Psychometric evaluation of social phobia and anxiety inventory for children (SPAI-C) and social anxiety scale for children-revised (SASC-R)

The study evaluated the psychometric properties of Finnish versions of the Social Phobia and Anxiety Inventory for Children (SPAI-C) and the Social Anxiety Scale for Children-Revised (SASC-R). 352 students (M = 12.2 years) participated in the study and completed the SPAI-C and SASC-R. In addition, 68 participants (M = 12.2 years) and their parents were interviewed with the Schedule for Affective Disorders and Schizophrenia for School Aged Children (K-SADS-PL). The SPAI-C was more sensitive for identifying youth meeting criteria for social phobia (SP), whereas the SASC-R demonstrated greater specificity. The youth in this sample had lower mean total scores on the self-report questionnaires than did those in the original validitation studies of the SPAI-C and SASC-R conducted in America. These findings question whether cross-cultural differences in the expression of SP influence the clinical cut-off scores used in translated versions of social anxiety questionnaires

When does the Autism Spectrum Screening Questionnaire (ASSQ) predict autism spectrum disorders in primary school-aged children?

The aims of this study were, firstly, to study the association between parents’ and teachers’ ratings for the Finnish version of the Autism Spectrum Screening Questionnaire (ASSQ), secondly, to find out whether the original cut-off scores of the ASSQ identify primary school-aged children with Asperger syndrome (AS) or autism by using the Finnish ASSQ, and thirdly, to evaluate the validity of the ASSQ. Parents and/or teachers of higher-functioning (full-scale intelligence quotient ≥ 50) 8-year-old total population school children (n = 4,408) and 7–12-year-old outpatients with AS/autism (n = 47) completed the Finnish version of the ASSQ. Agreement between informants was slight. In the whole total population, low positive correlation was found between parents’ and teachers’ ratings, while in the sample of high-scoring children the correlation turned out to be negative. A cut-off of 30 for parents’ and teacher's summed score and 22 for teachers’ single score is recommended. A valid cut-off for parents’ single score could not been estimated. The clinicians are reminded that the ASSQ is a screening instrument, not a diagnosing instrument. The importance of using both parents’ and teachers’ ratings for screening in clinical settings is underlined

Familiality of Quantitative Autism Traits

Autistic traits exist along a continuum that extends into social functioning in the general population, and they aggregate in the family members of children with autism spectrum disorder (ASD). Quantitative measures are therefore essential when investigating the patterns of familiality of these traits. Prior studies have suggested differential inheritance patterns of autistic traits that depend on the cognitive level of the child with ASD as well as the family type.Our goal was to examine the family patterns of quantitative autism traits (QAT) in a group of simplex autism families of high-functioning children with ASD.We used the Social Responsiveness Scale (SRS) to evaluate QAT in 47 ASD families and 46 control families. SRS assessments (parental/spousal evaluations) were collected for the children with ASD, their siblings, and their parents as well as for the control children and their parents.The SRS was able to distinguish individuals with ASD from the control children and from their unaffected siblings. Significant group differences were also found when comparing the fathers of ASD families to control fathers and when comparing the brothers of individuals with ASD to control boys, with male members of ASD families having higher SRS scores. Gender differences were observed in the group of siblings of children with ASD and the group of parents of children with ASD, with males having higher scores than females. In ASD families, a positive trend between child and father QAT was found, whereas mothers' scores were not associated with child outcomes. By contrast, in control families, mothers' QAT correlated more strongly with child QAT.Autistic traits aggregate in the fathers and brothers of children with ASD in simplex autism families. The QAT levels of the family members should be taken into consideration when planning the rehabilitation of the child or adolescent with ASD and when designing family interventions

Psychometric evaluation of social phobia and anxiety inventory for children (SPAI-C) and social anxiety scale for children-revised (SASC-R)

International audienceThe study evaluated the psychometric properties of Finnish versions of the Social Phobia and Anxiety Inventory for Children (SPAI-C) and the Social Anxiety Scale for Children-Revised (SASC-R). 352 students (M = 12.2 years) participated in the study and completed the SPAI-C and SASC-R. In addition, 68 participants (M = 12.2 years) and their parents were interviewed with the Schedule for Affective Disorders and Schizophrenia for School Aged Children (K-SADS-PL). The SPAI-C was more sensitive for identifying youth meeting criteria for social phobia (SP), whereas the SASC-R demonstrated greater specificity. The youth in this sample had lower mean total scores on the self-report questionnaires than did those in the original validitation studies of the SPAI-C and SASC-R conducted in America. These findings question whether cross-cultural differences in the expression of SP influence the clinical cut-off scores used in translated versions of social anxiety questionnaires

