791 research outputs found
Mapping the VCU Campus Food Environment
Preliminary research from a related VCU faculty team indicated that roughly ⅓ of all VCU students experience some level of food insecurity. Inventions to remedy this dire situation will require a more complete picture of the campus food environment. This project documented aspects of that environment. Our research team surveyed vending machines within Monroe Park buildings and facilities, along with nearby corner stores that were easily accessible to the university. Our team employed two instruments from the nationally recognized Nutritional Environment Measure Survey (NEMS), a toolkit created by Penn State University, to determine the nutritional quality of the campus food environment through direct observation. In addition to the NEMS data collection, our research team administered virtual student questionnaires to gauge general usage and attitudes towards food options on campus. VCU students were surveyed between Fall 2020 and Spring 2021 during the COVID-19 pandemic; and our data collection pivoted to incorporate the effects of the pandemic on campus. Findings are compiled in a geospatial map of the Monroe Park campus and surrounding areas. Within the interactive map, vending and corner store options were identified by the NEMS award systems along with their observation notes. Our findings concluded all snack and some beverage machines on campus received no NEMS award due to the lack of healthy options. Our hope in representing the data in a visually informed layout will incite action by the university administration to implement new opportunities to ensure a healthy and balanced food environment for the VCU community.https://scholarscompass.vcu.edu/gradposters/1135/thumbnail.jp
The Influence of Simulated Drowning Audits on Lifeguard Surveillance and Swimmer Risk-Taking at Public Swimming Pools
An alarming number of injuries and drowning events occur at lifeguarded swimming pools. One strategy used in the aquatics industry to improve swimming safety is simulated drowning lifeguard audits. During audits, supervisors arrive unannounced and ask on-duty lifeguard(s) to rescue a dummy. This study tested whether audits effectively improve lifeguard surveillance and reduce swimmer risk-taking behaviors. A pre-post design examined lifeguard surveillance and swimmer risk-taking prior to, 3 days after, and a month after conducting unannounced lifeguard audits at 14 public swimming pools. Lifeguard surveillance and swimmer risk-taking were assessed via behavioral observation. Following the audits, lifeguards were less distracted and swimmers took fewer risks. Simulated drowning lifeguard audits appear to offer a useful strategy to improve lifeguard surveillance and decrease swimmer risk-taking at public swimming pools
Unique transcriptomic landscapes identified in idiopathic spontaneous and infection related preterm births compared to normal term births.
Preterm birth (PTB) is leading contributor to infant death in the United States and globally, yet the underlying mechanistic causes are not well understood. Histopathological studies of preterm birth suggest advanced villous maturity may have a role in idiopathic spontaneous preterm birth (isPTB). To better understand pathological and molecular basis of isPTB, we compared placental villous transcriptomes from carefully phenotyped cohorts of PTB due to infection or isPTB between 28-36 weeks gestation and healthy term placentas. Transcriptomic analyses revealed a unique expression signature for isPTB distinct from the age-matched controls that were delivered prematurely due to infection. This signature included the upregulation of three IGF binding proteins (IGFBP1, IGFBP2, and IGFBP6), supporting a role for aberrant IGF signaling in isPTB. However, within the isPTB expression signature, we detected secondary signature of inflammatory markers including TNC, C3, CFH, and C1R, which have been associated with placental maturity. In contrast, the expression signature of the gestational age-matched infected samples included upregulation of proliferative genes along with cell cycling and mitosis pathways. Together, these data suggest an isPTB molecular signature of placental hypermaturity, likely contributing to the premature activation of inflammatory pathways associated with birth and providing a molecular basis for idiopathic spontaneous birth
A revised edition of the readiness to change questionnaire (treatment version)
The UK Alcohol Treatment Trial provided an opportunity to examine the factor structure of the Readiness to Change Questionnaire-Treatment Version (RCQ[TV]) in a large sample (N = 742) of individuals in treatment for alcohol problems who were given the RCQ[TV] at baseline, 3-months and 12-months follow-up. Confirmatory factor analysis of the previously reported factor structure (5 items for each of Precontemplation, Contemplation and Action scales) resulted in a relatively poor fit to the data. Removal of one item from each of the scales resulted in a 12-item instrument for which goodness-of-fit indices were improved, without loss of internal consistency of the three scales, on all three measurement occasions. Inspection of relationships between stage allocation by the new instrument and negative alcohol outcome expectancies provided evidence of improved construct validity for the revised edition of the RCQ[TV]. There was also a strong relationship between stage allocation at 3-months follow-up and outcome of treatment at 12 months. The revised edition of the RCQ[TV] offers researchers and clinicians a shorter and improved measurement of stage of change in the alcohol treatment population
A Novel, Contactless, Portable “Spot-Check” Device Accurately Measures Respiratory Rate
Respiratory rate (RR) is an important vital sign used in the assessment of acutely ill patients. It is also used as to predict serious deterioration in a patient's clinical condition. Convenient electronic devices exist for measurement of pulse, blood pressure, oxygen saturation and temperature. Although devices which measure RR exist, none has entered everyday clinical practice.
