Utilização da simulação computacional na verificação da cooperação de uma população em um ambiente simulado = Use of computer simulation to verify the cooperation of a population in a simulated environment

En el presente artículo realizamos un análisisde comportamientos de cooperación enambiente simulado. El presente estudio tienecomo finalidad observar los resultados de la interacciónde los caracteres egoísta, vengativo yaltruista en constante interacción a lo largo degeneraciones. Durante el proceso se desarrollaronalgoritmos que emulan una de las aplicacionesde la teoría de los juegos, el dilemadel prisionero y otro que utiliza la forma en quelos autómatas móviles se mueven-sedientosde una malla virtual. La contribución que conseguimoses dar un valor porcentual máximo auna población aceptada con carácter egoísta yverificar que los caracteres vengativo y altruistatienen un tiempo de vida muy próximo

Questionário De Percepção Dos Pais - Q.P.P.

Based on the relevant psychological and sociologicalliterature, a 43 item scale (QPP) was built to assess subjects'perceptions of their own parents. A factorial analysis of the answers of574 high-school and college students revealed four factors in thepaternal figure: Friendly companionship, punitive discipline, lax discipline,and centration in the child. Four factors also appeared in thematernal figure: Friendly intimacy, overprotection, lax discipline, andpunishment. Two second-order factors appeared in both parentalfigures: Love and discipline. Ali factors showsatisfactory reliability. Theinstrument as well as the form of its practical use are presented.Com base na literatura psicológica e sociológica pertinente, foi construído um instrumento de 43 itens (QPP) para avaliar a percepção que os filhos possuem de seus pais. A validação fatorial foi efetuada com uma amostra de 574 estudantes de 2? grau e superior. Quatro fatores apareceram na figura do pai: companheiro amigo, disciplina punitiva, disciplina lassa, centralização no filho; quatro fatores surgiram também na figura da mãe: intimidade amiga, superproteção, controle lasso, punição. Esses quatro fatores em ambas as figuras parentais se agrupam em dois fatores de segunda ordem: amore disciplina. Todos eles possuem índices satisfatórios de precisão. São apresentados igualmente o instrumento e o seu modo de utilização

A novel methodology to assess the relaxation rate of the intervertebral disc by increments on intradiscal pressure

Publicado em "Applied mechanics and materials, vol. 664 (2014) pp 379-383"The Intervertebral Disc (IVD) is subjected to several types of loading during daily routine events. However, the overloading on this structure induces higher Intradiscal Pressure (IDP), which could cause severe damage on its structure. This study describes a new approach to that allows monitorize and pressurize nuclear region of the IVD, with a cartilaginous endplate access, by the insertion of an external fluid, while a Motion Segment (MS-assembly composed by vertebra-disc-vertebra) is compressed at a physiological load. This methodology includes the use of a pneumatic structure that applies a certain pressure on the hydrostatic system, forcing a fluid to enter into the MS through a screw, with a drilled hollow along its entire length. Preliminary results indicated that this methodology presents high potential to efficiently pressurize the IVD, providing a useful tool to better understand the response of this structure under pressure.EC -European Commission(NMP-2009-SMALL-3-CP-FP 246351

A novel methodology for measurement of the intradiscal pressure and height disc variation of intervertebral disc under compression

The intervertebral disc (IVD) is subjected to several types of loading during daily routine events. However, the overloading on this structure induces higher intradiscal pressure (IDP), which could cause severe damage on its structure. This study describes a new approach to monitor IDP and determine the height disc variation by applying external pressure, while a motion segment (assembly composed by vertebra-disc-vertebra) compressed at a physiological load. This methodology includes the use of a pneumatic structure that applies a certain pressure on the hydrostatic system, forcing a fluid to enter into the motion segment, through a screw with a drilled hollow along its entire length with an internal bore. Preliminary results indicates these methodology presents high potential to efficiently pressurize the IVD, providing a useful tool to better understand the response of this structure under pressure

Development of a Novel Biosensor Using Cationic Antimicrobial Peptide and Nickel Phthalocyanine Ultrathin Films for Electrochemical Detection of Dopamine

The antimicrobial peptide dermaseptin 01 (DS 01), from the skin secretion of Phyllomedusa hypochondrialis frogs, was immobilized in nanostructured layered films in conjunction with nickel tetrasulfonated phthalocyanines (NiTsPc), widely used in electronic devices, using layer-by-layer technique. The films were used as a biosensor to detect the presence of dopamine (DA), a neurotransmitter associated with diseases such as Alzheimer's and Parkinson's, with detection limits in the order of 10−6 mol L−1. The use of DS 01 in LbL film generated selectivity in the detection of DA despite the presence of ascorbic acid found in biological fluids. This work is the first to report that the antimicrobial peptide and NiTsPc LbL film exhibits electroanalytical activity to DA oxidation. The selectivity in the detection of DA is a fundamental aspect for the development of electrochemical sensors with potential applications in the biomedical and pharmaceutical industries

