6,354 research outputs found

    Multicultural needs assessment of extension educators

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    "Oklahoma Cooperative Extension Service.""Cambio Center at the University of Missouri."Oklahoma State University's College of Human Sciences and the Oklahoma Cooperative Extension Service (OCES) have developed a multicultural and community engagement program to determine intercultural training needs. The program conducted a study to determine the needs for intercultural training by Extension personnel across the state of Oklahoma. The results of this study showed that OCES personnel are interested in attending intercultural training and developing their own intercultural competence to reach multicultural groups. This study helped OCES design its first intercultural competency training plan. This plan includes assessing intercultural competence and designing trainings materials using a variety of modalities such as face-to-face workshops, lectures, and online activities via Adobe Connect or Desire 2 Learn (D2L) platforms

    A field evaluation of the Hardy TB MODS Kit™ for the rapid phenotypic diagnosis of tuberculosis and multi-drug resistant tuberculosis.

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    BACKGROUND: Even though the WHO-endorsed, non-commercial MODS assay offers rapid, reliable TB liquid culture and phenotypic drug susceptibility testing (DST) at lower cost than any other diagnostic, uptake has been patchy. In part this reflects misperceptions about in-house assay quality assurance, but user convenience of one-stop procurement is also important. A commercial MODS kit was developed by Hardy Diagnostics (Santa Maria, CA, USA) with PATH (Seattle, WA, USA) to facilitate procurement, simplify procedures through readymade media, and enhance safety with a sealing silicone plate lid. Here we report the results from a large-scale field evaluation of the MODS kit in a government service laboratory. METHODS & FINDINGS: 2446 sputum samples were cultured in parallel in Lowenstein-Jensen (LJ), conventional MODS and in the MODS kit. MODS kit DST was compared with conventional MODS (direct) DST and proportion method (indirect) DST. 778 samples (31.8%) were Mycobacterium tuberculosis culture-positive. Compared to conventional MODS the sensitivity, specificity, positive, and negative predictive values (95% confidence intervals) of the MODS Kit were 99.3% (98.3-99.8%), 98.3% (97.5-98.8%), 95.8% (94.0-97.1%), and 99.7% (99.3-99.9%). Median (interquartile ranges) time to culture-positivity (and rifampicin and isoniazid DST) was 10 (9-13) days for conventional MODS and 8.5 (7-11) for MODS Kit (p<0.01). Direct rifampicin and isoniazid DST in MODS kit was almost universally concordant with conventional MODS (97.9% agreement, 665/679 evaluable samples) and reference indirect DST (97.9% agreement, 687/702 evaluable samples). CONCLUSIONS: MODS kit delivers performance indistinguishable from conventional MODS and offers a convenient, affordable alternative with enhanced safety from the sealing silicone lid. The availability in the marketplace of this platform, which conforms to European standards (CE-marked), readily repurposed for second-line DST in the near future, provides a fresh opportunity for improving equity of access to TB diagnosis and first and second-line DST in settings where the need is greatest

    Neural correlates of moral judgment in pedophilia

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    Pedophilia is a sexual preference that is often associated with child sex offending (CSO). Sexual urges towards prepubescent children and specifically acting upon those urges are universally regarded as immoral. However, up until now, it is completely unknown whether moral processing of sexual offenses is altered in pedophiles. A total of 31 pedophilic men and 19 healthy controls were assessed by using functional magnetic resonance imaging (fMRI) in combination with a moral judgment paradigm consisting of 36 scenarios describing different types of offenses. Scenarios depicting sexual offenses against children compared to those depicting adults were associated with higher pattern of activation in the left temporo-parietal-junction (TPJ) and left posterior insular cortex, the posterior cingulate gyrus as well as the precuneus in controls relative to pedophiles, and vice versa. Moreover, brain activation in these areas were positively associated with ratings of moral reprehensibility and negatively associated with decision durations, but only in controls. Brain activation, found in key areas related to the broad network of moral judgment, theory of mind and (socio-)moral disgust - point to different moral processing of sexual offenses in pedophilia in general. The lack of associations between brain activation and behavioral responses in pedophiles further suggest a biased response pattern or dissected implicit valuation processes

    Teor de óleo essencial de Ocimum selloi Benth. sob diferentes doses de compostos orgânicos.

