Maternal fluoxetine exposure alters cortical hemodynamic and calcium response of offspring to somatosensory stimuli

Epidemiological studies have found an increased incidence of neurodevelopmental disorders in populations prenatally exposed to selective serotonin reuptake inhibitors (SSRIs). Optical imaging provides a minimally invasive way to determine if perinatal SSRI exposure has long-term effects on cortical function. Herein we probed the functional neuroimaging effects of perinatal SSRI exposure in a fluoxetine (FLX)-exposed mouse model. While resting-state homotopic contralateral functional connectivity was unperturbed, the evoked cortical response to forepaw stimulation was altered in FLX mice. The stimulated cortex showed decreased activity for FLX versus controls, by both hemodynamic responses [oxyhemoglobin (Hb

Valuing the Recreational Benefits From the Creation of Nature Reserves in Irish Forests

Data from a large-scale contingent valuation study are used to investigate the effects of forest attributes on willingness to pay for forest recreation in Ireland. In particular, the presence of a nature reserve in the forest is found to significantly increase the visitors' willingness to pay. A random utility model is used to estimate the welfare change associated with the creation of nature reserves in all the Irish forests currently without one. The yearly impact on visitors' economic welfare of new nature reserves approaches half a million pounds per annum, exclusive of non recreational values.Non-market valuation, Contingent valuation, Forest attributes analysis, Nature reserves.

New Constraints on the Timing and Pattern of Deglaciation in the Húnaflói Bay Region of Northwest Iceland Using Cosmogenic 36CA Dating and Geomorphic Mapping

Understanding the evolution and timing of changes in ice sheet geometry and extent in Iceland during the Last Glacial Maximum (LGM) and subsequent deglaciation continues to stimulate much active research. Though many previous studies have advanced our knowledge of Icelandic ice sheet history preserved in marine and terrestrial settings (e.g., Andrews et al., 2000; Norðdahl et al., 2008), the timing of ice margin retreat remains largely unknown in several key regions. Recently published 36Cl surface exposure ages of bedrock surfaces and moraines in the West Fjords (Brynjólfsson et al., 2015) contribute important progress in establishing more precise age control of ice recession in northwest Iceland. In another recent study, the spatial pattern and style of deglaciation in northern Iceland have been revealed through geomorphic mapping and GIS analyses of glacial landforms (Principato et al., 2016). Additional insight comes from updated numerical modeling reconstructions, which now provide a series of glaciologically plausible Icelandic ice sheet configurations from the LGM through the last deglaciation (Patton et al., 2017). However, the optimization of ice sheet model simulations relies on critical comparisons with the available empirical record of glacial-geologic evidence and chronological control, which remains relatively limited and sparsely distributed throughout Iceland. Our investigation is motivated by the need for more accurate constraints on the deglacial history in northern Iceland, where dated terrestrial records of ice margin retreat are particularly scarce. (excerpt

A Statistical Analysis of Teacher Effectiveness Dimensions on Students Satisfaction in Kenyan Public Schools

This study aims to investigate the differential effects of teaching practices on students’ satisfaction. Their level of satisfaction based primarily on data collected through six principles of 21st century effective teaching and learning using questionnaire method randomly submitted to 600 Form Four students in Voi sub-county, Kenya. The differential effects of the six teaching practices on students’ satisfaction were analyzed using the multiple regression model technique. The results show that students’ satisfaction was positive and statistically influenced by subject mastery, innovative learning environment, commitment to teach, communicating high standards and professional development. The mean score results demonstrate that subject mastery wasthe most effective teaching practice while non-cognitive issues was the least effective teaching practice. The study provides very useful information to help policymakers in secondary school administration to evaluate the level of teacher quality dimensions in their institutions and the 21st century effective teacher practices on students’ satisfaction. Furthermore, the conceptual relationships model can give deeper understanding of the effective teaching practices that needs prioritization by school management. Social change implications are that teachers may begin to use practices that more effectively engage learners, leading to greater satisfaction and a likely increase in the students’ success

Science with High Spatial Resolution Far-Infrared Data

The goal of this workshop was to discuss new science and techniques relevant to high spatial resolution processing of far-infrared data, with particular focus on high resolution processing of IRAS data. Users of the maximum correlation method, maximum entropy, and other resolution enhancement algorithms applicable to far-infrared data gathered at the Infrared Processing and Analysis Center (IPAC) for two days in June 1993 to compare techniques and discuss new results. During a special session on the third day, interested astronomers were introduced to IRAS HIRES processing, which is IPAC's implementation of the maximum correlation method to the IRAS data. Topics discussed during the workshop included: (1) image reconstruction; (2) random noise; (3) imagery; (4) interacting galaxies; (5) spiral galaxies; (6) galactic dust and elliptical galaxies; (7) star formation in Seyfert galaxies; (8) wavelet analysis; and (9) supernova remnants

Occurrence of the Old World bug Megacopta cribraria (Fabricius) (Heteroptera: Plataspidae) in Georgia: a serious home invader and potential legume pest

Specimens of Megacopta cribraria (Fabricius) were collected in northern Georgia in late October 2009, where they were invading homes in large numbers. This is the first known occurrence of this species and the family Plataspidae in the New World. Megacopta cribraria was previously known from Asia and Australia. A key is provided to separate Plataspidae from other families of Pentatomoidea in America North of Mexico. A diagnosis and figures are provided to facilitate recognition of M. cribraria. Reported host plants and other aspects of the biology of this species are reviewed. Megacopta cribraria is considered a pest of numerous legumes in Asia, has the potential to provide biological control of kudzu, Pueraria montana var. lobata (Willd.) Ohwi, (Fabaceae) and likely will continue to be a household pest in the vicinity of kudzu fields as well as become a pest of North American legume crops

Should COVID Vaccination Be Required in Heart Transplantation & Left Ventricular Assist Device Implantation?

This letter to the editor does not have an abstract

A Magnetic and Moessbauer Spectral Study of Core/Shell Structured Fe/Au Nanoparticles

Fe/Au nanoparticles have been chemically synthesized through a reverse micelle reaction and investigated by both conventional and synchrotron based x-ray diffraction and by magnetic and Moessbauer spectral studies. The powder x-ray diffraction patterns reveal both the presence of crystalline alpha-iron and gold and the absence of any crystalline iron oxides or other crystalline products. First-order reversal curves, along with the major hysteresis loops of the Fe/Au nanoparticles have been measured as a function of time in order to investigate the evolution of their magnetic properties. The iron-57 Moessbauer spectra of both uncoated iron nanoparticles and the Fe/Au nanoparticles have been measured at 78 and 295 K and indicate that two major iron containing components are present, namely the expected alpha-iron and the unexpected amorphous Fe1-xBx alloy; several poorly crystallized ordered iron(III) oxide components as well as paramagnetic iron(II) and iron(III) components are also observed. These results indicate that the Fe-core/Au-shell nanoparticles synthesized through reverse micelles are far more complex that had been believed.Comment: 31 pages, 1 table, 8 figures, to appear in Chemistry of Material