Factors of Activism; Identification and Promotion to Increase Global Equity

The purpose of this paper is to use a critical consciousness framework to analyze two possible factors that may contribute to individual levels of civic engagement, how these factors can operate within a global framework, and how these factors may be promoted through educational institutions to increase equity in societies around the globe. The data analyzed for this study comes from data collected as part of a study of beliefs and actions regarding social justice issues on the University of Washington Tacoma campus. For this paper, the two factors being studied as mediators in the relationship between awareness of social inequity (critical reflection) and the actions taken to address those inequalities (critical action) are empathy and social justice identity. Empathy is an innate human trait that can be enhanced through purposeful instruction and may be responsible for motivating individuals to engage in causes that do not directly impact them. By contrast, social justice identity is conceptualized as a stable construct, similar to a worldview belief or personality factor, and therefore is less likely to be influenced by an education-based intervention but may still be important to the promotion of activism behaviors. The results of statistical mediation analyses indicate that empathy and social justice identity both are partial mediators in the relationship between critical reflection and critical action. However, social justice identity demonstrated a larger mediating effect. Lastly, implications of findings and potential intervention programs aimed at promoting civically engaged citizens in societies worldwide using educational institutions are discussed

Re-Examining an Air Mass-Based Approach to Detecting Structural Climate Change, 1948-2011

Air mass-based approaches to observing changes in climate can have considerable value beyond simple trends of temperature and moisture, providing more thorough understanding of structural climate patterns. Few methodologies have adequately characterized recent air mass modification, however. This research seeks to update and improve upon the methods of a prior study, providing new data from 1948-2011, as well as more rigorous statistical analyses. Air mass types were created, and monthly averages of temperature, dewpoint, and relative frequency were calculated for each of the air masses in all four seasons; then the time series were submitted to regression analysis. The results of this re-analysis show an increase in warm air masses at the expense of cool air masses coinciding with the patterns of surface temperature and air mass warming seen in other recent studies. Some changes in the behavior of these air masses were noted, however, along with new variations in the character of others. These air mass trends have conceivable ties to prior general circulation patterns. Assuming that previous patterns have continued a possible increase in troughs, with a simultaneous decrease in ridges, in the western United States may be occurring, while new patterns of air mass source region modification and air mass mixing could also exist. Systematic warming of air masses also has conceivable, though rather modest relationships with large scale circulation patterns, including positive phases of the Arctic Oscillation (AO) and North Atlantic Oscillation (NAO), as well as contraction of the circumpolar vortex

Mycoplasma, Ureaplasma, and Adverse Pregnancy Outcomes: A Fresh Look

Recent work on the Molicutes that associate with genital tract tissues focuses on four species that may be of interest in potential maternal, fetal, and neonatal infection and in contributing to adverse pregnancy outcomes. Mycoplasma hominis and Ureaplasma urealyticum have historically been the subject of attention, but Mycoplasma genitalis which causes male urethritis in addition to colonizing the female genital tract and the division of Ureaplasma into two species, urealyticum and parvum, has also added new taxonomic clarity. The role of these genital tract inhabitants in infection during pregnancy and their ability to invade and infect placental and fetal tissue is discussed. In particular, the role of some of these organisms in prematurity may be mechanistically related to their ability to induce inflammatory cytokines, thereby triggering pathways leading to preterm labor. A review of this intensifying exploration of the mycoplasmas in relation to pregnancy yields several questions which will be important to examine in future research

Progesterone Interactions with the Cervix: Translational Implications for Term and Preterm Birth

The uterine cervix plays a vital role in maintaining pregnancy and an equally important role in allowing parturition to occur. Progesterone, either endogenously produced or supplied exogenously, supports the function of the cervix in sustaining intrauterine pregnancy, and the withdrawal of progesterone, either through natural processes or pharmacologic intervention, leads to delivery which underscores the importance of the progesterone's biological activities manifest in normal gestation and pregnancy that ends prematurely. Research crossing many scientific disciplines has demonstrated that progesterone is a pleotropic compound that affects the cervix through cytoplasmic and membrane receptors with profound effects on cellular and molecular functions that influence inflammatory cascades and extracellular matrix, both of which have consequences for parturition. Beyond the local cell and molecular biology of progesterone, it has systemic effects of relevance to pregnancy as well. This paper examines the biology of the cervix from its gross to cellular structure and biological activities of its cell and molecular processes that may be affected by progesterone. The implications of these processes for preterm birth are explored, and direction of current research is in relation to translational medicine implications for diagnostic, prognostic, and therapeutic approaches to threatened preterm birth

The Thousand Asteroid Light Curve Survey

We present the results of our Thousand Asteroid Light Curve Survey (TALCS) conducted with the Canada-France-Hawaii Telescope in September 2006. Our untargeted survey detected 828 Main Belt asteroids to a limiting magnitude of g'~22.5 corresponding to a diameter range of 0.4 km <= D <= 10 km. Of these, 278 objects had photometry of sufficient quality to perform rotation period fits. We debiased the observations and light curve fitting process to determine the true distribution of rotation periods and light curve amplitudes of Main Belt asteroids. We confirm a previously reported excess in the fraction of fast rotators but find a much larger excess of slow rotating asteroids (~15% of our sample). A few percent of objects in the TALCS size range have large light curve amplitudes of ~1 mag. Fits to the debiased distribution of light curve amplitudes indicate that the distribution of triaxial ellipsoid asteroid shapes is proportional to the square of the axis-ratio, (b/a)^2, and may be bi-modal. Finally, we find six objects with rotation periods that may be less than 2 hours with diameters between 400 m and 1.5 km, well above the break-up limit for a gravitationally-bound aggregate. Our debiased data indicate that this population represents <4% of the Main Belt in the 1-10 km size range.Comment: Accepted to Icarus. Full tables to appear there in electronic format, or contact autho

