Remarkable macrolichens in the urban area of Aachen and the north-western Eifel Mountains

Es wird über Großflechtenfunde, speziell epiphytische Arten, aus dem Aachener Stadtgebiet und der nordwestlichen Eifel berichtet. Zu den folgenden Arten werden genauere Angaben zu Fundorten gemacht: Bryoria fuscescens, Flavoparmelia soredians, Hyperphyscia adglutinata, Hypotrachyna afrorevoluta, Hypotrachyna revoluta s. str., Melanohalea laciniatula (= Melanelia laciniatula), Parmelia submontana, Parmelina pastillifera, Physconia distorta, Physconia enteroxantha, Physconia perisidiosa, Punctelia borreri, Ramalina fastigiata, Sphaerophorus globosus, Tuckermanopsis chlorophylla (= Cetraria chlorophylla), Usnea dasypoga (= Usnea filipendula) und Xanthomendoza fallax (= Xanthoria fallax). Diese und weitere Arten werden anhand von Fotos dargestellt.The article reports on macrolichens, especially epiphytic species, from the urban area of Aachen and the northwestern Eifel Mountains. Localities of the following species are presented: Bryoria fuscescens, Flavoparmelia soredians, Hyperphyscia adglutinata, Hypotrachyna afrorevoluta, Hypotrachyna revoluta s. str., Melanohalea laciniatula (= Melanelia laciniatula), Parmelia submontana, Parmelina pastillifera, Physconia distorta, Physconia enteroxantha, Physconia perisidiosa, Punctelia borreri, Ramalina fastigiata, Sphaerophorus globosus, Tuckermanopsis chlorophylla (= Cetraria chlorophylla), Usnea dasypoga (= Usnea filipendula) and Xanthomendoza fallax (= Xanthoria fallax). These and further species are illustrated on the basis of pictures

Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera

The cotton bollworm, Helicoverpa armigera (Hübner) is one of the most serious insect pest species to evolve resistance against many insecticides from different chemical classes. This species has evolved resistance to the pyrethroid insecticides across its native range and is becoming a truly global pest after establishing in South America and having been recently recorded in North America. A chimeric cytochrome P450 gene, CYP337B3, has been identified as a resistance mechanism for resistance to fenvalerate and cypermethrin. Here we show that this resistance mechanism is common around the world with at least eight different alleles. It is present in South America and has probably introgressed into its closely related native sibling species, Helicoverpa zea. The different alleles of CYP337B3 are likely to have arisen independently in different geographic locations from selection on existing diversity. The alleles found in Brazil are those most commonly found in Asia, suggesting a potential origin for the incursion of H. armigera into the Americas.Additional co-authors: Mary E A Whitehouse, Pierre Jean Silvie, Sharon Downes, Lori Nemec, David G. Hecke

Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera

The cotton bollworm, Helicoverpa armigera (Hübner) is one of the most serious insect pest species to evolve resistance against many insecticides from different chemical classes. This species has evolved resistance to the pyrethroid insecticides across its native range and is becoming a truly global pest after establishing in South America and having been recently recorded in North America. A chimeric cytochrome P450 gene, CYP337B3, has been identified as a resistance mechanism for resistance to fenvalerate and cypermethrin. Here we show that this resistance mechanism is common around the world with at least eight different alleles. It is present in South America and has probably introgressed into its closely related native sibling species, Helicoverpa zea. The different alleles of CYP337B3 are likely to have arisen independently in different geographic locations from selection on existing diversity. The alleles found in Brazil are those most commonly found in Asia, suggesting a potential origin for the incursion of H. armigera into the Americas

Environmental Impact on Vascular Development Predicted by High-Throughput Screening

Background: Understanding health risks to embryonic development from exposure to environmental chemicals is a significant challenge given the diverse chemical landscape and paucity of data for most of these compounds. High-throughput screening (HTS) in the U.S. Environmental Protection Agency (EPA) ToxCast™ project provides vast data on an expanding chemical library currently consisting of > 1,000 unique compounds across > 500 in vitro assays in phase I (complete) and Phase II (under way). This public data set can be used to evaluate concentration-dependent effects on many diverse biological targets and build predictive models of prototypical toxicity pathways that can aid decision making for assessments of human developmental health and disease

Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera

The cotton bollworm, Helicoverpa armigera (Hübner) is one of the most serious insect pest species to evolve resistance against many insecticides from different chemical classes. This species has evolved resistance to the pyrethroid insecticides across its native range and is becoming a truly global pest after establishing in South America and having been recently recorded in North America. A chimeric cytochrome P450 gene, CYP337B3, has been identified as a resistance mechanism for resistance to fenvalerate and cypermethrin. Here we show that this resistance mechanism is common around the world with at least eight different alleles. It is present in South America and has probably introgressed into its closely related native sibling species, Helicoverpa zea. The different alleles of CYP337B3 are likely to have arisen independently in different geographic locations from selection on existing diversity. The alleles found in Brazil are those most commonly found in Asia, suggesting a potential origin for the incursion of H. armigera into the Americas.Financial support in Australia (to TKW) was provided by the Commonwealth Science and Industry Research Organisation, Land and Water, Health and Biosecurity, Agriculture. In Germany financial support (to DGH) was provided by the Max-Planck-Gesellschaft. NJ was supported by a grant from the Deutsche Forschungsgemeinschaf (DFG, Germany; JO 855/1-1)

Multiple recombination events between two cytochrome P450 loci contribute to global pyrethroid resistance in Helicoverpa armigera

The cotton bollworm, Helicoverpa armigera (Hubner) is one of the most serious insect pest species to evolve resistance against many insecticides from different chemical classes. This species has evolved resistance to the pyrethroid insecticides across its native range and is becoming a truly global pest after establishing in South America and having been recently recorded in North America. A chimeric cytochrome P450 gene, CYP337B3, has been identified as a resistance mechanism for resistance to fenvalerate and cypermethrin. Here we show that this resistance mechanism is common around the world with at least eight different alleles. It is present in South America and has probably introgressed into its closely related native sibling species, Helicoverpa zea. The different alleles of CYP337B3 are likely to have arisen independently in different geographic locations from selection on existing diversity. The alleles found in Brazil are those most commonly found in Asia, suggesting a potential origin for the incursion of H. armigera into the Americas

Uveal Melanoma - Standardised Procedure in Diagnosis, Therapy and Surveillance

Background Uveal melanoma is a rare intraocular tumour, for which there is currently no national evidence-based guideline in Germany. The aim of this project was to provide a common standard operating procedure (SOP) for the diagnosis, treatment and follow-up care of uveal melanoma, within the network of German leading oncology centres funded by German Cancer Aid. The SOP was created as part of a moderated consensus process. Results and Conclusion In a multistage process, a common SOP was developed for the diagnosis, therapy and follow-up of uveal melanoma, as based on current knowledge of the subject. Zusammenfassung Hintergrund Fur das uveale Melanom fehlt als seltene onkologische Erkrankung derzeit in Deutschland eine nationale evidenzbasierte Leitlinie. Bis diese erstellt wird, bietet sich eine zentrumsubergreifende Standard Operating Procedure (SOP) an. Ziel des Projektes war die Erarbeitung einer konsentierten SOP zur Diagnostik, Therapie und Nachsorge des uvealen Melanoms im Rahmen des Netzwerkes Onkologischer Spitzenzentren, die von der Deutschen Krebshilfe gefordert werden. Ergebnisse und Schlussfolgerung In einem auf dem aktuellen Wissensstand basierenden mehrstufigen Prozess eines moderierten Konsensusverfahrens konnte eine konsentierte SOP fur die Diagnostik, Therapie und Nachsorge des uvealen Melanoms erarbeitet werden

За кадры. 1954. № 15 (650)

Закончила свою работу IX студенческая научно-техническая конференция института / Н. Воробьев [и др.]За авангардную роль коммунистов в учебе / Н. Хлебников"Запросто" / Н. СибирскийАгитатор в группе / В. БукаевТревожные сигналы / Л. ГырылтуеваО так называемой "помощи" / А. Г. Бакиро