17 research outputs found
Marine Biodiversity in the Caribbean: Regional Estimates and Distribution Patterns
This paper provides an analysis of the distribution patterns of marine biodiversity and summarizes the major activities of the Census of Marine Life program in the Caribbean region. The coastal Caribbean region is a large marine ecosystem (LME) characterized by coral reefs, mangroves, and seagrasses, but including other environments, such as sandy beaches and rocky shores. These tropical ecosystems incorporate a high diversity of associated flora and fauna, and the nations that border the Caribbean collectively encompass a major global marine biodiversity hot spot. We analyze the state of knowledge of marine biodiversity based on the geographic distribution of georeferenced species records and regional taxonomic lists. A total of 12,046 marine species are reported in this paper for the Caribbean region. These include representatives from 31 animal phyla, two plant phyla, one group of Chromista, and three groups of Protoctista. Sampling effort has been greatest in shallow, nearshore waters, where there is relatively good coverage of species records; offshore and deep environments have been less studied. Additionally, we found that the currently accepted classification of marine ecoregions of the Caribbean did not apply for the benthic distributions of five relatively well known taxonomic groups. Coastal species richness tends to concentrate along the Antillean arc (Cuba to the southernmost Antilles) and the northern coast of South America (Venezuela – Colombia), while no pattern can be observed in the deep sea with the available data. Several factors make it impossible to determine the extent to which these distribution patterns accurately reflect the true situation for marine biodiversity in general: (1) highly localized concentrations of collecting effort and a lack of collecting in many areas and ecosystems, (2) high variability among collecting methods, (3) limited taxonomic expertise for many groups, and (4) differing levels of activity in the study of different taxa
NEOTROPICAL XENARTHRANS: a data set of occurrence of xenarthran species in the Neotropics
Xenarthrans – anteaters, sloths, and armadillos – have essential functions for ecosystem maintenance, such as insect control and nutrient cycling, playing key roles as ecosystem engineers. Because of habitat loss and fragmentation, hunting pressure, and conflicts with 24 domestic dogs, these species have been threatened locally, regionally, or even across their full distribution ranges. The Neotropics harbor 21 species of armadillos, ten anteaters, and six sloths. Our dataset includes the families Chlamyphoridae (13), Dasypodidae (7), Myrmecophagidae (3), Bradypodidae (4), and Megalonychidae (2). We have no occurrence data on Dasypus pilosus (Dasypodidae). Regarding Cyclopedidae, until recently, only one species was recognized, but new genetic studies have revealed that the group is represented by seven species. In this data-paper, we compiled a total of 42,528 records of 31 species, represented by occurrence and quantitative data, totaling 24,847 unique georeferenced records. The geographic range is from the south of the USA, Mexico, and Caribbean countries at the northern portion of the Neotropics, to its austral distribution in Argentina, Paraguay, Chile, and Uruguay. Regarding anteaters, Myrmecophaga tridactyla has the most records (n=5,941), and Cyclopes sp. has the fewest (n=240). The armadillo species with the most data is Dasypus novemcinctus (n=11,588), and the least recorded for Calyptophractus retusus (n=33). With regards to sloth species, Bradypus variegatus has the most records (n=962), and Bradypus pygmaeus has the fewest (n=12). Our main objective with Neotropical Xenarthrans is to make occurrence and quantitative data available to facilitate more ecological research, particularly if we integrate the xenarthran data with other datasets of Neotropical Series which will become available very soon (i.e. Neotropical Carnivores, Neotropical Invasive Mammals, and Neotropical Hunters and Dogs). Therefore, studies on trophic cascades, hunting pressure, habitat loss, fragmentation effects, species invasion, and climate change effects will be possible with the Neotropical Xenarthrans dataset
Proyecto, investigación e innovación en urbanismo, arquitectura y diseño industrial
Actas de congresoLas VII Jornadas de Investigación “Encuentro y Reflexión” y I Jornadas de Investigación de becarios y doctorandos. Proyecto, investigación e innovación en Urbanismo, Arquitectura y Diseño Industrial se centraron en cuatro ejes: el proyecto; la dimensión tecnológica y la gestión; la dimensión social y cultural y la enseñanza en Arquitectura, Urbanismo y Diseño Industrial, sustentados en las líneas prioritarias de investigación definidas epistemológicamente en el Consejo Asesor de Ciencia y Tecnología de esta Universidad Nacional de Córdoba.