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    Em espécies bioativas, a aplicação de compostos orgânicos tem sido relacionada à produção de metabólitos secundários. No presente estudo, avaliou-se o efeito de diferentes doses de compostos orgânicos no teor de óleo essencial de alfavaca anisada, fornecendo bases científicas para agricultura orgânica. Em Curitiba-PR, ano de 2008, num delineamento em blocos ao acaso, com três repetições, doses (0, 0,85, 1,7 e 3 t.ha-1) de compostos estabilizados (A, B, C e D), elaborados com diferentes materiais orgânicos, foram utilizadas no cultivo de alfavaca anisada. O espaçamento utilizado em cultivo protegido irrigado foi de 0,5m entre linhas por 1,0m entre plantas. Aos seis meses de cultivo, amostras compostas de folhas foram coletadas e submetidas ao processo de hidrodestilação, por meio do aparelho do tipo Clevenger, para quantificação do óleo essencial. Em solo com acúmulo de matéria orgânica as doses e compostos avaliados não influenciaram o teor de óleo essencial de Ocimum selloi Beth.Disponível também em: Cadernos de Agroecologia, V. 5, n.1, 2010

    Neural processing associated with cognitive empathy in pedophilia and child sexual offending

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    Behavioral studies found evidence for superior cognitive empathy (CE) in pedophilic men without a history of child sexual offending (P - CSO) compared to pedophilic men with a history of child sexual offending (P + CSO). Functional magnetic resonance imaging (fMRI) studies also point to differences between P - CSO and P + CSO. Neural processing associated with CE has not yet been investigated. Therefore, the present study aimed to explore the neural correlates of CE in subjects with pedophilia with (P + CSO) and without (P - CSO) child sexual offending. 15 P + CSO, 15 P - CSO and 24 teleiophilic male controls (TC) performed a CE task during fMRI. We observed reduced activation in the left precuneus (Pcu) and increased activation in the left anterior cingulate cortex (ACC) in P - CSO compared to P + CSO. P - CSO also showed stronger connectivity between these regions, which might reflect a top-down modulation of the Pcu by the ACC toward an increased self-focused emotional reaction in social situations. There was also evidence for increased right superior temporal gyrus activation in P - CSO that might constitute a potentially compensatory recruitment due to the dampened Pcu activation. These findings provide first evidence for altered neural processing of CE in P - CSO and underline the importance of addressing CE in pedophilia and CSO in order to uncover processes relevant to effective prevention of child sexual abuse

    New Dynamic Monte Carlo Renormalization Group Method

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    The dynamical critical exponent of the two-dimensional spin-flip Ising model is evaluated by a Monte Carlo renormalization group method involving a transformation in time. The results agree very well with a finite-size scaling analysis performed on the same data. The value of z=2.13±0.01z = 2.13 \pm 0.01 is obtained, which is consistent with most recent estimates

    Nicotine modulates the long-lasting storage of fear memory

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    Late post-training activation of the ventral tegmental area (VTA)–hippocampus dopaminergic loop controls the entry of information into long-term memory (LTM). Nicotinic acetylcholine receptors (nAChR) modulate VTA function, but their involvement in LTM storage is unknown. Using pharmacological and behavioral tools, we found that α7-nAChR-mediated cholinergic interactions between the pedunculopontine tegmental nucleus and the medial prefrontal cortex modulate the duration of fear-motivated memories, maybe by regulating the activation state of VTA–hippocampus dopamine connections.Fil: Lima, Ramón H.. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; ArgentinaFil: Radiske, Andressa. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; ArgentinaFil: Köhler, Cristiano A.. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; ArgentinaFil: González, María Carolina. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rossato, Janine Inez. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bevilaqua, Lia R.. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; ArgentinaFil: Medina, Jorge Horacio. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cammarota, Martin Pablo. Pontificia Universidade Catolica Do Rio Grande Do Sul; Brasil. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
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