92 research outputs found
Enterprise Contextual Notifier, Contextual Tag Clouds towards more Relevant Awareness
International audienceOn the so-called Web 2.0, numerous Social Networking Sites (SNS) have known a tremendous success as they brought new ways to communicate, interact, learn about people, and share content with them. Besides improving informal social ties, transposing Awareness to the enterprise is very promising for promoting collaboration. However, it can easily lead to information overload, which means productivity loss. With our prototype, we propose a way to stimulate enterprise internal communication while improving the relevance of these interactions with the current working context of their users. This prototype is an efficient tool for cooperation and for discovering relevant people and knowledge
Rheological properties and structure of a semi-solid tin-lead alloy.
Massachusetts Institute of Technology. Dept. of Metallurgy and Materials Science. Thesis. 1974. Ph.D.MICROFICHE COPY ALSO AVAILABLE IN SCIENCE LIBRARY.Leaf number 102 omitted in paging. Vita.Includes bibliographical references.Ph.D
A User Profile Ontology For Situation-Aware Social Networking
International audienceToday, more and more people possess mobile devices. This enables them to have access to a wide range of services, but also to be contacted anytime, anywhere, which can cause discom- fort. Users should have full control on who can reach them and how, depending on their current situation: when at work, we wish a friend didn't interrupted us, but when having a family dinner, we wish a call related to work didn't occur. Even more, situation changes need to be detected in real-time, since preferences change a lot. We present in this paper an ontology-based user profile model, that allows users to have a situation-aware social network, by controlling how reachable they are for specific categories of people in a given situation
Propagation of an acoustic wave in a junction of two thin slots
In this research report, we analyze via the theory of matched asymptotics the propagation of a time harmonic acoustic wave in a junction of two thin slots. This allows us to propose improved Kirchoff conditions for the 1D limit model. These conditions are analyzed and validated numerically
Study of propagation of acoustic waves in junction of thin slots
In this document, we analyze via the theory of matched asymptotics the propagation of a time domain acoustic wave in a junction of thin slots. This allows us to propose Improved Kirchhoff conditions for the 1D limit problem. These conditions are analyzed and validated numerically
Kiri Karl Morgensternile, Paris
http://tartu.ester.ee/record=b1826079~S1*es
Identification and functional characterization of the pheromone biosynthesis activating neuropeptide receptor isoforms from Mamestra brassicae
Communication : 28th Conference of European Comparative Endocrinologists ; Organisme : European Society for Comparative Endocrinology (ESCE), Louvain, Belgique ; date de début de l'événement : 2016-08-21, date de fin de l'évenement : 2016-08-25International audienceIn most moth species, including Mamestra brassicae, pheromone biosynthesis activating neuropeptide (PBAN) regulates pheromone production. Generally, PBAN acts directly on the pheromone gland (PG) cells via its specific G protein-coupled receptor (i.e. PBANR) with Ca2+ as a second messenger. In this study, we identified cDNAs encoding three variants (A, B and C) of the M. brassicae PBANR (Mambr-PBANR). The full-length coding sequences were transiently expressed in cultured Trichoplusia ni cells and Sf9 cells for functional characterization. All three isoforms dose-dependently mobilized extracellular Ca2+ in response to PBAN analogs with Mambr-PBANR-C exhibiting the greatest sensitivity. Fluorescent confocal microscopy imaging studies demonstrated binding of a rhodamine red-labeled ligand (RR10CPBAN) to all three Mambr-PBANR isoforms. RR10CPBAN binding did not trigger ligand-induced internalization in cells expressing PBANR-A, but did in cells expressing the PBANR-B and-C isoforms. Furthermore, activation of the PBANR-B and-C isoforms with the 18 amino acid Mambr-pheromonotropin resulted in co-localization with a Drosophila melanogaster arrestin homolog (Kurtz), whereas stimulation with an unrelated peptide had no effect. PCR-based profiling of the three transcripts revealed a basal level of expression throughout development with a dramatic increase in PG transcripts from the day of adult emergence with PBANR-C being the most abundant
Molecular Characterization of MbraOR16, a Candidate Sex Pheromone Receptor in Mamestra brassicae (Lepidoptera: Noctuidae)
Sex pheromone communication in Lepidoptera has long been a valuable model system for studying fundamental aspects of olfaction and its study has led to the establishment of environmental-friendly pest control strategies. The cabbage moth, Mamestra brassicae (Linnaeus) (Lepidoptera: Noctuidae), is a major pest of Cruciferous vegetables in Europe and Asia. Its sex pheromone has been characterized and is currently used as a lure to trap males; however, nothing is known about the molecular mechanisms of sex pheromone reception in male antennae. Using homology cloning and rapid amplification of cDNA ends-PCR strategies, we identified the first candidate pheromone receptor in this species. The transcript was specifically expressed in the antennae with a strong male bias. In situ hybridization experiments within the antennae revealed that the receptor-expressing cells were closely associated with the olfactory structures, especially the long trichoid sensilla known to be pheromone-sensitive. The deduced protein is predicted to adopt a seven-transmembrane structure, a hallmark of insect odorant receptors, and phylogenetically clustered in a clade that grouped a majority of the Lepidoptera pheromone receptors characterized to date. Taken together, our data support identification of a candidate pheromone receptor and provides a basis for better understanding how this species detects a signal critical for reproduction
Combined coagulation and inflammation markers as predictors of venous thrombo-embolism and death in COVID-19
BackgroundThe COVID-19 pandemic related to SARS-CoV-2 virus was responsible for global pandemic. The severe form of the disease was linked to excessive activation of immune pathways together with a systemic cytokine storm response and thrombotic venous or arterial complications. Factors predicting severe outcomes including venous and/or pulmonary thrombosis (VT) and death were identified, but the prognostic role of their combination was not addressed extensively.ObjectivesWe investigated the role of prognostic factors from the coagulation or inflammatory pathways to better understand the outcome of the disease.MethodsFor this, we prospectively studied 167 SARS-CoV-2-positive patients from admission in intensive care units (ICU) or emergency departments from four academic hospitals over a 14-month period. Besides standard biology, we assessed serum concentrations of inflammatory markers, coagulation factors and peripheral blood cells immunophenotyping.ResultsThirty-nine patients (23.3%) developed VT and 30 patients (18%) died. By univariate analysis, C-reactive protein (CRP) level > 150 mg/L, interleukin-6 (IL-6) ≥ 20 pg/mL, D-dimers > 1,500 μg/L, ADAMTS13 activity ≤ 50%, VonConclusionA combination of coagulation and inflammatory markers can refine the prognostication of severe outcome in COVID-19, and could be useful for the initial evaluation of other types of viral infection
An Adaptive and Extensible Web-based Interface System for Interactive Video Contents Browsing
With the growing popularity of mobile devices (including phones and portable media players) and coverage of Internet access, we tend to develop the need of consuming video content on the move. Some technologies already allow end-users to watch TV and listen to news podcasts or download music videos on their devices. However, such services are restricted to a provider's selection of preformatted and linear content streams. Hence, we propose a web-based interface system that supports interactive contents navigation, making it possible for end-users to "surf" on video content like they are used to on the Web. This system is extensible to any specific domain of video contents, any webenabled platform, and to any browsing scheme. In this paper, we will explain the architecture and design of this system, propose an application for soccer videos and present the results of its user evaluation
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