Development of a Novel Biosensor Using Cationic Antimicrobial Peptide and Nickel Phthalocyanine Ultrathin Films for Electrochemical Detection of Dopamine

The antimicrobial peptide dermaseptin 01 (DS 01), from the skin secretion of Phyllomedusa hypochondrialis frogs, was immobilized in nanostructured layered films in conjunction with nickel tetrasulfonated phthalocyanines (NiTsPc), widely used in electronic devices, using layer-by-layer technique. The films were used as a biosensor to detect the presence of dopamine (DA), a neurotransmitter associated with diseases such as Alzheimer's and Parkinson's, with detection limits in the order of 10−6 mol L−1. The use of DS 01 in LbL film generated selectivity in the detection of DA despite the presence of ascorbic acid found in biological fluids. This work is the first to report that the antimicrobial peptide and NiTsPc LbL film exhibits electroanalytical activity to DA oxidation. The selectivity in the detection of DA is a fundamental aspect for the development of electrochemical sensors with potential applications in the biomedical and pharmaceutical industries

Evaluación del vault en la adaptación de lentes de contacto esclerales con un biómetro óptico

[Extracto] Justificación y objetivos -   La tomografía de coherencia óptica (OCT) anterior es un método óptico que permite evaluar la separación entre la lente de contacto y la córnea – vault – en la adaptación de lentes de contacto esclerales (LCE). Sin embargo, el costo considerable de este tipo de equipo es un obstáculo a la aplicación en usuarios de LCE, especialmente en el ámbito de investigación. [...]info:eu-repo/semantics/publishedVersio

Clinical outcome of renal transplant patients after coronary stenting

OBJECTIVE: To assess the clinical outcome of renal transplant patients who developed coronary artery disease and were treated with coronary stenting (TCA-ST). METHODS: A total of 3,334 renal transplants were performed in our service - Hospital do Rim e Hipertensão - HRH (Kidney and Hypertension Hospital) from July, 1998 to November, 2004. During this period, 33 of the renal transplant patients underwent TCA-ST to treat 62 severe stenoses in 54 coronary arteries. A retrospective analysis was performed with renal transplant patients undergoing TCA-ST at HRH. The clinical events were registered using medical charts, medical visits and phone calls. RESULTS: During the 30-month clinical follow-up after TCA-ST, 67% of the patients remained asymptomatic, 18% presented stable angina, 6% presented acute coronary syndrome without ST-segment elevation (ACSWSTE), and 3% presented acute coronary syndrome with ST-segment elevation (ACSSTE). No strokes, CHF or cardiac deaths were observed. Three non-cardiac deaths occurred. A restenosis rate of 9% was observed, which is comparable to those found in studies on drug-eluting stents. CONCLUSION: In conclusion, renal transplant patients who developed CAD and were treated with coronary stenting had a low rate of in-stent restenosis, probably related to the immunosuppressive regimen given to prevent kidney rejection.OBJETIVO: Avaliar a evolução clínica de pacientes submetidos a transplante de rim, portadores de doença arterial coronariana, que foram tratados com implante de stent coronariano (ATC-ST). MÉTODOS: Entre julho de 1998 e novembro de 2004, foram realizados, no total, 3.334 transplantes de rim em nossa Instituição (Hospital do Rim e Hipertensão). Desse total, 33 pacientes previamente submetidos a transplante de rim fizeram ATC-ST para o tratamento de 62 estenoses graves em 54 artérias coronárias, nos quais foi realizada análise retrospectiva. O registro dos eventos clínicos foi feito por meio de análise do prontuário médico, consulta médica e ligações telefônicas. RESULTADOS: No seguimento clínico de 30 meses, após a ATC-ST, observou-se que 67% dos pacientes permaneceram assintomáticos, 18% dos pacientes apresentaram quadro de angina estável, 6% apresentaram síndrome coronariana aguda sem supra de ST e 3% apresentaram síndrome coronariana aguda com supra de ST. Não houve pacientes com acidente vascular cerebral, insuficiência cardíaca congestiva ou morte cardíaca. Houve três mortes não-cardíacas. Foi observado índice de reestenose de 9%, que é comparável ao dos estudos de stent farmacológico. CONCLUSÃO: Concluímos que pacientes submetidos a transplante de rim que desenvolveram doença arterial coronariana e que foram tratados com stent coronariano tiveram baixo porcentual de reestenose clínica, provavelmente relacionado ao regime de imunossupressão administrado para evitar rejeição renal.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Hospital do Rim e HipertensãoUNIFESP, EPM, Hospital do Rim e HipertensãoSciEL

