Winter ozone formation and VOC incremental reactivities in the Upper Green River Basin of Wyoming

The Upper Green River Basin (UGRB) in Wyoming experiences ozone episodes in the winter when the air is relatively stagnant and the ground is covered by snow. A modeling study was carried out to assess relative contributions of oxides of nitrogen (NO_x) and individual volatile organic compounds (VOCs), and nitrous acid (HONO) in winter ozone formation episodes in this region. The conditions of two ozone episodes, one in February 2008 and one in March 2011, were represented using a simplified box model with all pollutants present initially, but with the detailed SAPRC-07 chemical mechanism adapted for the temperature and radiation conditions arising from the high surface albedo of the snow that was present. Sensitivity calculations were conducted to assess effects of varying HONO inputs, ambient VOC speciation, and changing treatments of temperature and lighting conditions. The locations modeled were found to be quite different in VOC speciation and sensitivities to VOC and NO_x emissions, with one site modeled for the 2008 episode being highly NO_x-sensitive and insensitive to VOCs and HONO, and the other 2008 site and both 2011 sites being very sensitive to changes in VOC and HONO inputs. Incremental reactivity scales calculated for VOC-sensitive conditions in the UGRB predict far lower relative contributions of alkanes to ozone formation than in the traditional urban-based MIR scale and that the major contributors to ozone formation were the alkenes and the aromatics, despite their relatively small mass contributions. The reactivity scales are affected by the variable ambient VOC speciation and uncertainties in ambient HONO levels. These box model calculations are useful for indicating general sensitivities and reactivity characteristics of these winter UGRB episodes, but fully three-dimensional models will be required to assess ozone abatement strategies in the UGRB

Real-Time Planning with Multi-Fidelity Models for Agile Flights in Unknown Environments

Autonomous navigation through unknown environments is a challenging task that entails real-time localization, perception, planning, and control. UAVs with this capability have begun to emerge in the literature with advances in lightweight sensing and computing. Although the planning methodologies vary from platform to platform, many algorithms adopt a hierarchical planning architecture where a slow, low-fidelity global planner guides a fast, high-fidelity local planner. However, in unknown environments, this approach can lead to erratic or unstable behavior due to the interaction between the global planner, whose solution is changing constantly, and the local planner; a consequence of not capturing higher-order dynamics in the global plan. This work proposes a planning framework in which multi-fidelity models are used to reduce the discrepancy between the local and global planner. Our approach uses high-, medium-, and low-fidelity models to compose a path that captures higher-order dynamics while remaining computationally tractable. In addition, we address the interaction between a fast planner and a slower mapper by considering the sensor data not yet fused into the map during the collision check. This novel mapping and planning framework for agile flights is validated in simulation and hardware experiments, showing replanning times of 5-40 ms in cluttered environments.Comment: ICRA 201

Accurate object reconstruction by statistical moments

Statistical moments can offer a powerful means for object description in object sequences. Moments used in this way provide a description of the changing shape of the object with time. Using these descriptions to predict temporal views of the object requires efficient and accurate reconstruction of the object from a limited set of moments, but accurate reconstruction from moments has as yet received only limited attention. We show how we can improve accuracy not only by consideration of formulation, but also by a new adaptive thresholding technique that removes one parameter needed in reconstruction. Both approaches are equally applicable for Legendre and other orthogonal moments to improve accuracy in reconstruction

Network-based stratification of tumor mutations.

Many forms of cancer have multiple subtypes with different causes and clinical outcomes. Somatic tumor genome sequences provide a rich new source of data for uncovering these subtypes but have proven difficult to compare, as two tumors rarely share the same mutations. Here we introduce network-based stratification (NBS), a method to integrate somatic tumor genomes with gene networks. This approach allows for stratification of cancer into informative subtypes by clustering together patients with mutations in similar network regions. We demonstrate NBS in ovarian, uterine and lung cancer cohorts from The Cancer Genome Atlas. For each tissue, NBS identifies subtypes that are predictive of clinical outcomes such as patient survival, response to therapy or tumor histology. We identify network regions characteristic of each subtype and show how mutation-derived subtypes can be used to train an mRNA expression signature, which provides similar information in the absence of DNA sequence

Earth Flows Along Henry Creek, Northern Alaska

Many earth flows occurred during the summer of 1979 in the hilly terrain near Umiat, Alaska, particularly along Henry Creek. Most were shallow, involving only the tundra mat and no more than 1.5 m of the underlying mud. The summer of 1979 was the warmest and wettest for the period of record at Umiat, and precipitation was characterized by brief but intense localized rainstorms. Failure probably was triggered by the heavy rains and facilitated by an absorbent tundra mat over a clayey substrate, and perhaps in some cases by a thicker than normal active layer. Flows of this kind have occurred repeatedly in the Uniat area, most likely during summers in which climatic conditions were similar to those of 1979.Key words: earth flows, rainfall, temperature, active layer, bentonitic materials, Alask

Simple Calculations to Reduce Litigation Costs in Personal Injury Cases: Additional Empirical Support for the Offset Rule

This article demonstrates that if the nominal rate of interest equals the growth rate of nominal earnings, then a strong case can be made for calculating lump-sum damage awards by using the offset rule, i.e., by simply multiplying the annual loss by the number of years the loss is expected to continue. An examination of the Canadian data not only supports the offset rule, but also suggests that plaintiffs are being systematically undercompensated by rules currently in use

How to think about health promotion ethics

Health promotion ethics is moral deliberation about health promotion and its practice. Although academics and practitioners have been writing about ethics, and especially values, in health promotion for decades, health promotion ethics is now regaining attention within the broader literature on public health ethics. Health promotion is difficult to define, and this has implications for health promotion ethics. Health promotion can be approached in two complementary ways: as a normative ideal, and as a practice. We consider the normative ideal of health promotion to be that aspect of public health practice that is particularly concerned with the equity of social arrangements: it imagines that social arrangements can be altered to make things better for everyone, whatever their health risks, and seeks to achieve this in collaboration with citizens. This raises two main ethical questions. First: what is a good society? And then: what should health promotion contribute to a good society? The practice of health promotion varies widely. Discussion of its ethical implications has addressed four main issues: the potential for health promotion to limit or increase the freedom of individuals; health promotion as a source of collective benefit; the possibility that health promotion strategies might blame the victim or stigmatise those who are disabled, sick or at higher risk of disease; and the importance of distributing the benefits of health promotion fairly. Different people will make different moral evaluations on each of these issues in a way that is informed by, and informs, their vision of a good society and their understanding of the ends of health promotion. We conclude that future work in health promotion ethics will require thoughtfully connecting social and political philosophy with an applied, empirically informed ethics of practice