Transition-Metal Isocorroles as Singlet Oxygen Sensitizers

Building on a highly efficient synthesis of pyrrole-appended isocorroles, we have worked out conditions for manganese, palladium, and platinum insertion into free-base 5/10-(2-pyrrolyl)-5,10,15-tris(4-methylphenyl)isocorrole, H2[5/10-(2-py)- TpMePiC]. Platinum insertion proved exceedingly challenging but was finally accomplished with cis-Pt(PhCN)2Cl2. All the complexes proved weakly phosphorescent in the near-infrared under ambient conditions, with a maximum phosphorescence quantum yield of 0.1% observed for Pd[5-(2-py)TpMePiC]. The emission maximum was found to exhibit a strong metal ion dependence for the 5-regioisomeric complexes but not for the 10-regioisomers. Despite the low phosphorescence quantum yields, all the complexes were found to sensitize singlet oxygen formation with moderate to good efficiency, with singlet oxygen quantum yields ranging over 21−52%. With significant absorption in the near-infrared and good singlet oxygen-sensitizing ability, metalloisocorroles deserve examination as photosensitizers in the photodynamic therapy of cancer and other diseases

Rings Reconcile Genotypic and Phenotypic Evolution within the Proteobacteria.

Although prokaryotes are usually classified using molecular phylogenies instead of phenotypes after the advent of gene sequencing, neither of these methods is satisfactory because the phenotypes cannot explain the molecular trees and the trees do not fit the phenotypes. This scientific crisis still exists and the profound disconnection between these two pillars of evolutionary biology--genotypes and phenotypes--grows larger. We use rings and a genomic form of goods thinking to resolve this conundrum (McInerney JO, Cummins C, Haggerty L. 2011. Goods thinking vs. tree thinking. Mobile Genet Elements. 1:304-308; Nelson-Sathi S, et al. 2015. Origins of major archaeal clades correspond to gene acquisitions from bacteria. Nature 517:77-80). The Proteobacteria is the most speciose prokaryotic phylum known. It is an ideal phylogenetic model for reconstructing Earth's evolutionary history. It contains diverse free living, pathogenic, photosynthetic, sulfur metabolizing, and symbiotic species. Due to its large number of species (Whitman WB, Coleman DC, Wiebe WJ. 1998. Prokaryotes: the unseen majority. Proc Nat Acad Sci U S A. 95:6578-6583) it was initially expected to provide strong phylogenetic support for a proteobacterial tree of life. But despite its many species, sequence-based tree analyses are unable to resolve its topology. Here we develop new rooted ring analyses and study proteobacterial evolution. Using protein family data and new genome-based outgroup rooting procedures, we reconstruct the complex evolutionary history of the proteobacterial rings (combinations of tree-like divergences and endosymbiotic-like convergences). We identify and map the origins of major gene flows within the rooted proteobacterial rings (P &lt; 3.6 × 10(-6)) and find that the evolution of the "Alpha-," "Beta-," and "Gammaproteobacteria" is represented by a unique set of rings. Using new techniques presented here we also root these rings using outgroups. We also map the independent flows of genes involved in DNA-, RNA-, ATP-, and membrane- related processes within the Proteobacteria and thereby demonstrate that these large gene flows are consistent with endosymbioses (P &lt; 3.6 × 10(-9)). Our analyses illustrate what it means to find that a gene is present, or absent, within a gene flow, and thereby clarify the origin of the apparent conflicts between genotypes and phenotypes. Here we identify the gene flows that introduced photosynthesis into the Alpha-, Beta-, and Gammaproteobacteria from the common ancestor of the Actinobacteria and the Firmicutes. Our results also explain why rooted rings, unlike trees, are consistent with the observed genotypic and phenotypic relationships observed among the various proteobacterial classes. We find that ring phylogenies can explain the genotypes and the phenotypes of biological processes within large and complex groups like the Proteobacteria

Examining illicit cross-border drug flows within the Pacific Northwest

After the attacks of September 11th, 2001 the American government placed a new emphasis upon domestic security and scrutiny soon fell upon the US-Canada border. From 2001 to 2011 there has been a great expansion of border security on the US-Canada border. It is the objective of this thesis to examine how increases in security along the US-Canada border following 9/11 have affected or changed drug smuggling in the Pacific Northwest. It is the central hypothesis of this thesis that the smuggling of drugs produced in British Columbia for American markets has been pushed into the interior of the Pacific Northwest, both to less used ports of entry and to between ports of entry. This thesis examines an area in which there is a profound dearth of scholarly research. The hypotheses of this thesis were tested through the examination of data related to drug smuggling arrests and drug seizures at the border. Additionally, interviews with relevant border stakeholders were conducted. The central hypothesis of this thesis has not been conclusively supported by the data acquired for this research. It appears, based on the drug seizure and interviews, as if drug smuggling in the Pacific Northwest has greatly decreased following increases in border security after 9/11. The substantial reduction in the amount of marijuana seized at the US-Canada border in the Pacific Northwest is significant, but it is inconclusive as to what is directly responsible for this decrease