Con el objetivo de afianzar continuidad, formación y transferencia de métodos, metodología y recursos se incorporó becarios y doctorandos de los Institutos de investigación.
La Comisión Honoraria la integraron las tres Secretarias de Investigación de la Facultad, arquitectas Marta Polo, quien fundó y María del Carmen Franchello y Nora Gutiérrez Crespo quienes continuaron la tradición de la buena práctica del debate en la cotidianeidad de la propia Facultad.
Los textos que conforman las VII Jornadas son los avances y resultados de las investigaciones realizadas en el bienio 2016-2018.Fil: Novello, María Alejandra. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Repiso, Luciana. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Mir, Guillermo. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Brizuela, Natalia. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Herrera, Fernanda. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Períes, Lucas. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Romo, Claudia. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Gordillo, Natalia. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; ArgentinaFil: Andrade, Elena Beatriz. Universidad Nacional de Córdoba. Facultad de Arquitectura, Urbanismo y Diseño; Argentin
Chemoprophylactic activity of metformin during <i>E</i>. <i>granulosus</i> cyst development.
<p>(A) Box plot showing the comparative distribution of the weight (g) of cysts recovered from untreated (C) and Met-treated (Met, 50 mg/kg/d) mice. A significant cyst weight reduction (**<i>p</i> < 0.01) was achieved in treated animals. (B) Representative SEM (a, b, e, f) and TEM (c, d, g, h) images of hydatid cysts recovered from untreated control mice (a-d) compared with Met-treated mice (e-h). ll, laminated layer; mt, microtriches; dc, distal cytoplasm; gl, germinal layer; nu, nucleus; ly, lysosomes; gly, glycogen storage; a, autophagosomes; al, autophagolysosome; cc, calcareous corpuscles. Bars indicate: 50 μm in (a, e), 10 μm in (b, f) and 1 μm in (c, d, g, h). (C) Number of cysts obtained from untreated and Met-treated mice as indicated in (A).</p
Therapeutic efficacy study in <i>E</i>. <i>granulosus</i> infected mice.
<p>(A) Box plots showing the comparative distribution of the weight (g) of cysts recovered from untreated mice (C) and treated with albendazole (ABZ, 5 mg/kg/d), metformin (Met, 50 mg/kg/d) and the combination of both drugs (ABZ+Met) for 60 days. The weight of cysts was significantly decreased upon all treatments compared with the control (***<i>p</i> < 0.01), but the decrease was more prominent in the group receiving the combined treatment than in those with either drug alone (**<i>p</i> < 0.05); in turn, weight reduction was greater with Met than with ABZ (*<i>p</i> < 0.2). (B) Representative SEM (a, d, g, j) and TEM (b, c, e, f, h, i, k, l) images of hydatid cysts recovered from untreated mice (a, b, c) or treated with Met (d, e, f), ABZ (g, h, i) and ABZ+Met (j, k, l). ll, laminated layer; mt, microtriches; dc, distal cytoplasm; gl, germinal layer; nu, nucleus; ly, lysosomes (arrowheads); ve: vesicles (double-headed arrow); gly, glycogen storage; a, autophagosomes. Bars indicate: 20 μm in (a, d, g, j), 1 μm in (b, e, f, h, I, k, l), and 0.2 μm in (c). (C) Intracystic concentrations of Met from cysts recovered from Met- or ABZ+Met-treated mice in the experiment indicated in (A). (D) Number of cysts obtained from untreated and pharmacologically treated mice as indicated in (A). *Statistically significant difference (<i>p</i> < 0.05) in (C) and (D).</p
<i>In vitro</i> effect of metformin and its combination with low concentration of albendazole sulphoxide on viability of protoscoleces and metacestodes of <i>E</i>. <i>granulosus</i>.
