following the PRISMA guidelines. The PubMed, Scielo and Web of Science databases were consulted to identify relevant studies published in the last 10 years. The descriptors used were "atherogenic indices", "atherosclerotic diseases", "clinical assessment", "lipoproteins" and "cardiovascular risk factors". Inclusion criteria considered original studies that investigated the use of atherogenic indices in clinical populations, while exclusion criteria involved studies with unrepresentative samples and inadequate atherosclerotic assessment methods. Results: The results of the review highlight the diversity of available atherogenic indices and their usefulness in evaluating different aspects of atherosclerotic diseases, including prediction of cardiovascular events, risk stratification and treatment monitoring. The analysis identified indices that proved to be particularly sensitive and specific in different clinical contexts. Conclusion: In summary, the systematic review highlights the relevance of atherogenic indices as valuable tools in the assessment of clinical atherosclerotic diseases. The diversity of these indices and their ability to provide comprehensive information highlights their importance in clinical practice, contributing to a more refined and personalized approach to the management of these conditions

RISK FACTORS FOR OPERATIVE WOUND INFECTION IN PATIENTS UNDERGOING PEDIATRIC CARDIAC SURGERY

  Surgical wound infection is a significant complication in patients undergoing pediatric cardiac surgery, which can compromise the postoperative recovery process and increase morbidity. Several risk factors are associated with this condition, including patient characteristics, type of surgical procedure, hospital environment, and postoperative care practices. Understanding these factors is crucial to developing effective prevention strategies and optimizing clinical outcomes in this vulnerable population. Objective: To analyze and synthesize the available evidence on the risk factors for surgical wound infection in patients undergoing pediatric cardiac surgery. The aim is to identify patterns and gaps in the literature, contributing to a more comprehensive understanding of the elements that influence the occurrence of this specific complication. Methodology: The review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Scielo and Web of Science databases were consulted to identify studies published in the last 10 years, using the descriptors "pediatric heart surgery", "operative wound infection", "risk factors", "children" and "prevention ". Three inclusion criteria were established, considering original studies that addressed risk factors in pediatric cardiac surgery, while three exclusion criteria were applied to filter articles that did not meet the specific objectives of the review. Results: Results revealed a variety of risk factors, including patient age, length of surgery, presence of comorbidities, and infection control practices. The review highlighted the importance of specific preventive strategies for the pediatric population undergoing cardiac procedures. Conclusion: This systematic review provides a comprehensive overview of risk factors for surgical wound infection in pediatric cardiac surgery, emphasizing the need for personalized prevention approaches. The conclusions highlight the importance of targeting preventive interventions, adapting them to the unique characteristics of this population, aiming to improve clinical results and reduce the incidence of postoperative infections.  Surgical wound infection is a significant complication in patients undergoing pediatric cardiac surgery, which can compromise the postoperative recovery process and increase morbidity. Several risk factors are associated with this condition, including patient characteristics, type of surgical procedure, hospital environment, and postoperative care practices. Understanding these factors is crucial to developing effective prevention strategies and optimizing clinical outcomes in this vulnerable population. Objective: To analyze and synthesize the available evidence on the risk factors for surgical wound infection in patients undergoing pediatric cardiac surgery. The aim is to identify patterns and gaps in the literature, contributing to a more comprehensive understanding of the elements that influence the occurrence of this specific complication. Methodology: The review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Scielo and Web of Science databases were consulted to identify studies published in the last 10 years, using the descriptors "pediatric heart surgery", "operative wound infection", "risk factors", "children" and "prevention ". Three inclusion criteria were established, considering original studies that addressed risk factors in pediatric cardiac surgery, while three exclusion criteria were applied to filter articles that did not meet the specific objectives of the review. Results: Results revealed a variety of risk factors, including patient age, length of surgery, presence of comorbidities, and infection control practices. The review highlighted the importance of specific preventive strategies for the pediatric population undergoing cardiac procedures. Conclusion: This systematic review provides a comprehensive overview of risk factors for surgical wound infection in pediatric cardiac surgery, emphasizing the need for personalized prevention approaches. The conclusions highlight the importance of targeting preventive interventions, adapting them to the unique characteristics of this population, aiming to improve clinical results and reduce the incidence of postoperative infections

Avanços no Entendimento do Desenvolvimento Infantil em Crianças com Transtorno do Espectro Autista (TEA): Implicações Clínicas e Terapêuticas.

