Integrating the green economy, circular economy and bioeconomy in a strategic sustainability framework

The green economy, circular economy and bioeconomy are popular narratives in macro-level sustainability discussions in policy, scientific research and business. These three narratives offer three different recipes to address economic, social and ecological goals, thus promoting different pathways for sustainability transformations. We employ the well-known Framework for Strategic Sustainable Development (The Natural Step Framework) to comparatively identify the relative and integrated contribution of the three narratives for global net sustainability. We conclude that none of the three narratives, individually, offer a comprehensive ‘package’ of solutions. However, when considered jointly as collaborative narratives, they point towards a society and economy based on renewable/reproductive and biodiversity-based/benign processes, delivering material and immaterial benefits that fulfil the economic and social requirements of all people now and in the future. While the complementary understanding of the circular economy, bioeconomy and green economy provides important guidelines for sustainability transformations post-Covid-19, there is a need for more holistic, systems-wide and integrative research work on potentially competing or supplementary sustainability narratives. This type of work of clarification and synthesis is relevant to a wide range of scholars and professionals, since the conceptual understanding of sustainability narratives informs practical implementation through strategies, actions and monitoring tools, in public and private decision-making.Peer reviewe

IP Mobility in Wireless Operator Networks

Wireless network access is gaining increased heterogeneity in terms of the types of IP capable access technologies. The access network heterogeneity is an outcome of incremental and evolutionary approach of building new infrastructure. The recent success of multi-radio terminals drives both building a new infrastructure and implicit deployment of heterogeneous access networks. Typically there is no economical reason to replace the existing infrastructure when building a new one. The gradual migration phase usually takes several years. IP-based mobility across different access networks may involve both horizontal and vertical handovers. Depending on the networking environment, the mobile terminal may be attached to the network through multiple access technologies. Consequently, the terminal may send and receive packets through multiple networks simultaneously. This dissertation addresses the introduction of IP Mobility paradigm into the existing mobile operator network infrastructure that have not originally been designed for multi-access and IP Mobility. We propose a model for the future wireless networking and roaming architecture that does not require revolutionary technology changes and can be deployed without unnecessary complexity. The model proposes a clear separation of operator roles: (i) access operator, (ii) service operator, and (iii) inter-connection and roaming provider. The separation allows each type of an operator to have their own development path and business models without artificial bindings with each other. We also propose minimum requirements for the new model. We present the state of the art of IP Mobility. We also present results of standardization efforts in IP-based wireless architectures. Finally, we present experimentation results of IP-level mobility in various wireless operator deployments.Erilaiset langattomat verkkoyhteydet lisääntyvät Internet-kykyisten teknologioiden muodossa. Lukuisten eri teknologioiden päällekkäinen käyttö johtuu vähitellen ja tarpeen mukaan rakennetusta verkkoinfrastruktuurista. Useita radioteknologioita (kuten WLAN, GSM ja UMTS) sisältävien päätelaitteiden (kuten älypuhelimet ja kannettavat tietokoneet) viimeaikainen kaupallinen menestys edesauttaa uuden verkkoinfrastruktuurin rakentamista, sekä mahdollisesti johtaa verkkoteknologioiden kirjon lisääntymiseen. Olemassa olevaa verkkoinfrastruktuuria ei kaupallisista syistä kannata korvata uudella teknologialla yhdellä kertaa, vaan vaiheittainen siirtymävaihe kestää tyypillisesti useita vuosia. Internet-kykyiset päätelaitteet voivat liikkua joko saman verkkoteknologian sisällä tai eri verkkoteknologioiden välillä. Verkkoympäristöstä riippuen liikkuvat päätelaitteet voivat liittyä verkkoon useiden verkkoyhteyksien kautta. Näin ollen päätelaite voi lähettää ja vastaanottaa tietoliikennepaketteja yhtäaikaisesti lukuisia verkkoja pitkin. Tämä väitöskirja käsittelee Internet-teknologioiden liikkuvuutta ja näiden teknologioiden tuomista olemassa oleviin langattomien verkko-operaattorien verkkoinfrastruktuureihin. Käsiteltäviä verkkoinfrastruktuureita ei alun perin ole suunniteltu Internet-teknologian liikkuvuuden ja monien yhtäaikaisten yhteyksien ehdoilla. Tässä työssä ehdotetaan tulevaisuuden langattomien verkkojen arkkitehtuurimallia ja ratkaisuja verkkovierailujen toteuttamiseksi. Ehdotettu arkkitehtuuri voidaan toteuttaa ilman mittavia teknologisia mullistuksia. Mallin mukaisessa ehdotuksessa verkko-operaattorin roolit jaetaan selkeästi (i) verkko-operaattoriin, (ii) palveluoperaattoriin ja (iii) yhteys- sekä verkkovierailuoperaattoriin. Roolijako mahdollistaa sen, että kukin operaattorityyppi voi kehittyä itsenäisesti, ja että teennäiset verkkoteknologiasidonnaisuudet poistuvat palveluiden tuottamisessa. Työssä esitetään myös alustava vaatimuslista ehdotetulle mallille, esimerkiksi yhteysoperaattorien laatuvaatimukset. Väitöskirja esittelee myös liikkuvien Internet-teknologioiden viimeisimmän kehityksen. Työssä näytetään lisäksi standardointituloksia Internet-kykyisissä langattomissa arkkitehtuureissa

