2,544 research outputs found
125 GeV Higgs as a pseudo-Goldstone boson in supersymmetry with vector-like matters
We propose a possibility of the 125 GeV Higgs being a pseudo-Goldstone boson
in supersymmetry with extra vector-like fermions. Higgs mass is obtained from
loops of top quark and vector-like fermions from the global symmetry breaking
scale f at around TeV. The mu, Bmu/mu \sim f are generated from the dynamics of
global symmetry breaking and the Higgs quartic coupling vanishes at f as tan
beta \simeq 1. The relation of msoft \sim with f \sim mu \sim m_soft
\sim TeV is obtained and large mu does not cause a fine tuning for the
electroweak symmetry breaking. The Higgs to di-photon rate can be enhanced from
the loop of uncolored vector-like matters. The stability problem of Higgs
potential with vector-like fermions can be nicely cured by the UV completion
with the Goldstone picture.Comment: 28 pages, 8 figure
Structural and Thermal Stabilities of LixCoO2 cathode for LIB studied by a temperature programmed reduction (TPR).
In recent years, research and development of battery technology has primarily been focused on the lithium-ion batteries (LIB) due to the high specific energy density, and therefore are widely utilized as the energy source for portable electronics and electric vehicles. However, the battery safety is an essential issue to overcome, as the battery are required higher power density and larger capacity. Many efforts have been conducted to improve the safety of LIB in the active material processing, as well as the cell battery manufacturing and management technology
CONTENTS
PURPOSE:Patients with combined pulmonary fibrosis and emphysema (CPFE) have been suggested to have an increased risk of lung cancer. We conducted a systematic review of all published data and performed a meta-analysis to define the characteristics of lung cancer that develops in CPFE. METHOD:We searched Pubmed, Embase, and Cochrane to find original articles about lung cancer and CPFE published prior to September 2015. All titles/abstracts were reviewed by two radiologists to identify articles that used predefined selection criteria. Summary estimates were generated using a random-effect model and odds ratios (ORs) to develop squamous cell carcinoma (SqCC) were calculated. Kaplan-Meier survival curves were obtained for the survival of patients with CPFE and non-CPFE. RESULTS:Nine original articles that assessed 620 patients were included in this review. In the pooled data, patients were older age (70.4 years), almost all were heavy smokers (53.5 pack years), and males were predominant (92.6%). SqCC was the most common type (42.3%), followed by adenocarcinoma (34.4%). Compared with lung cancer population with an otherwise normal lung, the OR to develop SqCC in CPFE was 9.06 (95% CI, 6.08-13.5). The ORs in CPFE compared with lung cancers that developed in lungs with fibrosis or emphysema were also higher. The median survival for CPFE patients with lung cancer (19.5 months) was significantly shorter than in non-CPFE (53.1 months). CONCLUSIONS:Lung cancer in CPFE, most commonly SqCC, presents in elderly heavy smokers with a male predominance. The median survival for CPFE patients with lung cancer is 19.5 months
Angiomyofibroblastoma-Like Tumor of the Scrotum
Various tumors can occur in the scrotum. Of them, angiomyofibroblastoma-like tumors are very rare mesenchymal tumors. Angiomyofibroblastoma-like tumors cannot be easily differentially diagnosed from other malignant tumors invading the male genital tract on the basis of clinical characteristics and imaging study. Therefore, surgical removal and a histopathologic diagnosis must also be performed
STAT1 and Nmi are downstream targets of Ets-1 transcription factor in MCF-7 human breast cancer cell
AbstractEts-1 is a cellular homologue of the product of the viral ets oncogene of the E26 virus, and it functions as a tissue-specific transcription factor. It plays an important role in cell proliferation, differentiation, lymphoid cell development, transformation, angiogenesis, and apoptosis. Ets-1 controls the expression of critical genes involved in these processes by binding to ets binding sites present in the transcriptional regulatory regions. Here, we transiently overexpressed Ets-1 in MCF-7 and comprehensively searched for potential downstream targets of Ets-1 by cDNA microarray analysis. The expressions of several interferon-related genes including STAT1 and Nmi were augmented by the overexpression of Ets-1. RT-PCR and Western blotting confirmed the increase in the levels of STAT1 and Nmi mRNA and protein. In contrast, Ets-1 siRNA decreased the expression of STAT1 and Nmi proteins. As in our transient transfection experiments, stable overexpression of Ets-1, also increased the protein expression of STAT1 and Nmi in MCF-7 cells. Taken together, our results indicate that STAT1 and Nmi are downstream targets of Ets-1 in MCF-7 human breast cancer cells
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