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that affects social communication and involves repetitive or restrictive behaviors. With its increasing prevalence, the need to understand and effectively intervene in ASD is urgent. This review focuses on recent advancements related to understanding child development in children with ASD and the subsequent clinical and therapeutic implications. Behavioral interventions continue to be the cornerstone of treatment, with intensive and well-structured approaches showing improvements in areas such as communication and social skills. However, play-based therapies have gained prominence, providing natural environments for social development. Simultaneously, the field of pharmacological interventions has evolved, aiming to address specific symptoms and associated comorbidities of ASD. Despite promising individualized approaches, combining multiple interventions proves to be more effective, considering the multifaceted nature of ASD. Future research should continue to focus on evidence-based and individualized treatments, with an emphasis on a deep understanding of the underlying neurobiological mechanisms and long-term assessment of interventions.O Transtorno do Espectro Autista (TEA) é uma condição neurodesenvolvimental que afeta a comunicação social e comportamentos repetitivos ou restritos. Com uma prevalência crescente, a necessidade de entender e intervir de forma eficaz no TEA é urgente. Esta revisão foca nos avanços recentes relacionados ao entendimento do desenvolvimento infantil em crianças com TEA e as subsequentes implicações clínicas e terapêuticas. Intervenções comportamentais continuam a ser a espinha dorsal do tratamento, com abordagens intensivas e bem-estruturadas demonstrando melhorias em áreas como comunicação e habilidades sociais. No entanto, terapias baseadas em jogo têm ganhado destaque, proporcionando ambientes naturais para desenvolvimento social. Paralelamente, o campo das intervenções farmacológicas tem evoluído, visando tratar sintomas específicos e comorbidades associadas ao TEA. Apesar das promissoras abordagens individualizadas, combinar múltiplas intervenções se mostra mais eficaz, considerando a natureza multifacetada do TEA. As pesquisas futuras devem continuar focando em tratamentos individualizados e baseados em evidências, com ênfase em uma compreensão profunda dos mecanismos neurobiológicos subjacentes e avaliação de longo prazo das intervenções

Mapping density, diversity and species-richness of the Amazon tree flora

Using 2.046 botanically-inventoried tree plots across the largest tropical forest on Earth, we mapped tree species-diversity and tree species-richness at 0.1-degree resolution, and investigated drivers for diversity and richness. Using only location, stratified by forest type, as predictor, our spatial model, to the best of our knowledge, provides the most accurate map of tree diversity in Amazonia to date, explaining approximately 70% of the tree diversity and species-richness. Large soil-forest combinations determine a significant percentage of the variation in tree species-richness and tree alpha-diversity in Amazonian forest-plots. We suggest that the size and fragmentation of these systems drive their large-scale diversity patterns and hence local diversity. A model not using location but cumulative water deficit, tree density, and temperature seasonality explains 47% of the tree species-richness in the terra-firme forest in Amazonia. Over large areas across Amazonia, residuals of this relationship are small and poorly spatially structured, suggesting that much of the residual variation may be local. The Guyana Shield area has consistently negative residuals, showing that this area has lower tree species-richness than expected by our models. We provide extensive plot meta-data, including tree density, tree alpha-diversity and tree species-richness results and gridded maps at 0.1-degree resolution

Geography and ecology shape the phylogenetic composition of Amazonian tree communities