We developed a contactless portable respiratory rate monitor (CPRM) and evaluated the agreement in respiratory rate measurements between existing methods and our new device. The CPRM uses thermal anemometry to measure breath signals during inspiration and expiration.
RR data were collected from 52 healthy adult volunteers using respiratory inductance plethysmography (RIP) bands (established contact method), visual counting of chest movements (established non-contact method) and the CPRM (new method), simultaneously. Two differently shaped funnel attachments were evaluated for each volunteer.
Data showed good agreement between measurements from the CPRM and the gold standard RIP, with intra-class correlation coefficient (ICC): 0.836, mean difference 0.46 and 95% limits of agreement of -5.90 to 6.83. When separate air inlet funnels of the CPRM were analysed, stronger agreement was seen with an elliptical air inlet; ICC 0.908, mean difference 0.37 with 95% limits of agreement -4.35 to 5.08.
A contactless device for accurately and quickly measuring respiratory rate will be an important triage tool in the clinical assessment of patients. More testing is needed to explore the reasons for outlying measurements and to evaluate in the clinical setting
Can consumers learn to ask three questions to improve shared decision making? A feasibility study of the ASK (AskShareKnow) Patient–Clinician Communication Model® intervention in a primary health-care setting
Funded by Informed Medical Decisions Foundation. Grant Number: #0175-1 National Health and Medical Research Council Public Health Training Fellowship. Grant Number: 568962Peer reviewedPublisher PD
Genetic testing and gene therapy in retinal diseases:Knowledge and perceptions of optometrists in Australia and New Zealand
Ethnicity as a Moderator of Treatment Effects on Parent-Child Interaction for Children With ADHD
Objective:
To examine ethnic differences in observed parenting and child behavior and the moderating effects
of ethnicity on the relationship between treatment and parent and child behavior.
Method:
Observations of 508 children with ADHD (ages 7–9) and their caregivers, collected during the
Multimodal Treatment Study of ADHD, were analyzed using univariate and mixed-model ANOVAs.
Results:
Although baseline parenting practices differed by ethnic group, ethnicity did not moderate the
relationship between treatment and either parenting or child behavior.
Conclusion:
Consistent with data from normative samples, parents of children with ADHD differed by ethnicity
in their utilization of certain parenting strategies. However, different ethnic groups did not differ on benefit
received from treatments for ADHD, measured by parent and child behavior. Although ethnicity did not
emerge as a moderator, ethnic minority family engagement in treatment may be increased by recognizing
different parenting strategies and modifying interventions accordingly. (J. of Att. Dis. 2010; 13(6) 592-600
Electrophilic PPARγ Ligands Attenuate IL-1β and Silica-Induced Inflammatory Mediator Production in Human Lung Fibroblasts via a PPARγ-Independent Mechanism
Acute and chronic lung inflammation is associated with numerous important disease pathologies including asthma, chronic obstructive pulmonary disease and silicosis. Lung fibroblasts are a novel and important target of anti-inflammatory therapy, as they orchestrate, respond to, and amplify inflammatory cascades and are the key cell in the pathogenesis of lung fibrosis. Peroxisome proliferator-activated receptor gamma (PPARγ) ligands are small molecules that induce anti-inflammatory responses in a variety of tissues. Here, we report for the first time that PPARγ ligands have potent anti-inflammatory effects on human lung fibroblasts. 2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid (CDDO) and 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) inhibit production of the inflammatory mediators interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), COX-2, and prostaglandin (PG)E2 in primary human lung fibroblasts stimulated with either IL-1β or silica. The anti-inflammatory properties of these molecules are not blocked by the PPARγ antagonist GW9662 and thus are largely PPARγ independent. However, they are dependent on the presence of an electrophilic carbon. CDDO and 15d-PGJ2, but not rosiglitazone, inhibited NF-κB activity. These results demonstrate that CDDO and 15d-PGJ2 are potent attenuators of proinflammatory responses in lung fibroblasts and suggest that these molecules should be explored as the basis for novel, targeted anti-inflammatory therapies in the lung and other organs
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