Visión de la OCDE del rol que desempeña la educación superior para el desarrollo humano y social

En los últimos veinte años, el desarrollo de políticas en el ámbito local, nacional e internacional ha evidenciado que el desarrollo sostenible es el único marco estratégico que facilita un enfoque coordinado de problemas como la pobreza, la violación de los derechos humanos, la corrupción, la enfermedad física o mental, la pérdida de biodiversidad y el cambio climático. Las instituciones de educación superior (IES) de todo el mundo reconocen cada vez más su papel protagonista en los esfuerzos nacionales por desarrollar la sostenibilidad. Algunas de ellas aprovechan la oportunidad para hacer su contribución. Sin embargo, ni un solo país ha adoptado una orientación sistemática y estratégica a escala nacional al respecto.Peer Reviewe

Group V: Color Mixer

This project was an exercise in product design, modeling, and prototyping. The result of this process was a partially functional prototype which successfully met two of the three design goals

Fitting orbits to tidal streams with proper motions

The Galaxy's stellar halo seems to be a tangle of disrupted systems that have been tidally stretched out into streams. Each stream approximately delineates an orbit in the Galactic force-field. In the first paper in this series we showed that all six phase-space coordinates of each point on an orbit can be reconstructed from the orbit's path across the sky and measurements of the line-of-sight velocity along the orbit. In this paper we complement this finding by showing that the orbit can also be reconstructed if we know proper motions along the orbit rather than the radial velocities. We also show that accurate proper motions of stream stars would enable distances to be determined to points on the stream that are independent of any assumption about the Galaxy's gravitational potential. Such "Galactic parallaxes" would be as fundamental as conventional trigonometric parallaxes, but measureable to distances ~70 times further.Comment: 5 pages, 2 figures, submitted to MNRAS Letter

A comparative study of the superconductivity in the Holstein and optical Su-Schrieffer-Heeger models

Theoretical studies suggest that Su-Schrieffer-Heeger-like electron-phonon ($e$-ph) interactions can mediate high-temperature bipolaronic superconductivity that is robust against repulsive electron-electron interactions. Here we present a comparative analysis of the pairing and competing charge/bond correlations in the two-dimensional Holstein and optical Su-Schrieffer-Heeger (SSH) models using numerically exact determinant quantum Monte Carlo. We find that the SSH interactions support light bipolarons and strong superconducting correlations out to relatively large values of the $e$-ph coupling $\lambda$ and densities near half-filling, while the Holstein interaction does not due to the formation of heavy bipolarons and competing charge-density-wave order. We further find that the Holstein and SSH models have comparable pairing correlations in the weak coupling limit for carrier concentrations $\langle n \rangle \ll 1$, where competing orders and polaronic effects are absent. These results support the proposal that SSH (bi)polarons can support superconductivity to larger values of $\lambda$ in comparison to the Holstein polaron, but that the resulting $T_\mathrm{c}$ gains are small in the weak coupling limit. We also find that the SSH model's pairing correlations are suppressed after including a weak on-site Hubbard repulsion. These results have important implications for identifying and engineering bipolaronic superconductivity.Comment: 10 pages including appendice

Oxygen targeting in preterm infants using the Masimo SET Radical pulse oximeter

Background A pretrial clinical improvement project for the BOOST-II UK trial of oxygen saturation targeting revealed an artefact affecting saturation profiles obtained from the Masimo Set Radical pulse oximeter.Methods Saturation was recorded every 10 s for up to 2 weeks in 176 oxygen dependent preterm infants in 35 UK and Irish neonatal units between August 2006 and April 2009 using Masimo SET Radical pulse oximeters. Frequency distributions of % time at each saturation were plotted. An artefact affecting the saturation distribution was found to be attributable to the oximeter's internal calibration algorithm. Revised software was installed and saturation distributions obtained were compared with four other current oximeters in paired studies.Results There was a reduction in saturation values of 87-90%. Values above 87% were elevated by up to 2%, giving a relative excess of higher values. The software revision eliminated this, improving the distribution of saturation values. In paired comparisons with four current commercially available oximeters, Masimo oximeters with the revised software returned similar saturation distributions.Conclusions A characteristic of the software algorithm reduces the frequency of saturations of 87-90% and increases the frequency of higher values returned by the Masimo SET Radical pulse oximeter. This effect, which remains within the recommended standards for accuracy, is removed by installing revised software (board firmware V4.8 or higher). Because this observation is likely to influence oxygen targeting, it should be considered in the analysis of the oxygen trial results to maximise their generalisability

