Validación de la versión española del Cuestionario Breve de Evitación Experiencial (BEAQ) en población clínica

The Brief Experiential Avoidance Questionnaire (BEAQ) has been suggested as the most appropriate instrument for measuring experiential avoidance. However, no Spanish validation has been published. The aim of this study was to validate a Spanish version of the BEAQ in a clinical sample treated at a community mental health unit. Methods: Participants (N = 332) completed the BEAQ as well as other self-report measures of experiential avoidance and psychopathology. Results: Internal consistency was satisfactory (α = .82). No statistically significant gender differences were found in the BEAQ scores. The data also showed high test-retest reliability after four to six weeks, acceptable concurrent validity with another experiential avoidance measure and acceptable convergent validity with the psychopathology measure. The principal component analysis, forcing the one factor solution proposed in the original scale, produced indicators similar to the English version of the BEAQ. Conclusions: These results firmly support the reliability and validity of this Spanish validation, stressing its usefulness as a measure of experiential avoidance in clinical populations.Antecedentes: el Cuestionario Breve de Evitación Experiencial (BEAQ) ha sido propuesto como el instrumento más adecuado para medir la evitación experiencial. Sin embargo, todavía no ha sido publicada ninguna validación en español. Por lo tanto, el objetivo del presente estudio ha sido la validación de una versión española del BEAQ, en una muestra clínica atendida en un Centro de Salud Mental Comunitario. Método: los participantes (N = 332) completaron el BEAQ, así como otras medidas de autoinforme de evitación experiencial y psicopatología. Resultados: la consistencia interna fue satisfactoria (α = .82). No se encontraron diferencias de género estadísticamente significativas en las puntuaciones del BEAQ. Los datos también mostraron una alta fiabilidad test-retest en un intervalo de cuatro a seis semanas, validez concurrente aceptable con otra medida de evitación experiencial y validez convergente aceptable con la medida de psicopatología. El análisis de componentes principales forzando a la solución de un factor, como se propuso en la escala original, obtuvo unos indicadores similares a los obtenidos en dicha versión inglesa. Conclusiones: los resultados confirman la adecuada fiabilidad y validez de la presente versión española del BEAQ, destacando su utilidad como medida de la evitación experiencial en población clínica

A 64-channel inductively-powered neural recording sensor array

This paper reports a 64-channel inductively powered neural recording sensor array. Neural signals are acquired, filtered, digitized and compressed in the channels. Additionally, each channel implements a local auto-calibration mechanism which configures the transfer characteristics of the recording site. The system has two operation modes; in one case the information captured by the channels is sent as uncompressed raw data; in the other, feature vectors extracted from the detected neural spikes are transmitted. Data streams coming from the channels are serialized by an embedded digital processor and transferred to the outside by means of the same inductive link used for powering the system. Simulation results show that the power consumption of the complete system is 377μW.Ministerio de Ciencia e Innovación TEC2009-0844

A power efficient neural spike recording channel with data bandwidth reduction

This paper presents a mixed-signal neural spike recording channel which features, as an added value, a simple and low-power data compression mechanism. The channel uses a band-limited differential low noise amplifier and a binary search data converter, together with other digital and analog blocks for control, programming and spike characterization. The channel offers a self-calibration operation mode and it can be configured both for signal tracking (to raw digitize the acquired neural waveform) and feature extraction (to build a first-order PWL approximation of the spikes). The prototype has been fabricated in a standard CMOS 0.13μm and occupies 400μm×400μm. The overall power consumption of the channel during signal tracking is 2.8μW and increases to 3.0μW average when the feature extraction operation mode is programmed.Ministerio de Ciencia e Innovación TEC2009-08447Junta de Andalucía TIC-0281

A mixed-signal integrated circuit for FM-DCSK modulation

This paper presents a mixed-signal application-specific integrated circuit (ASIC) for a frequency-modulated differential chaos shift keying (FM-DCSK) communication system. The chip is conceived to serve as an experimental platform for the evaluation of the FM-DCSK modulation scheme, and includes several programming features toward this goal. The operation of the ASIC is herein illustrated for a data rate of 500 kb/s and a transmission bandwidth in the range of 17 MHz. Using signals acquired from the test platform, bit error rate (BER) estimations of the overall FM-DCSK communication link have been obtained assuming wireless transmission at the 2.4-GHz ISM band. Under all tested propagation conditions, including multipath effects, the system obtains a BER = 10-3 for Eb/No lower than 28 dB.Ministerio de Ciencia y Tecnología TIC2003-0235

