2,798 research outputs found

    Cloud Bursting and Cube Processing

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    Build and configure cloud bursting solution

    Cloud Cybersecurity, VMs and Containers

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    Establishing and monitoring cloud security within an OpenStack Clou

    Hawkins v. Town of Shaw: The Court as City Manager

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    For over one hundred years Congress and the federal courts have pursued the goal of racial equality in the United States. In areas such as voting rights, public accommodations, and housing, Congress and the courts have interacted closely, with broad judicial interpretations upholding major remedial legislation. Moreover, when confronted by official state sources of racial discrimination, courts have traditionally responded to the clear command of the equal protection clause of the fourteenth amendment without awaiting congressional action. Brown v. Board of Education stands as perhaps the best known instance in which a court has, on its own, ordered the elimination of disparate treatment based on race. Thus, when in Hawkins v. Town of Shaw, the United States Court of Appeals for the Fifth Circuit ordered a small Mississippi Delta town to end discrimination in the quantity and quality of municipal services it provided its black citizens, the court acted in keeping with this tradition

    The Internet: An Assessment of Student Perceptions

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    Analysis of Cloud Bursting on Openstack Infrastructure to AWS

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    Cloud computing is the development of distributed and parallel computing that seeks to provide a new model of business computing by automating services and efficiently storing proprietary data. Cloud bursting is one of the cloud computing techniques that adopts the hybrid cloud model which seeks to expand the resources of a private cloud through the integration with a public cloud infrastructure. In this paper, the viability of cloud bursting is experimented and an attempt to integrate AWS EC2 onto an Openstack cloud environment using the Openstack OMNI driver is conducted

    Blockchain Storage – Drive Configurations and Performance Analysis

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    This project will analyze the results of trials implementing various storage methods on Geth nodes to synchronize and maintain a full-archive state of the Ethereum blockchain. The purpose of these trials is to gain deeper insight to the process of lowering cost and increasing efficiency of blockchain storage using available technologies, analyzing results of various storage drives under similar conditions. It provides performance analysis and describes performance of each trial in relation to the others

    Spa47 is an oligomerization-activated type three secretion system (T3SS) ATPase from \u3cem\u3eShigella flexneri\u3c/em\u3e

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    Gram-negative pathogens often use conserved type three secretion systems (T3SS) for virulence. The Shigella type three secretion apparatus (T3SA) penetrates the host cell membrane and provides a unidirectional conduit for injection of effectors into host cells. The protein Spa47 localizes to the base of the apparatus and is speculated to be an ATPase that provides the energy for T3SA formation and secretion. Here, we developed an expression and purification protocol, producing active Spa47 and providing the first direct evidence that Spa47 is a bona fide ATPase. Additionally, size exclusion chromatography and analytical ultracentrifugation identified multiple oligomeric species of Spa47 with the largest greater than 8 fold more active for ATP hydrolysis than the monomer. An ATPase inactive Spa47 point mutant was then engineered by targeting a conserved Lysine within the predicted Walker A motif of Spa47. Interestingly, the mutant maintained a similar oligomerization pattern as active Spa47, but was unable to restore invasion phenotype when used to complement a spa47 null S. flexneri strain. Together, these results identify Spa47 as a Shigella T3SS ATPase and suggest that its activity is linked to oligomerization, perhaps as a regulatory mechanism as seen in some related pathogens. Additionally, Spa47 catalyzed ATP hydrolysis appears to be essential for host cell invasion, providing a strong platform for additional studies dissecting its role in virulence and providing an attractive target for anti-infective agents

    Balmer-dominated shocks in Tycho's SNR: omnipresence of CRs

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    We present wide-field, spatially and highly resolved spectroscopic observations of Balmer filaments in the northeastern rim of Tycho's supernova remnant in order to investigate the signal of cosmic-ray (CR) acceleration. The spectra of Balmer-dominated shocks (BDSs) have characteristic narrow (FWHM ∼\sim 10 kms−1^{-1}) and broad (FWHM ∼\sim 1000 kms−1^{-1}) Hα\alpha components. CRs affect the Hα\alpha-line parameters: heating the cold neutrals in the interstellar medium results in broadening of the narrow Hα\alpha-line width beyond 20 kms−1^{-1}, but also in reduction of the broad Hα\alpha-line width due to energy being removed from the protons in the post-shock region. For the first time we show that the width of the narrow Hα\alpha line, much larger than 20 kms−1^{-1}, is not a resolution or geometric effect nor a spurious result of a neglected intermediate (FWHM ∼\sim 100 kms−1^{-1}) component resulting from hydrogen atoms undergoing charge exchange with warm protons in the broad-neutral precursor. Moreover, we show that a narrow line width ≫\gg 20 kms−1^{-1} extends across the entire NE rim, implying CR acceleration is ubiquitous, and making it possible to relate its strength to locally varying shock conditions. Finally, we find several locations along the rim, where spectra are significantly better explained (based on Bayesian evidence) by inclusion of the intermediate component, with a width of 180 kms−1^{-1} on average.Comment: Proceeding for contributed talk at the IAU Symposium No. 331: "SN 1987A, 30 years later - Cosmic Rays and Nuclei from Supernovae and their Aftermaths", 2017, La Reunion Island; References correcte
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