<p>Viability of metacestodes (MTC) (A) and protoscoleces (PTS) (B) incubated for 7 and 27 days, respectively, with 1 and 5 mM of metformin alone (Met), 2.5 μM albendazole sulphoxide alone (ABZSO) and 1 and 5 mM Met plus 2.5 μM ABZSO in combination. Parasites incubated in culture medium containing DMSO served as controls. Data are the mean ± S.D. of three independent experiments. ***Statistically significant difference (<i>p</i> < 0.05) compared with control.</p
Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation
The effect of Lactobacillus casei and Bifidobacterium breve on antibiotic-associated diarrhea treatment: randomized double-blind clinical trial
Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation
Exposure to stress elicits excitoxicity and neuroinflammation in the brain, contributing to cell death and damage in stress-related neurological and neuropsychiatric diseases. The endocannabinoid system is present in stress-responsive neural circuits and has been proposed as an endogenous neuroprotective system activated in some neuropathological scenarios to restore homeostasis. To elucidate the possible regulatory role of cannabinoid receptor 1 (CB1) in stress-induced excitotoxicity and neuroinflammation, both genetic and pharmacological approaches were used alternatively: (1) wild-type (WT) and CB1 knockout mice (CB1-KO) were exposed to immobilization/acoustic stress (2 h/day for 4 days) and (2) to specifically activate CB1, the selective CB1 agonist Arachidonyl-2′-chloroethylamide (ACEA) (2.5 mg/kg) was intraperitoneally administered daily to some groups of animals. Stress exposure increased CB1 mRNA and protein expression in the prefrontal cortex of WT mice in a mechanism related to N-methyl--aspartate glutamate receptor activation. Daily ACEA pretreatment prevented stress-induced: (1) upregulation of CB1 mRNA and protein, (2) decrease in glutamate uptake and glutamate astroglial transporter excitatory amino acid transporter 2 expression, (3) increase in consecutive proinflammatory molecules, such as cytokines (tumor necrosis factor-α and MCP-1), nuclear factor kappa B, and enzymatic sources, such as inducible nitric oxide synthase (NOS-2) and cyclooxygenase-2 (COX-2), (4) increase in lipid peroxidation; although having no effect on plasma corticosterone. Interestingly, a possible related mechanism could be the positive ACEA modulation of the antiinflammatory pathway deoxyprostaglandin/peroxisome proliferator-activated receptor γ (15d-PGJ2/PPARγ). Conversely, KO animal experiments indicated that a lack of CB1 produces hypothalamic/pituitary/adrenal (HPA) axis dysregulation and exacerbates stress-induced excitotoxic/neuroinflammatory responses. These multifaceted neuroprotective effects suggest that CB1 activation could be a new therapeutic strategy against neurological/neuropsychiatric pathologies with HPA axis dysregulation and an excitotoxic/neuroinflammatory component in their pathophysiology
Volumen 18 Número 1
Revista seriada del Instituto Humboldt en asocio con el Invemar, el Instituto de Ciencias Naturales (ICN) y el Missouri Botanical Garden, como una estrategia para ampliar la base del conocimiento de uno de los países con mayor diversidad biológica del mundo.
Inicia como una publicación de listados de especies pero en 2005 amplía su espectro temático hacia la sistemática y la biogeografía. En 2010, a propósito del Año Internacional de la Biodiversidad y en pro del conocimiento, la conservación y el uso sostenible de la biodiversidad, se abre a un público más amplio, considerando trabajos inéditos de investigación sobre botánica, zoología, ecología, biología, limnología, pesquerías, conservación, manejo de recursos y uso de la biodiversidad, con buena aceptación por parte de la comunidad científica y académica. En 2013, en asocio con el SiB Colombia y con el apoyo de la GBIF, se institucionaliza la inclusión de Artículos de Datos (Data Papers) en Biota Colombiana