On the Analysis and Detection of Flames Withan Asynchronous Spiking Image Sensor

We have investigated the capabilities of a customasynchronous spiking image sensor operating in the NearInfrared band to study flame radiation emissions, monitortheir transient activity, and detect their presence. Asynchronoussensors have inherent capabilities, i.e., good temporal resolution,high dynamic range, and low data redundancy. This makesthem competitive against infrared (IR) cameras and CMOSframe-based NIR imagers. In this paper, we analyze, discuss,and compare the experimental data measured with our sensoragainst results obtained with conventional devices. A set ofmeasurements have been taken to study the flame emissionlevels and their transient variations. Moreover, a flame detectionalgorithm, adapted to our sensor asynchronous outputs, has beendeveloped. Results show that asynchronous spiking sensors havean excellent potential for flame analysis and monitoring.Universidad de Cádiz PR2016-07Ministerio de Economía y Competitividad TEC2015-66878-C3-1-RJunta de Andalucía TIC 2012-2338Office of Naval Research (USA) N00014141035

Baseband-processor for a passive UHF RFID transponder

This paper describes the design of a digital processor targeting the Class-1 Generation-2 EPC Protocol for UHF RFID transponders, and proposes different techniques for reducing its power consumption. The processor has been implemented in a 0.35μm CMOS technology process using automatic tools for both the logic synthesis and layout. Post-layout simulations confirm the fully functionality of the prototype and predict a worst-case power consumption of only 2.9μA at 1.2V supply.Ministerio de Educación y Ciencia TEC2006-03022, TEC2009-08447Junta de Andalucía TIC-0281

A sun sensor implemented with an asynchronous luminance vision sensor

A sun sensor implemented with a spiking pixel matrix is reported. It is the very first one based on an asynchronous event-based pixel array. A paradigm associated to classic digital sun sensors is solved with this approach. Only pixels illuminated by the sun light are readout. Hence, the output data flow is quite reduced. The computational load to resolve the sun position is quite low, comparing to prior sensors. Sensor's latency is in the order of milliseconds. The advantages over implementations with APS pixels are more reduced data flow, less latency, and higher dynamic range.Universidad de Cádiz PR2016-072Ministerio de Economía y Competitividad TEC2015-66878- C3-1-RJunta de Andalucía TIC 2012-2338Office of Naval Research (USA) N00014141035

Enhancement and inhibition effects on the corneal permeability of timolol maleate: polymers, cyclodextrins and chelating agents

This study investigates how both bioadhesive polymers (chitosan, hyaluronic acid and alginate) and permeability enhancers (ethylene glycol- bis(2-aminoethylether)- N, N, N', N'- tetraacetic acid (EGTA) and hydroxypropyl-ß-cyclodextrin) influence the permeability of the anti-glaucoma drug timolol maleate through ex vivo bovine corneas. Our results showed that only the permeability enhancers alone were able to increase drug permeability, whereas the polymers significantly reduced drug permeation, and however, they increased the pre-corneal residence of timolol. Ternary systems (polymer-enhancer-drug) showed a reduced drug permeability compared to the polymers alone. Fluorescence microscopy analysis of the epithelium surface confirmed there was no evidence of epithelial disruption caused by these formulations, suggesting that polymer-enhancer interactions reduce drug solubilization and counteract the disruptive effect of the permeability enhancers on the surface of the cornea. Further mucoadhesive tests, revealed a stable interaction of chitosan and hyaluronic acid with the epithelium, while alginate showed poor mucoadhesive properties. The differences in mucoadhesion correlated with the permeability of timolol maleate observed, i.e. formulations containing mucoadhesive polymers showed lower drug permeabilities. The results of the present study indicate polymers acting as an additional barrier towards drug permeability which is even more evident in the presence of permeability enhancers like EGTA and hydroxypropyl-ß-cyclodextrin. Then, this study highlights the need to adequately select additives intended for ocular applications since interactions between them can have opposite results to what expected in terms of drug permeability