Autismikirjon osamäärä (AQ) autismikirjon piirteitä seulomassa:seulontalomakkeen erottelukyky nuorilla aikuisilla

Abstrakti Autismikirjon piirteet ulottuvat sosiaalisten taitojen, kommunikaation, mielikuvituksen, tarkkaavuuden siirtämisen ja yksityiskohtien huomioimisen alueille. Näillä osa-alueilla esiintyviä piirteitä voidaan seuloa autismikirjon osamäärän (engl. autism spectrum quotient, AQ) avulla. Tämän tutkimuksen tavoitteena on saada suomalaiset viitearvot AQ:lle sekä tarkastella, erotteleeko AQ-lomake suomalaisia autismikirjon nuoria aikuisia oman sukupuolen nuorista aikuisista, joilla ei ole autismikirjon diagnoosia. Lisäksi tarkastellaan ryhmien suoriutumisessa olevia eroja osioittain sekä AQ:n sisäistä yhtenäisyyttä. Tutkimukseen osallistui 52 autismikirjon nuorta aikuista (39 miestä ja 13 naista) sekä 1686 verrokkia (577 miestä ja 1109 naista). Tulokset osoittavat, että autismikirjon henkilöiden pistemäärät nousevat samaa sukupuolta olevien verrokkihenkilöiden pistemääriä korkeammalle. AQ erottelee autismikirjon miehet melko hyvin verrokkimiehistä, mutta autismikirjon naiset vain kohtalaisesti verrokkinaisista. Osioanalyysissä eniten ryhmien välisiä tilastollisesti merkitseviä eroja tuli esille sosiaalisia taitoja ja kommunikaatiota mittaavissa väittämissä.Abstract Autism spectrum quotient (AQ) in screening features of autism spectrum : discriminatory ability of screening form in young adults Features of autism spectrum include areas of social skills, communication, imagination, attention switching and attention to details. These features can be screened with Autism Spectrum Quotient (AQ). The purpose of this study is to obtain Finnish performance values for AQ and to study whether the AQ discriminates Finnish young adults on the autism spectrum from same-gender controls without autism spectrum diagnosis. In addition, differences between groups in each item and internal consistency of AQ has been studied. A total of 52 young adults on the autism spectrum (39 males and 13 females) and 1686 controls (577 males and 1109 females) took part in this study. Results show that individuals on the autism spectrum have higher scores than same-gender controls. AQ discriminates quite well males on the autism spectrum from control males but only fairly females on the autism spectrum from control females. In item analysis most statistically significant differences between groups were found in items measuring social skills and communication

Dynamic lag analysis reveals atypical brain information flow in autism spectrum disorder

Abstract This study investigated whole‐brain dynamic lag pattern variations between neurotypical (NT) individuals and individuals with autism spectrum disorder (ASD) by applying a novel technique called dynamic lag analysis (DLA). The use of 3D magnetic resonance encephalography data with repetition time = 100 msec enables highly accurate analysis of the spread of activity between brain networks. Sixteen resting‐state networks (RSNs) with the highest spatial correlation between NT individuals (n = 20) and individuals with ASD (n = 20) were analyzed. The dynamic lag pattern variation between each RSN pair was investigated using DLA, which measures time lag variation between each RSN pair combination and statistically defines how these lag patterns are altered between ASD and NT groups. DLA analyses indicated that 10.8% of the 120 RSN pairs had statistically significant (P‐value <0.003) dynamic lag pattern differences that survived correction with surrogate data thresholding. Alterations in lag patterns were concentrated in salience, executive, visual, and default‐mode networks, supporting earlier findings of impaired brain connectivity in these regions in ASD. 92.3% and 84.6% of the significant RSN pairs revealed shorter mean and median temporal lags in ASD versus NT, respectively. Taken together, these results suggest that altered lag patterns indicating atypical spread of activity between large‐scale functional brain networks may contribute to the ASD phenotype