326 research outputs found

    The Recent Debate Between Aristotelians and Thomists About Esse ipsum

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    En este artículo se presenta la crítica que vierte el aristotelismo sobre la concepción de Dios en Tomás de Aquino como Esse ipsum subsistens, a través de uno de los filósofos aristotélicos más relevantes de la actualidad, Enrico Berti. A continuación, se desarrolla la respuesta que ha ofrecido el tomista Stephen L. Brock en su defensa del ipsum esse, haciendo referencia a las últimas disputas sobre dicho argumento en el así denominado «tomismo analítico». De este modo, se pretende exponer el estatuto del debate reciente entre aristotélicos y tomistas sobre la cuestión de Dios como Esse ipsum subsistens, para comprobar si la histórica incompatibilidad entre ambas concepciones metafísicas resulta ser definitivaThis article first presents the aristotelian criticism of the conception of God as Esse ipsum subsistensin Thomas Aquinas, through one of the most important aristotelian philosophers today, Enrico Berti. Then the answer offered by the thomist Stephen L. Brock in his defense of the ipsum esse is set forth, with reference to the recent disputes regarding this issue in the socalled «analytical thomism». The aim is to determine the status of the recent debate between aristotelians and thomists regarding the question of God as Esse ipsum subsistens, in order to ascertain whether the historical incompatibility between the two metaphysical conceptions is to be considered definitiv

    Application of HOSVD to Aerodynamics. The Problem of Shock Waves

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    Efficient interpolation in aerodynamic databases is important for the aeronautic industry because of its implication on both the cost and time needed to complete design cycles. In this study a method based on high-order singular value decomposition is presented focusing on the problems associated with the shock wave like structures that do not suit well with this kind of methods. To illustrate the methodology, the flow around a two-dimensional airfoil is considered at a Reynolds number of 20 × 106 with three free parameters, namely, the Mach number, the angle of attack, and the flap deflection angle in the ranges of [0.4, 0.8], [¿3º, 3º], and [¿5º, 5º], respectively. The method is robust in the sense of being able to deal with very different flow topologies

    El estatuto de la forma en el libro "Zeta" de la "Metafísica"

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    This paper examines the status of form in the book Zeta of the Metaphysics from the perspective of contemporary debates. For this purpose, the paper discusses critical passages that led to the interpretation of Aristotelian forms in terms of particularity or universality. The aim is to determine if form in Aristotle is particular, i.e. unique and peculiar, or universal, i.e. common and shared by several individuals.En este artículo se presenta el estatuto de la forma en el libro Zeta de la Metafísica, a partir del debate contemporáneo. Para ello, se comentan los pasajes fundamentales de Zeta que han dado lugar a interpretar la forma en términos de particularidad o universalidad. El propósito de este trabajo consiste en mostrar si la forma en Aristóteles es particular, es decir, única y peculiar, o es universal, es decir, común y compartida por varios individuos

    A Legal and Forensic Medicine Approach to Police Physical Intervention Techniques in High-Risk Situations

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    Background: The physical intervention techniques (PITs) typically used by the police in troublesome situations are examined in terms of injuring potential depending on whether they target a body zone of high, medium or low vulnerability. Based on legal and forensic considerations, and principles of congruence, opportunity and proportionality, a need exists to favor opponent locking and arrest techniques targeting non-vulnerable zones to minimize the risk of severe damage. Methods: A search of the training manuals for the different kind of law of enforcement officers was carried out. Revision of injuries was available from electronic databases of academic o medical journals. Results: Three different locking and arrest PITs based on operational tactical procedures (OTP) that avoid zones of high or medium vulnerability are proposed. The new techniques use blocking, diverting and grabbing of the upper and lower limbs, followed by dislocation and locking of the same targets. Conclusions: The damaging potential of such PITs was assessed in terms of anatomical region and most were found to have a high risk of severe damage. The alternative PITs proposed here, which rely on OTP, improve in legal and forensic medical terms on existing choices and dramatically reduce the risk of injuring arrestees

    Cerium oxide nanoparticles regulate insulin sensitivity and oxidative markers in 3T3-L1 adipocytes and C2C12 myotubes

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    Insulin resistance is associated with oxidative stress, mitochondrial dysfunction, and a chronic low-grade inflammatory status. In this sense, cerium oxide nanoparticles (CeO2 NPs) are promising nanomaterials with antioxidant and anti-inflammatory properties. Thus, we aimed to evaluate the effect of CeO2 NPs in mouse 3T3-L1 adipocytes, RAW 264.7 macrophages, and C2C12 myotubes under control or proinflammatory conditions. Macrophages were treated with LPS, and both adipocytes and myotubes with conditioned medium (25% LPS-activated macrophages medium) to promote inflammation. CeO2 NPs showed a mean size of ≤25.3 nm (96.7%) and a zeta potential of mV, suitable for cell internalization. CeO2 NPs reduced extracellular reactive oxygen species (ROS) in adipocytes with inflammation while increased in myotubes with control medium. The CeO2 NPs increased mitochondrial content was observed in adipocytes under proinflammatory conditions. Furthermore, the expression of Adipoq and Il10 increased in adipocytes treated with CeO2 NPs. In myotubes, both Il1b and Adipoq were downregulated while Irs1 was upregulated. Overall, our results suggest that CeO2 NPs could potentially have an insulin-sensitizing effect specifically on adipose tissue and skeletal muscle. However, further research is needed to confirm these findings

    Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast

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    In the present article, we describe a study of antitumor activity in breast cell lines using silver nanoparticles (Ag NPs) synthesized by a microbiological method. These Ag NPs were tested for their antitumor activity against MCF7 and T47D cancer cells and MCF10-A normal breast cell line. We analyzed cell viability, apoptosis induction, and endocytosis activity of those cell lines and we observed that the effects of the biosynthesized Ag NPs were directly related with the endocytosis activity. Moreover, Ag NPs had higher inhibition efficacy in tumor lines than in normal lines of breast cells, which is due to the higher endocytic activity of tumor cells compared to normal cells. In this way, we demonstrate that biosynthesized Ag NPs can be an alternative for the treatment of tumors.Support from Universidad Nacional de San Luis, to the Agencia Nacional de Promoción Científica y Tecnológica, from Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) (Argentina), and from GENYO, Centre for Genomics and Oncological Research: Pfizer-University of Granada, Andalusian Regional Government, Granada, Spain are acknowledged

    La integración de los stakeholders en la empresa: identificación de sus principales dimensiones

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    La importancia de los Stakeholders en el mundo empresarial actual hace que las empresas estén obligadas a tenerlos en cuenta, y les provoca la necesidad de realizar esfuerzos en integrar las demandas de sus grupos de interés (GI) en las políticas y prioridades de la firma para conseguir su satisfacción. Tras analizar los distintos aspectos que se han tenido en cuenta para analizar las relaciones con los Stakeholders, y utilizando tanto el enfoque descriptivo como normativo de la teoría, identificamos tres dimensiones en el proceso de integración de los GI: el conocimiento de los GI, su implicación en la empresa a través de la consulta y la participación y la modificación de políticas y objetivos para adaptarse a sus demandas. Estas dimensiones se identifican especialmente relevantes para conseguir la satisfacción de los grupos de interés.The importance of Stakeholders in the current managerial world is forcing companies to keep them continually in mind. In addition, it causes the necessity of carrying out efforts aimed at integrating stakeholders’ demands into their politics and priorities in order to achieve their satisfaction. After analyzing the different aspects considered in the study of relationships with Stakeholders, and using both a descriptive and normative theory scope, we identify three dimensions in the process of stakeholders´ integration: the knowledge about them, their implication in the company through consulting and participation, and finally, the modification of enterprises’ politics and objectives in order to adapt to their demands. These dimensions are considered to be of special importance in ensuring Stakeholders’ satisfaction

    El efecto indirecto sobre el rendimiento de la integración de los stakeholders

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    La literatura, tanto desde el enfoque instrumental como normativo de la Teoría de los Stakeholders, ha resaltado la influencia en el resultado de las relaciones con los grupos de interés (GI), pero este efecto se ha analizado de forma directa. En el presente trabajo, desarrollamos la influencia de la integración de los GI en el rendimiento empresarial, no de forma directa sino indirecta, a través de otras capacidades. Exponemos que la integración de los GI influye de forma indirecta sobre el rendimiento a través de otras capacidades empresariales como la innovación o el aprendizaje organizativo. Además, exponemos que este efecto indirecto se produce de dos formas: bien como elemento potenciador de esas capacidades, o bien como activo complementario sobre el resultado.Existent literature, both from the instrumental as well as the normative Stakeholders’ Theory scope, has highlighted the influence of the relationships with the stakeholders on the enterprises´ performance, but this effect has been analyzed from a direct perspective. In the current paper, we develop the influence of the stakeholders’ integration on the enterprises´ performance, not from a direct way but using an indirect perspective, through other capacities such us innovation, or organizational learning. In addition, we argue that this indirect effect takes place in two ways: as a strengthen element of those capacities, or as a complementary asset on performance

    Economic and technical evaluation of different systems of loquat protected crop

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    The culture of loquat (Eryobotria japonica Lindl.) in the region of "La Marina Baixa" has a substantial social and economic impact. In order to get earlier cropping, different systems of polietylen mesh screens have been introduced. However this cultural practice produced some negative effects, such as the increasing of "purple spot" on the fruits. Appliyng water with microsprinklers reduces the percentage of fruits affected by "purple spot". The high cost of the equipment needed to install the mesh and microsprinklers showed the need of an evaluation and comparison of all systems employed. The results and conclusions are presented in this paper
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