COVID-19 Mitigation and Global Justice: On the Swedish Experiment

The novel coronavirus (from here on COVID-19) is an example of the many acute threats that the global society is creating to the sustainability of animal, ecosystem and human health as well as to global justice including economically sustainable development. COVID-19 is relatively unknown to natural science. The virus and its mitigation operate at the interface of various scientific disciplines (e.g. medicine), social sciences (e.g. strategic planning) and societal development (e.g. sustainability). COVID-19 also requires diverse stakeholders to take responsibility for the situation, political ideology inspired activism and an effort to achieve a truly global, not only Western solution, to the crisis. The objective of this paper is to argue that the human rights basis and the basic pillars of the “Swedish Experiment’s” approach to COVID-19 mitigation of the pandemic constitute a promising pathway for co-learning in the adaptation to the COVID-19 era. The authors find four pillars in the Swedish Experiment: 1) Natural Science, 2) Social Science, 3) Political Ideology and 4) Their mutually amplifying feed-back loops.</p

Regulation of excitation-contraction coupling in mouse cardiac myocytes: integrative analysis with mathematical modelling

<p>Abstract</p> <p>Background</p> <p>The cardiomyocyte is a prime example of inherently complex biological system with inter- and cross-connected feedback loops in signalling, forming the basic properties of intracellular homeostasis. Functional properties of cells and tissues have been studied e.g. with powerful tools of genetic engineering, combined with extensive experimentation. While this approach provides accurate information about the physiology at the endpoint, complementary methods, such as mathematical modelling, can provide more detailed information about the processes that have lead to the endpoint phenotype.</p> <p>Results</p> <p>In order to gain novel mechanistic information of the excitation-contraction coupling in normal myocytes and to analyze sophisticated genetically engineered heart models, we have built a mathematical model of a mouse ventricular myocyte. In addition to the fundamental components of membrane excitation, calcium signalling and contraction, our integrated model includes the calcium-calmodulin-dependent enzyme cascade and the regulation it imposes on the proteins involved in excitation-contraction coupling. With the model, we investigate the effects of three genetic modifications that interfere with calcium signalling: 1) ablation of phospholamban, 2) disruption of the regulation of L-type calcium channels by calcium-calmodulin-dependent kinase II (CaMK) and 3) overexpression of CaMK. We show that the key features of the experimental phenotypes involve physiological compensatory and autoregulatory mechanisms that bring the system to a state closer to the original wild-type phenotype in all transgenic models. A drastic phenotype was found when the genetic modification disrupts the regulatory signalling system itself, i.e. the CaMK overexpression model.</p> <p>Conclusion</p> <p>The novel features of the presented cardiomyocyte model enable accurate description of excitation-contraction coupling. The model is thus an applicable tool for further studies of both normal and defective cellular physiology. We propose that integrative modelling as in the present work is a valuable complement to experiments in understanding the causality within complex biological systems such as cardiac myocytes.</p

Tromboelastometria kliinisessä työssä

English summar