The mechanics of tidal streams

We present an analysis of the mechanics of thin streams, which are formed following the tidal disruption of cold, low-mass clusters in the potential of a massive host galaxy. The analysis makes extensive use of action-angle variables, in which the physics of stream formation and evolution is expressed in a particularly simple form. We demonstrate the formation of streams by considering examples in both spherical and flattened potentials, and we find that the action-space structures formed in each take on a consistent and characteristic shape. We demonstrate that tidal streams formed in realistic galaxy potentials are poorly represented by single orbits, contrary to what is often assumed. We further demonstrate that attempting to constrain the parameters of the Galactic potential by fitting orbits to such streams can lead to significant systematic error. However, we show that it is possible to predict accurately the track of streams from simple models of the action-space distribution of the disrupted cluster.Comment: 23 pages, 20 figures, to appear in MNRAS. Minor revisions in response to a referee; missing factor 2 added to eq (33) and following equations resulting in minor changes in result

Parasitic nematodes simultaneously suppress and benefit from coccidian coinfection in their natural mouse host

Within-host interactions among coinfecting parasites are common and have important consequences for host health and disease dynamics. However, these within-host interactions have traditionally been studied in laboratory mouse models, which often exclude important variation and use unnatural host–parasite combinations. Conversely, the few wild studies of within-host interactions often lack knowledge of parasite exposure and infection history. Here we exposed laboratory-reared wood mice (Apodemus sylvaticus) that were derived from wild-caught animals to two naturally-occurring parasites (nematode: Heligmosomoides polygyrus, coccidia: Eimeria hungaryensis) to investigate the impact of coinfection on parasite infection dynamics, and to determine if the host immune response mediates this interaction. Coinfection led to delayed worm expulsion and prolonged egg shedding in H. polygyrus infections and lower peak E. hungaryensis oocyst burdens. By comparing antibody levels between wild and colony-housed mice, we also found that wild mice had elevated H. polygyrus-IgG1 titres even if currently uninfected with H. polygyrus. Using this unique wild-laboratory system, we demonstrate, for the first time, clear evidence for a reciprocal interaction between these intestinal parasites, and that there is a great discrepancy between antibody levels measured in the wild vs those measured under controlled laboratory conditions in relation to parasite infection and coinfection

LMDA Canada: Canadian Caucus Newsletter, November 1999

Contents include: LMDA Canadian Caucus Membership, Letter from the Editor, Survey Results, Canadian Dramaturtle Goes to Oz, Translation on the St. Lawrence, Experimenting with the Audience, Feeding My Habit or Why I Stopped Being a Dramaturg and Went Back to School, Mini-Conference on Dramaturgy 1999, Canadians in Chicago, War of the Worlds, Dramaturging Dr. Faustus, Inside the Process: A New Angle on the Spring Festival of New Plays, ScriptLab: Millennium Approacheshttps://soundideas.pugetsound.edu/lmdanewsletter/1029/thumbnail.jp

Diagnosis of non-effusive feline infectious peritonitis by reverse transcriptase quantitative PCR from mesenteric lymph node fine-needle aspirates

The aim of this study was to evaluate a feline coronavirus (FCoV) reverse transcriptase quantitative PCR (RT-qPCR) on fine-needle aspirates (FNAs) from mesenteric lymph nodes (MLNs) collected in sterile saline for the purpose of diagnosing non-effusive feline infectious peritonitis (FIP) in cats. First, the ability of the assay to detect viral RNA in MLN FNA preparations compared with MLN biopsy preparations was assessed in matched samples from eight cats. Second, a panel of MLN FNA samples was collected from a series of cats representing non-effusive FIP cases (n = 20), FCoV-seropositive individuals (n = 8) and FCoV seronegative individuals (n = 18). Disease status of the animals was determined using a combination of gross pathology, histopathology and/or 'FIP profile', consisting of serology, clinical pathology and clinical signs. Viral RNA was detected in 18/20 non-effusive FIP cases; it was not detected in two cases that presented with neurological FIP. Samples from 18 seronegative non-FIP control cats and 7/8 samples from seropositive non-FIP control cats contained no detectable viral RNA. Thus, as a method for diagnosing non-effusive FIP, MLN FNA RT-qPCR had an overall sensitivity of 90.0% and specificity of 96.1%. In cases with a high index of suspicion of disease, RT-qPCR targeting FCoV in MLN FNA can provide important information to support the ante-mortem diagnosis of non-effusive FIP. Importantly, viral RNA can be reliably detected in MLN FNA samples in saline submitted via the national mail service. When applied in combination with biochemistry, haematology and serological tests in cases with a high index of suspicion of disease the results of this assay may be used to support a diagnosis of non-effusive FIP