Pressure distribution for the wing of the YAV-8B airplane; with and without pylons

Pressure distribution data have been obtained in flight at four span stations on the wing panel of the YAV-8B airplane. Data obtained for the supercritical profiled wing, with and without pylons installed, ranged from Mach 0.46 to 0.88. The altitude ranged from approximately 20,000 to 40,000 ft and the resultant Reynolds numbers varied from approximately 7.2 million to 28.7 million based on the mean aerodynamic chord. Pressure distribution data and flow visualization results show that the full-scale flight wing performance is compromised because the lower surface cusp region experiences flow separation for some important transonic flight conditions. This condition is aggravated when local shocks occur on the lower surface of the wing (mostly between 20 and 35 percent chord) when the pylons are installed for Mach 0.8 and above. There is evidence that convex fairings, which cover the pylon attachment flanges, cause these local shocks. Pressure coefficients significantly more negative than those for sonic flow also occur farther aft on the lower surface (near 60 percent chord) whether or not the pylons are installed for Mach numbers greater than or equal to 0.8. These negative pressure coefficient peaks and associated local shocks would be expected to cause increasing wave and separation drag at transonic Mach number increases

The Putative bZIP Transcripton Factor BzpN Slows Proliferation and Functions in the Regulation of Cell Density by Autocrine Signals in Dictyostelium

The secreted proteins AprA and CfaD function as autocrine signals that inhibit cell proliferation in Dictyostelium discoideum, thereby regulating cell numbers by a negative feedback mechanism. We report here that the putative basic leucine zipper transcription factor BzpN plays a role in the inhibition of proliferation by AprA and CfaD. Cells lacking BzpN proliferate more rapidly than wild-type cells but do not reach a higher stationary density. Recombinant AprA inhibits wild-type cell proliferation but does not inhibit the proliferation of cells lacking BzpN. Recombinant CfaD also inhibits wild-type cell proliferation, but promotes the proliferation of cells lacking BzpN. Overexpression of BzpN results in a reduced cell density at stationary phase, and this phenotype requires AprA, CfaD, and the kinase QkgA. Conditioned media from high-density cells stops the proliferation of wild-type but not bzpN− cells and induces a nuclear localization of a BzpN-GFP fusion protein, though this localization does not require AprA or CfaD. Together, the data suggest that BzpN is necessary for some but not all of the effects of AprA and CfaD, and that BzpN may function downstream of AprA and CfaD in a signal transduction pathway that inhibits proliferation

Functional analysis of the sporulation-specific SPR6 gene of Saccharomyces cerevisiae

The SPR6 gene of Saccharomyces cerevisiae encodes a moderately abundant RNA that is present at high levels only during sporulation. The gene contains a long open reading frame that could encode a hydrophilic protein approximately 21 kDa in size. This protein is probably produced by the yeast, because the lacZ gene of Escherichia coli is expressed during sporulation when fused to SPR6 in the expected reading frame. SPR6 is inessential for sporulation; mutants that lack SPR6 activity sporulate normally and produce viable ascospores. Nonetheless, the SPR6 gene encodes a function that is relevant to sporulating cells; the wild-type allele can enhance sporulation in strains that are defective for several SPR functions. SPR6 is located on chromosome V, 14.4 centimorgans centromere-distal to MET6 .Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46973/1/294_2004_Article_BF00318210.pd

SAAM: An Integrated Network Architecture for Integrated Services

The current network architecture is based predominantly on stand-alone routers. It is becoming overtaxed with the introduction of integrated services. In this paper, we propose a Server and Agent based Active network Management (SAAM) architecture that scales well with integrated services. SAAM relieves individual routers from most routing and network management tasks. Instead, it employs a small number of dedicated servers to perform these tasks on behalf of the routers. In particular, these servers maintain a path information base (PIB), with which network functions, such as QoS routing and re-routing of real-time flows, can be efficiently implemented. We describe a scaleable architecture for organizing the servers as well as a concrete design of the PIB. SAAM has the potential of offering a common platform where multiple network functions --- such as routing, resource reservation, network management, accounting and security --- can be integrated

The SAAM architecture : enabling integrated services

Computer networks of today are based predominantly on the TCP/IP protocol suite that provides best effort service. The current IP protocol excels in its simplicity and network fault tolerance. The way it implements this simplicity and fault tolerance, however, limits the protocol's ability to provide a guaranteed Quality of Service (QoS). A first Step in providing this QoS is to incorporate the concept of flow based routing. This thesis describes an implementation of the Server and Agent based Active network Management (SAAM) system architecture that incorporates flow based routing. The architecture contains servers that maintain a database that is used for assigning each flow to a path that will provide the needed QoS.http://archive.org/details/thesaamrchitectu1094539420U.S. Marine Corps (U.S.M.C.) authorsApproved for public release; distribution is unlimited