A comparison of methods of handling precocious maize straw at the time of dry season common bean planting

Em Leopoldina, MC, compararam-se os seguintes tratamentos de manejo da palha de milho precoce na época de plantio do feijão da seca: a) permanência do milho em pé; b) dobramento do milho após o plantio do feijão; c) cordões das plantas de milho em suas próprias fileiras, após o plantio da leguminosa; d) corte das plantas de milho em pedaços de 30 a 40cm, para distribuí-los pela parcela, após o plantio do feijão; e) retirada do milho da parcela, que foi arada e gradada antes do plantio do feijão. Nos tratamentos e, de e, as espigas de milho foram colhidas antes da semeadura do feijão, enquanto em a e b ambas as culturas foram colhidas juntas, o que permitiu grande ataque de insetos aos grãos de milho. O melhor tratamento, considerando ambas as culturas, foi o C.In this study, the following treatments of handling precocious maize straw, during the time of dry season common bean planting were compared in Leopoldina, MC, Brazil: a) maize planta erect: b) 'breaking over" maize planta after bean seeding; c) maize planta cut and piled in their own rows after bean seeding; d) maize plants cut in pieces 30 to 40cm long and scattered on the plot alter bean seeding; e) maize taken off from the plot, prepared with plow and harrow, before bean seeding. In treatment c, d, and e maize ears were harvested before bean planting, whereas in a and b both crops were harvested when the beans were mature. The delay in maize harvest, in treatments a and b, permitted a greater insect attack on the kemels. The best treatment, considering both crops, was c

Reparo de resinas compostas envelhecidas e mediadas por diferentes materiais restauradores

The aim of this study was to evaluate the shear bond strength of resin composite repairs with and without aging of the surface to be repaired, using different adhesive systems and resin composites. Ninety specimens were prepared: 10 for the Control Group (GC - without repair); 40 for Group I (GI - repairs after 7 days) and 40 for Group II (GII - repairs after 180 days). Groups I and II were divided into 4 subgroups of 10 specimens each, according to the adhesive system and composite resin used: A) Adper Scotch Bond Multipurpose + Filtek Z350 XT; B) Adper Single Bond Plus + Filtek Z350 XT; C) Adper Scotch Bond Multipurpose + Esthet-X; D) Adper Single Bond Plus + Esthet-X. The specimens were tested for shear strength in a universal testing machine. The results were analyzed by two-factor one-way ANOVA and Fisher’s post hoc tests (alpha=0.05). The control group had better performance than the other groups. There was no significant difference when comparing different adhesive systems and composite resins. Repairs performed at 7 days were better than those performed at 180 days. The composite repairs decreased the mechanical strength of the restoration. Aging of the resin substrate may decrease repair bond strength over time, regardless of the type of adhesive systems and resin composites used.Avaliar a resistência de união ao cisalhamento de reparos de resina composta com e sem envelhecimento da superfície a ser reparada, utilizando diferentes sistemas adesivos. Noventa corpos de prova foram confeccionados sendo: 10 para o Grupo Controle (GC - sem reparo); 40 para o Grupo I (GI - reparos após 7 dias) e 40 para o Grupo II (GII – reparos após 180 dias). Para os reparos, os grupos GI e GII foram subdivididos em 4 subgrupos com 10 corpos de prova, variando o sistema adesivo e a resina composta: A) Adper Scotch Bond Multipurpose+ Filtek Z350XT; B)Adper Single Bond Plus+ Filtek Z350XT; C)Adper Scotch Bond Multipurpose+ Esthet-X; D) Adper Single Bond Plus+ Esthet-X. Os corpos de prova foram submetidos a uma força de cisalhamento em uma máquina de ensaio universal (EMIC). Os resultados foram analisados pelo teste estatístico Anova dois fatores, seguido pelo teste de Fisher´s. Observou-se melhor comportamento do grupo controle sobre os demais grupos, além disso, os reparos realizados aos 7 dias foram superiores aos dos realizados em 180 dias. Não houve diferença significativaquando se comparou diferentes sistemas adesivos e resinas compostas. Os reparos de resina composta diminuem a resistência mecânica da restauração.O envelheci mento do substrato de resina pode diminuir a resistência ao reparo ao longo do tempo, independentemente do tipo de sistemas adesivos e resinas compostas utilizados