AimAmazonia hosts more tree species from numerous evolutionary lineages, both young and ancient, than any other biogeographic region. Previous studies have shown that tree lineages colonized multiple edaphic environments and dispersed widely across Amazonia, leading to a hypothesis, which we test, that lineages should not be strongly associated with either geographic regions or edaphic forest types.LocationAmazonia.TaxonAngiosperms (Magnoliids; Monocots; Eudicots).MethodsData for the abundance of 5082 tree species in 1989 plots were combined with a mega-phylogeny. We applied evolutionary ordination to assess how phylogenetic composition varies across Amazonia. We used variation partitioning and Moran's eigenvector maps (MEM) to test and quantify the separate and joint contributions of spatial and environmental variables to explain the phylogenetic composition of plots. We tested the indicator value of lineages for geographic regions and edaphic forest types and mapped associations onto the phylogeny.ResultsIn the terra firme and várzea forest types, the phylogenetic composition varies by geographic region, but the igapó and white-sand forest types retain a unique evolutionary signature regardless of region. Overall, we find that soil chemistry, climate and topography explain 24% of the variation in phylogenetic composition, with 79% of that variation being spatially structured (R2 = 19% overall for combined spatial/environmental effects). The phylogenetic composition also shows substantial spatial patterns not related to the environmental variables we quantified (R2 = 28%). A greater number of lineages were significant indicators of geographic regions than forest types.Main ConclusionNumerous tree lineages, including some ancient ones (>66 Ma), show strong associations with geographic regions and edaphic forest types of Amazonia. This shows that specialization in specific edaphic environments has played a long-standing role in the evolutionary assembly of Amazonian forests. Furthermore, many lineages, even those that have dispersed across Amazonia, dominate within a specific region, likely because of phylogenetically conserved niches for environmental conditions that are prevalent within regions

Geography and ecology shape the phylogenetic composition of Amazonian tree communities

Aim: Amazonia hosts more tree species from numerous evolutionary lineages, both young and ancient, than any other biogeographic region. Previous studies have shown that tree lineages colonized multiple edaphic environments and dispersed widely across Amazonia, leading to a hypothesis, which we test, that lineages should not be strongly associated with either geographic regions or edaphic forest types. Location: Amazonia. Taxon: Angiosperms (Magnoliids; Monocots; Eudicots). Methods: Data for the abundance of 5082 tree species in 1989 plots were combined with a mega-phylogeny. We applied evolutionary ordination to assess how phylogenetic composition varies across Amazonia. We used variation partitioning and Moran\u27s eigenvector maps (MEM) to test and quantify the separate and joint contributions of spatial and environmental variables to explain the phylogenetic composition of plots. We tested the indicator value of lineages for geographic regions and edaphic forest types and mapped associations onto the phylogeny. Results: In the terra firme and várzea forest types, the phylogenetic composition varies by geographic region, but the igapó and white-sand forest types retain a unique evolutionary signature regardless of region. Overall, we find that soil chemistry, climate and topography explain 24% of the variation in phylogenetic composition, with 79% of that variation being spatially structured (R$^{2}$ = 19% overall for combined spatial/environmental effects). The phylogenetic composition also shows substantial spatial patterns not related to the environmental variables we quantified (R$^{2}$ = 28%). A greater number of lineages were significant indicators of geographic regions than forest types. Main Conclusion: Numerous tree lineages, including some ancient ones (>66 Ma), show strong associations with geographic regions and edaphic forest types of Amazonia. This shows that specialization in specific edaphic environments has played a long-standing role in the evolutionary assembly of Amazonian forests. Furthermore, many lineages, even those that have dispersed across Amazonia, dominate within a specific region, likely because of phylogenetically conserved niches for environmental conditions that are prevalent within regions

A evolução clínica do paciente portador de abscesso pulmonar: Clinical evolution of patients with lung abscess

Atualmente, com a era da antibioticoterapia e demais meios terapêuticos, o abscesso pulmonar decaiu em termos de morbimortalidade, mas ainda permanece como um desafio em termos diagnósticos e manejo clínico. O abscesso pulmonar corresponde a uma cavidade com pus no pulmão, envolvido por tecido inflamado e geralmente oriunda de uma infecção. O artigo objetivou descrever de modo narrativo a evolução clínica do portador de abscesso pulmonar, ressaltando os principais dados para a compreensão deste fenômeno. Um abscesso pulmonar é causado principalmente por bactérias existentes na boca ou garganta, a qual são aspiradas até os pulmões. A sintomatologia é inespecífica, abordando fadiga, inapetência, sudorese noturna, febre, perda ponderal e tosse com expectoração. O quadro clínico geralmente necessita do complemento de exames de imagem, principalmente a radiografia torácica para diagnóstic